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Issues
November 2021
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Cover Image
Cover Image
The dimeric reaction centre light-harvesting 1 (RC-LH1) core complex of Rhodobacter sphaeroides converts absorbed light energy to a charge separation, and then it reduces a quinone electron and proton acceptor to a quinol. In this issue, Qian and colleagues (pp. 3923–3937) investigate the dimerisation interface between two RC-LH1 monomers, and determine the cryogenic electron microscopy structure of the dimeric complex at 2.9 Å resolution. The cover image shows the role of PufX in imposing a bent conformation on the RC-LH1 dimer complex. The top view is of the cytoplasmic side of the membrane and the bottom view is in the plane of the membrane. Image courtesy of C. Neil Hunter.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Revisiting the contribution of mitochondrial biology to the pathophysiology of skeletal muscle insulin resistance
Biochem J (2021) 478 (21): 3809–3826.
Research Articles
Thermostability-based binding assays reveal complex interplay of cation, substrate and lipid binding in the bacterial DASS transporter, VcINDY
Biochem J (2021) 478 (21): 3847–3867.
Higher expression of proline dehydrogenase altered mitochondrial function and increased Trypanosoma cruzi differentiation in vitro and in the insect vector
Brian S. Mantilla; Lisvane Paes-Vieira; Felipe de Almeida Dias; Simone G. Calderano; Maria Carolina Elias; Daniela Cosentino-Gomes; Pedro L. Oliveira; José Roberto Meyer-Fernandes; Ariel M. Silber
Biochem J (2021) 478 (21): 3891–3903.
IFIT3 (interferon induced protein with tetratricopeptide repeats 3) modulates STAT1 expression in small extracellular vesicles
Biochem J (2021) 478 (21): 3905–3921.
Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 Å: the structural basis for dimerisation
Pu Qian; Tristan I. Croll; Andrew Hitchcock; Philip J. Jackson; Jack H. Salisbury; Pablo Castro-Hartmann; Kasim Sader; David J.K. Swainsbury; C. Neil Hunter
Biochem J (2021) 478 (21): 3923–3937.
A conserved NAG motif is critical to the catalytic activity of galactinol synthase, a key regulatory enzyme of RFO biosynthesis
Biochem J (2021) 478 (21): 3939–3955.
Expression and function of SLC38A5, an amino acid-coupled Na+/H+ exchanger, in triple-negative breast cancer and its relevance to macropinocytosis
Sabarish Ramachandran; Souad R. Sennoune; Monica Sharma; Muthusamy Thangaraju; Varshini V. Suresh; Tyler Sneigowski; Yangzom D. Bhutia; Kevin Pruitt; Vadivel Ganapathy
Biochem J (2021) 478 (21): 3957–3976.
