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February 2021
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Cover Image
LRRK1 and LRRK2 are regulated by differing upstream signals and phosphorylate distinct Rab GTPases. You can read more about this in the article by Malik and colleagues (pp. 553–578) in this issue. Image provided by Dario R. Alessi.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood–brain barrier
Biochem J (2021) 478 (3): 463–486.
Reprogramming the tumor metastasis cascade by targeting galectin-driven networks
Biochem J (2021) 478 (3): 597–617.
Commentaries
Simultaneous detection of reciprocal interactions between calmodulin, Ca2+ and molecular targets: a focus on the calmodulin-RyR2 complex
Biochem J (2021) 478 (3): 487–491.
Research Articles
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Asad U. Malik; Athanasios Karapetsas; Raja S. Nirujogi; Sebastian Mathea; Deep Chatterjee; Prosenjit Pal; Pawel Lis; Matthew Taylor; Elena Purlyte; Robert Gourlay; Mark Dorward; Simone Weidlich; Rachel Toth; Nicole K. Polinski; Stefan Knapp; Francesca Tonelli; Dario R. Alessi
Biochem J (2021) 478 (3): 553–578.
A conserved, buried cysteine near the P-site is accessible to cysteine modifications and increases ROS stability in the P-type plasma membrane H+-ATPase
Marcel Welle; Jesper T. Pedersen; Tina Ravnsborg; Maki Hayashi; Sandra Maaß; Dörte Becher; Ole N. Jensen; Christine Stöhr; Michael Palmgren
Biochem J (2021) 478 (3): 619–632.
A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner
Franziska Kopietz; Yazeed Alshuweishi; Silvia Bijland; Fatmah Alghamdi; Eva Degerman; Kei Sakamoto; Ian P. Salt; Olga Göransson
Biochem J (2021) 478 (3): 633–646.
A pipeline to evaluate inhibitors of the Pseudomonas aeruginosa exotoxin U
Daniel M. Foulkes; Keri McLean; Yalin Zheng; Joscelyn Sarsby; Atikah S. Haneef; David G. Fernig; Craig Winstanley; Neil Berry; Stephen B. Kaye
Biochem J (2021) 478 (3): 647–668.