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Volume 477, Issue 19

October 2020

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Cover Image

Cover Image

The cover image showing the crystal structure of human hemoglobin (PDB: 1GZX). For more information, see the article by Natarajan et al. (pp. 3839–3850). Artwork Image courtesy of C. Natarajan.

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Editorial
Review Articles
Research Articles
Expression of Concern

Editorial

Current and emerging roles of adipose tissue in health and disease

Emilio P. Mottillo; Gregory R. Steinberg

Biochem J (2020) 477 (19): 3645–3647.

Extract

View Articletitled, Current and emerging roles of adipose tissue in health and disease

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Review Articles

Exploiting S-nitrosylation for cancer therapy: facts and perspectives

Salvatore Rizza; Giuseppe Filomeni

Biochem J (2020) 477 (19): 3649–3672.

Abstract

View Articletitled, Exploiting S-nitrosylation for cancer therapy: facts and perspectives

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Genetic activity during early plant embryogenesis

Ran Tian; Priyanka Paul; Sanjay Joshi; Sharyn E. Perry

Biochem J (2020) 477 (19): 3743–3767.

Abstract

View Articletitled, Genetic activity during early plant embryogenesis

Supplementary data

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The transport mechanism of P4 ATPase lipid flippases

Rosa L. López-Marqués; Pontus Gourdon; Thomas Günther Pomorski; Michael Palmgren

Biochem J (2020) 477 (19): 3769–3790.

Abstract

View Articletitled, The transport mechanism of P4 ATPase lipid flippases

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Research Articles

Three cytosolic NAD-malate dehydrogenase isoforms of Arabidopsis thaliana: on the crossroad between energy fluxes and redox signaling

Aleksandra Liszka; Regina Schimpf; Krupskaya Ivannova Cartuche Zaruma; Annika Buhr; Thorsten Seidel; Stefan Walter; Johannes Knuesting; Anna Dreyer; Karl-Josef Dietz; Renate Scheibe; Jennifer Selinski

Biochem J (2020) 477 (19): 3673–3693.

Abstract

View Articletitled, Three cytosolic NAD-malate dehydrogenase isoforms of Arabidopsis thaliana: on the crossroad between energy fluxes and redox signaling

Supplementary data

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Structure based virtual screening identifies small molecule effectors for the sialoglycan binding protein Hsa

Rupesh Agarwal; Barbara A. Bensing; Dehui Mi; Paige N. Vinson; Jerome Baudry; Tina M. Iverson; Jeremy C. Smith

Biochem J (2020) 477 (19): 3695–3707.

Abstract

View Articletitled, Structure based virtual screening identifies small molecule effectors for the sialoglycan binding protein Hsa

Supplementary data

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The thiol oxidation-based sensing and regulation mechanism for the OasR-mediated organic peroxide and antibiotic resistance in C. glutamicum

Meiru Si; Can Chen; Chengchuan Che; Yang Liu; Xiaona Li; Tao Su

Biochem J (2020) 477 (19): 3709–3727.

Abstract

View Articletitled, The thiol oxidation-based sensing and regulation mechanism for the OasR-mediated organic peroxide and antibiotic resistance in C. glutamicum

Supplementary data

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Mechanisms of detoxification of high copper concentrations by the microalga Chlorella sorokiniana

Snežana Vojvodić; Marina Stanić; Bernd Zechmann; Tanja Dučić; Milan Žižić; Milena Dimitrijević; Jelena Danilović Luković; Milica R. Milenković; Jon K. Pittman; Ivan Spasojević

Biochem J (2020) 477 (19): 3729–3741.

Abstract

View Articletitled, Mechanisms of detoxification of high copper concentrations by the microalga Chlorella sorokiniana

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Biochemical and NMR characterization of the interactions of Vav2–SH2 domain with lipids and the EphA2 juxtamembrane region on membrane

Liang Ge; Bo Wu; Youjia Zhang; Jiarong Wang; Hongxin Zhao; Junfeng Wang

Biochem J (2020) 477 (19): 3791–3801.

Abstract

View Articletitled, Biochemical and NMR characterization of the interactions of Vav2–SH2 domain with lipids and the EphA2 juxtamembrane region on membrane

Supplementary data

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SUMO E3 ligase CBX4 regulates hTERT-mediated transcription of CDH1 and promotes breast cancer cell migration and invasion

Sulagna Sanyal; Payel Mondal; Sabyasachi Sen; Sumita Sengupta (Bandyopadhyay); Chandrima Das

Biochem J (2020) 477 (19): 3803–3818.

Abstract

View Articletitled, SUMO E3 ligase CBX4 regulates hTERT-mediated transcription of CDH1 and promotes breast cancer cell migration and invasion

Supplementary data

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X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2

Emilia M. Marijanovic; Karolina Weronika Swiderska; James Andersen; Jasmin C. Aschenbrenner; Chaille T. Webb; Marcin Drag; Nyssa Drinkwater; Sheena McGowan

Biochem J (2020) 477 (19): 3819–3832.

Abstract

View Articletitled, X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2

Supplementary data

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Structural insight into HEMK2–TRMT112-mediated glutamine methylation

Jie Gao; Bin Wang; Huijuan Yu; Gao Wu; Cuihong Wan; Wenting Liu; Shanhui Liao; Liansheng Cheng; Zhongliang Zhu

Biochem J (2020) 477 (19): 3833–3838.

