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Issues
March 2021
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Cover Image
Cover Image
Srivastava and colleagues (pp. 1117–1136) report the crystal structure of histone chaperone anti silencing function 1 (Asf1) from Plasmodium falciparum. Asf1 is a central histone chaperone specific for histone H3 and H4. Biochemical characterization established conserved function of PfAsf1 as a histone H3 and H4 chaperone. The cover image shows the surface representation derived from high resolution X-ray crystal structure of PfAsf1 which indicates the existence of PfAsf1 in a dimeric state in the crystallographic asymmetric unit. Image courtesy of Siddhartha Roy.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Altered intestinal epithelial nutrient transport: an underappreciated factor in obesity modulated by diet and microbiota
Biochem J (2021) 478 (5): 975–995.
Eukaryotic protein uS19: a component of the decoding site of ribosomes and a player in human diseases
Biochem J (2021) 478 (5): 997–1008.
Research Articles
Structural basis of a chemokine heterodimer binding to glycosaminoglycans
Biochem J (2021) 478 (5): 1009–1021.
Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps
Hideaki Sato; Masakazu Sugishima; Mai Tsukaguchi; Takahiro Masuko; Mikuru Iijima; Mitsunori Takano; Yoshiaki Omata; Kei Hirabayashi; Kei Wada; Yoshio Hisaeda; Ken Yamamoto
Biochem J (2021) 478 (5): 1023–1042.
Unusual ring D fixation by three crucial residues promotes phycoviolobilin formation in the DXCF-type cyanobacteriochrome without the second Cys
Biochem J (2021) 478 (5): 1043–1059.
Structural insights into histone chaperone Asf1 and its characterization from Plasmodium falciparum
Biochem J (2021) 478 (5): 1117–1136.
Simultaneous targeting of CD44 and MMP9 catalytic and hemopexin domains as a therapeutic strategy
Biochem J (2021) 478 (5): 1139–1157.
Resveratrol promotes lysosomal function via ER calcium-dependent TFEB activation to ameliorate lipid accumulation
Biochem J (2021) 478 (5): 1159–1173.
Commentaries
Promiscuous enzymes generating d-amino acids in mammals: Why they may still surprise us?
Biochem J (2021) 478 (5): 1175–1178.
