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Issues
December 2020
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Cover Image
Cover Image
The cover image shows a word cloud based on the findings of the review article by Fulcher and Sapkota (pp. 4397–4423) in this issue, depicting the many biological functions and modes of regulation of the CK1 family of Ser/Thr protein kinases. Image created by Luke Fulcher.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Deep learning and generative methods in cheminformatics and chemical biology: navigating small molecule space intelligently
Biochem J (2020) 477 (23): 4559–4580.
Functions and regulation of the serine/threonine protein kinase CK1 family: moving beyond promiscuity
Biochem J (2020) 477 (23): 4603–4621.
Research Articles
Methylation of two-component response regulator MtrA in mycobacteria negatively modulates its DNA binding and transcriptional activation
Anshika Singhal; Richa Virmani; Saba Naz; Gunjan Arora; Mohita Gaur; Parijat Kundu; Andaleeb Sajid; Richa Misra; Ankita Dabla; Suresh Kumar; Jacob Nellissery; Virginie Molle; Ulf Gerth; Anand Swaroop; Kirti Sharma; Vinay K. Nandicoori; Yogendra Singh
Biochem J (2020) 477 (23): 4473–4489.
PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability
Sandra M. Martín-Guerrero; Pedro Casado; Maruan Hijazi; Vinothini Rajeeve; Julio Plaza-Díaz; Francisco Abadía-Molina; Julio Navascués; Miguel A. Cuadros; Pedro R. Cutillas; David Martín-Oliva
Biochem J (2020) 477 (23): 4491–4513.
The biophysical basis of receptor tyrosine kinase ligand functional selectivity: Trk-B case study
Biochem J (2020) 477 (23): 4515–4526.
Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis
Biochem J (2020) 477 (23): 4527–4541.
Translesion synthesis of the major nitrogen mustard-induced DNA lesion by human DNA polymerase η
Biochem J (2020) 477 (23): 4543–4558.
Amyloid-beta oligomers induce Parkin-mediated mitophagy by reducing Miro1
Biochem J (2020) 477 (23): 4581–4597.
Structure of the FERM domain of a neural scaffold protein FRMPD4 implicated in X-linked intellectual disability
Biochem J (2020) 477 (23): 4623–4634.
Mg-protoporphyrin IX monomethyl ester cyclase from Rhodobacter capsulatus: radical SAM-dependent synthesis of the isocyclic ring of bacteriochlorophylls
Milan Wiesselmann; Stefanie Hebecker; José M. Borrero-de Acuña; Manfred Nimtz; David Bollivar; Lothar Jänsch; Jürgen Moser; Dieter Jahn
Biochem J (2020) 477 (23): 4635–4654.
Correction
Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue
Nusrat Hussain; Sheng-Ju Chuang; Manuel Johanns; Didier Vertommen; Gregory R. Steinberg; Bruce E. Kemp; Mark H. Rider
Biochem J (2020) 477 (23): 4599–4601.