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The cover image is a fluorescent microscopy image showing colocalization of HA-GFP -NPT2A Arg495Cys (green) with FLAG-NHERF1 (red) in OK cells. Treatment with PTH does not change NPT2A Arg495Cys-NHERF1 colocalization at the apical membrane. For more information see the article by Sneddon and colleagues (pp. 685–699) in this issue. The image was provided by Tatyana Mamonova.
In this Issue
Overexpression of ARM repeat/U-box containing E3 ligase, PUB2 positively regulates growth and oxidative stress response in Arabidopsis
Lokesh K. Saini; Manisha Sharma; Barkha Ravi; Soma Ghosh; Sonam Pahuja; Nidhi Singh; Girdhar K. Pandey
Biochem J (2023) 480 (9): 555–571.
Genotoxic effects of the major alkylation damage N7-methylguanine and methyl formamidopyrimidine
Biochem J (2023) 480 (9): 573–585.
ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1
Kathryn Balmanno; Andrew M. Kidger; Dominic P. Byrne; Matthew J. Sale; Nejma Nassman; Patrick A. Eyers; Simon J. Cook
Biochem J (2023) 480 (9): 587–605.
Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module
Biochem J (2023) 480 (9): 629–647.
Mutagenic incorporation of inosine into DNA via T:I mismatch formation by human DNA polymerase eta (polη)
Biochem J (2023) 480 (9): 649–664.
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase
Catia L. Pierotti; Annette V. Jacobsen; Christoph Grohmann; Ruby K. Dempsey; Nima Etemadi; Joanne M. Hildebrand; Cheree Fitzgibbon; Samuel N. Young; Katherine A. Davies; Wilhelmus J. A. Kersten; John Silke; Kym N. Lowes; Hélène Jousset Sabroux; David C. S. Huang; Mark F. van Delft; James M. Murphy; Guillaume Lessene
Biochem J (2023) 480 (9): 665–684.
Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia
Biochem J (2023) 480 (9): 685–699.
LRRC8A is responsible for exosome biogenesis and volume regulation in colon cancer cells
Haifeng Zhang; Shiyu Cui; Zhenghui Jing; Guodan Fu; Rong Liu; Wenbao Zhao; Liting Xu; Lei Yu; Yuhui Bai; Changsheng Lv; Min Wu; Yuan Wei; Liangming Li; Shuang Peng
Biochem J (2023) 480 (9): 701–713.