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Issues
June 2022
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Cover Image
Cover Image
The cover image shows the crystal structure of AMPK a2b1g1 complexed with the pan activator MSG011. The inset surface representation details architecture of the MSG011 binding site, formed between the AMPK alpha-kinase domain (green) and beta-carbohydrate binding module (CBM, cyan). Explore more with Ovens and colleagues, “Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator” on pages 1181-1204.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Perspective
Towards ‘end-to-end’ analysis and understanding of biological timecourse data
Biochem J (2022) 479 (11): 1257–1263.
Review Articles
NUCKS1 is a highly modified, chromatin-associated protein involved in a diverse set of biological and pathophysiological processes
Biochem J (2022) 479 (11): 1205–1220.
Commentaries
Research Articles
Characterization of uridine-cytidine kinase like-1 nucleoside kinase activity and its role in tumor growth
Biochem J (2022) 479 (11): 1149–1164.
Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator
Ashley J. Ovens; Yi Sing Gee; Naomi X.Y. Ling; Dingyi Yu; Justin P. Hardee; Jin D. Chung; Kevin R.W. Ngoei; Nicholas J. Waters; Nolan J. Hoffman; John W. Scott; Kim Loh; Katrin Spengler; Regine Heller; Michael W. Parker; Gordon S. Lynch; Fei Huang; Sandra Galic; Bruce E. Kemp; Jonathan B. Baell; Jonathan S. Oakhill; Christopher G. Langendorf
Biochem J (2022) 479 (11): 1181–1204.
Insight into the function of a unique voltage-sensor protein (TMEM266) and its short form in mouse cerebellum
Takafumi Kawai; Hirotaka Narita; Kohtarou Konno; Sharmin Akter; Rizki Tsari Andriani; Hirohide Iwasaki; Shoji Nishikawa; Norihiko Yokoi; Yuko Fukata; Masaki Fukata; Pattama Wiriyasermkul; Pornparn Kongpracha; Shushi Nagamori; Keizo Takao; Tsuyoshi Miyakawa; Manabu Abe; Kenji Sakimura; Masahiko Watanabe; Atsushi Nakagawa; Yasushi Okamura
Biochem J (2022) 479 (11): 1127–1145.
Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4+ T-cell proliferation and glycolytic activity under hypoxia and normoxia
Jonas A. Wik; Azazul Chowdhury; Shrikant Kolan; Nasser E. Bastani; Gaoyang Li; Kazi Alam; Franco Grimolizzi; Bjørn S. Skålhegg
Biochem J (2022) 479 (11): 1221–1235.
Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate
Xiaowen Duan; Dougall M. Norris; Sean J. Humphrey; Pengyi Yang; Kristen C. Cooke; Will P. Bultitude; Benjamin L. Parker; Olivia J. Conway; James G. Burchfield; James R. Krycer; Frances M. Brodsky; David E. James; Daniel J. Fazakerley
Biochem J (2022) 479 (11): 1237–1256.
