Issues

The cover image shows a conserved set of residues mediates dimerization and activation, via trans-autophosphorylation, for the MST family of kinases. Displayed are three different dimers of MST kinases that are compatible with trans-autophosphorylation. For each dimer, one kinase is coloured orange and the other blue. The conserved residues, which constitute the alpha-G helix, are highlighted. For more details se the article by Weingartner and colleagues (pp. 1165–1182) in this issue. The image is provided by Jennifer Kavran.