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Issues
April 2021
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Cover Image
Cover Image
Serine pyrophosphorylation by the inositol pyrophosphate 5-IP7 keeps cellular MYC levels in check. Elevation in MYC downstream to 5-IP7 depletion influences cell fate in response to environmental cues. For further information see the article in this issue by Lolla and colleagues (pp. 1647–1661). Image was created by Akruti Shah using BioRender.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Classification, structural biology, and applications of mucin domain-targeting proteases
Biochem J (2021) 478 (8): 1585–1603.
Commentaries
Perspective
Research Articles
Synergy and allostery in ligand binding by HIV-1 Nef
Abdullah Aldehaiman; Afaque A. Momin; Audrey Restouin; Luyao Wang; Xiaoli Shi; Safia Aljedani; Sandrine Opi; Adrien Lugari; Umar F. Shahul Hameed; Luc Ponchon; Xavier Morelli; Mingdong Huang; Christian Dumas; Yves Collette; Stefan T. Arold
Biochem J (2021) 478 (8): 1525–1545.
Elongation factor eEF2 kinase and autophagy jointly promote survival of cancer cells
Biochem J (2021) 478 (8): 1547–1569.
A role for PAK1 mediated phosphorylation of β-catenin Ser552 in the regulation of insulin secretion
Biochem J (2021) 478 (8): 1605–1615.
Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis
Maria E. Solesio; Lihan Xie; Brendan McIntyre; Mathew Ellenberger; Erna Mitaishvili; Siddharth Bhadra-Lobo; Lisa F. Bettcher; Jason N. Bazil; Daniel Raftery; Ursula Jakob; Evgeny V. Pavlov
Biochem J (2021) 478 (8): 1631–1646.
Inositol pyrophosphates promote MYC polyubiquitination by FBW7 to regulate cell survival
Biochem J (2021) 478 (8): 1647–1661.