Abstract

View Articletitled, Structural insight into HEMK2–TRMT112-mediated glutamine methylation

Supplementary data

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Effect of NH₂-terminal acetylation on the oxygenation properties of vertebrate haemoglobin

Chandrasekhar Natarajan; Anthony V. Signore; Vikas Kumar; Roy E. Weber; Angela Fago; Jay F. Storz

Biochem J (2020) 477 (19): 3839–3850.

Abstract

View Articletitled, Effect of NH2-terminal acetylation on the oxygenation properties of vertebrate haemoglobin

Supplementary data

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ShNPSN11, a vesicle-transport-related gene, confers disease resistance in tomato to Oidium neolycopersici

Qinggui Lian; Yanan Meng; Xinbei Zhao; Yuanliu Xu; Yang Wang; Brad Day; Qing Ma

Biochem J (2020) 477 (19): 3851–3866.

Abstract

View Articletitled, ShNPSN11, a vesicle-transport-related gene, confers disease resistance in tomato to Oidium neolycopersici

Supplementary data

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Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice

Sathish Sivaprakasam; Bojana Ristic; Nithya Mudaliar; Abdul N. Hamood; Jane Colmer-Hamood; Mitchell S. Wachtel; Anna G. Nevels; Kameswara R. Kottapalli; Vadivel Ganapathy

Biochem J (2020) 477 (19): 3867–3883.

Abstract

View Articletitled, Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice

Supplementary data

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Rubisco lysine acetylation occurs at very low stoichiometry in mature Arabidopsis leaves: implications for regulation of enzyme function

Brendan M. O'Leary; Andrew P. Scafaro; Ricarda Fenske; Owen Duncan; Elke Ströher; Jakob Petereit; A. Harvey Millar

Biochem J (2020) 477 (19): 3885–3896.

Abstract

View Articletitled, Rubisco lysine acetylation occurs at very low stoichiometry in mature Arabidopsis leaves: implications for regulation of enzyme function

Supplementary data

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Dopamine is an aryl hydrocarbon receptor agonist

Hyejin Park; Un-ho Jin; Keshav Karki; Arul Jayaraman; Clint Allred; Sharon K. Michelhaugh; Sandeep Mittal; Robert S. Chapkin; Stephen Safe

Biochem J (2020) 477 (19): 3899–3910.

Abstract

View Articletitled, Dopamine is an aryl hydrocarbon receptor agonist

Supplementary data

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Characterization of Streptococcus pneumoniae PriA helicase and its ATPase and unwinding activities in DNA replication restart

Min-Guan Lin; Yi-Ching Li; Chwan-Deng Hsiao

Biochem J (2020) 477 (19): 3911–3922.

Abstract

View Articletitled, Characterization of Streptococcus pneumoniae PriA helicase and its ATPase and unwinding activities in DNA replication restart

Supplementary data

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Expression of Concern

Expression of Concern: Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies

Biochem J (2020) 477 (19): 3897.

Extract

View Articletitled, Expression of Concern: Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies

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Trypanosomatid histones: the building blocks of the epigenetic code of highly divergent eukaryotes

Insights into the cellular function and mechanism of action of quinone reductase 2 (NQO2)

Effect of methyl DNA adducts on 3’-5’ exonuclease activity of human TREX1

Signalling by co-operative higher-order assembly formation: linking evidence at molecular and cellular levels

Aldose reductase, fructose and fat production in the liver

Editorial

Current and emerging roles of adipose tissue in health and disease

Review Articles

Exploiting S-nitrosylation for cancer therapy: facts and perspectives

Genetic activity during early plant embryogenesis

The transport mechanism of P4 ATPase lipid flippases

Research Articles

Three cytosolic NAD-malate dehydrogenase isoforms of Arabidopsis thaliana: on the crossroad between energy fluxes and redox signaling

Structure based virtual screening identifies small molecule effectors for the sialoglycan binding protein Hsa

The thiol oxidation-based sensing and regulation mechanism for the OasR-mediated organic peroxide and antibiotic resistance in C. glutamicum

Mechanisms of detoxification of high copper concentrations by the microalga Chlorella sorokiniana

Biochemical and NMR characterization of the interactions of Vav2–SH2 domain with lipids and the EphA2 juxtamembrane region on membrane

SUMO E3 ligase CBX4 regulates hTERT-mediated transcription of CDH1 and promotes breast cancer cell migration and invasion

X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2

Structural insight into HEMK2–TRMT112-mediated glutamine methylation

Effect of NH₂-terminal acetylation on the oxygenation properties of vertebrate haemoglobin

ShNPSN11, a vesicle-transport-related gene, confers disease resistance in tomato to Oidium neolycopersici

Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice

Rubisco lysine acetylation occurs at very low stoichiometry in mature Arabidopsis leaves: implications for regulation of enzyme function

Dopamine is an aryl hydrocarbon receptor agonist

Characterization of Streptococcus pneumoniae PriA helicase and its ATPase and unwinding activities in DNA replication restart

Expression of Concern

Expression of Concern: Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies

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