Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis
Glycolytic flux in Saccharomyces cerevisiae is dependent on RNA polymerase III and its negative regulator Maf1
Molecular dynamics of C99-bound γ-secretase reveal two binding modes with distinct compactness, stability, and active-site retention: implications for Aβ production
Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization
The cover image shows immunofluorescent labelling of Cx43-M257 (top) and WT Cx43 (bottom) gap junctions. Wei and colleagues (1137–1148) conclude that the calcium/calmodulin-dependent chemical gating mechanism of Cx43 gap junctions does not require the distal CT domain of Cx43. Image courtesy of Richard D. Veenstra.