1-9 of 9
Andrew W. MUNRO
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Human P450-like oxidation of diverse proton pump inhibitor drugs by ‘gatekeeper’ mutants of flavocytochrome P450 BM3

Available to Purchase
Christopher F. Butler, Caroline Peet, Kirsty J. McLean, Michael T. Baynham, Richard T. Blankley, Karl Fisher, Stephen E. J. Rigby, David Leys, Michael W. Voice, Andrew W. Munro
Journal: Biochemical Journal
Biochem J (2014) 460 (2): 247–259.
https://doi.org/10.1042/BJ20140030
Published: 13 May 2014
View articletitled, Human P450-like oxidation of diverse proton pump inhibitor drugs by ‘gatekeeper’ mutants of flavocytochrome P450 BM3
Open the PDF for Human P450-like oxidation of diverse proton pump inhibitor drugs by ‘gatekeeper’ mutants of flavocytochrome P450 BM3 in another window
Includes: Supplementary data
Articles

Glutamate–haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3

Available to Purchase
Hazel M. Girvan, Colin W. Levy, Paul Williams, Karl Fisher, Myles R. Cheesman, Stephen E. J. Rigby, David Leys, Andrew W. Munro
Journal: Biochemical Journal
Biochem J (2010) 427 (3): 455–466.
https://doi.org/10.1042/BJ20091603
Published: 14 April 2010
View articletitled, Glutamate–haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3
Open the PDF for Glutamate–haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3 in another window
Includes: Supplementary data
Articles

Novel haem co-ordination variants of flavocytochrome P450 BM3

Available to Purchase
Hazel M. Girvan, Helen S. Toogood, Rachael E. Littleford, Harriet E. Seward, W. Ewen Smith, Idorenyin S. Ekanem, David Leys, Myles R. Cheesman, Andrew W. Munro
Journal: Biochemical Journal
Biochem J (2009) 417 (1): 65–80.
https://doi.org/10.1042/BJ20081133
Published: 12 December 2008
View articletitled, Novel haem co-ordination variants of flavocytochrome P450 BM3
Open the PDF for Novel haem co-ordination variants of flavocytochrome P450 BM3 in another window
Includes: Supplementary data
Articles

Characterization of coenzyme binding and selectivity determinants in Mycobacterium tuberculosis flavoprotein reductase A: analysis of Arg 199 and Arg 200 mutants at the NADP(H) 2′-phosphate binding site

Available to Purchase
Muna Sabri, Adrian J. Dunford, Kirsty J. McLean, Rajasekhar Neeli, Nigel S. Scrutton, David Leys, Andrew W. Munro
Journal: Biochemical Journal
Biochem J (2009) 417 (1): 103–114.
https://doi.org/10.1042/BJ20080466
Published: 12 December 2008
View articletitled, Characterization of coenzyme binding and selectivity determinants in Mycobacterium tuberculosis flavoprotein reductase A: analysis of Arg 199 and Arg 200 mutants at the NADP(H) 2′-phosphate binding site
Open the PDF for Characterization of coenzyme binding and selectivity determinants in Mycobacterium tuberculosis flavoprotein reductase A: analysis of Arg 199 and Arg 200 mutants at the NADP(H) 2′-phosphate binding site in another window
Includes: Supplementary data
Articles

Trp 359 regulates flavin thermodynamics and coenzyme selectivity in Mycobacterium tuberculosis FprA

Available to Purchase
Rajasekhar Neeli, Muna Sabri, Kirsty J. McLean, Adrian J. Dunford, Nigel S. Scrutton, David Leys, Andrew W. Munro
Journal: Biochemical Journal
Biochem J (2008) 411 (3): 563–570.
https://doi.org/10.1042/BJ20071298
Published: 14 April 2008
View articletitled, Trp 359 regulates flavin thermodynamics and coenzyme selectivity in Mycobacterium tuberculosis FprA
Open the PDF for Trp 359 regulates flavin thermodynamics and coenzyme selectivity in Mycobacterium tuberculosis FprA in another window
Includes: Supplementary data
Articles

Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA

Available to Purchase
Kirsty J. McLEAN, Nigel S. SCRUTTON, Andrew W. MUNRO
Journal: Biochemical Journal
Biochem J (2003) 372 (2): 317–327.
https://doi.org/10.1042/bj20021692
Published: 01 June 2003
View articletitled, Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA
Open the PDF for Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA in another window
Articles

Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin

Available to Purchase
Daniel H. CRAIG, Terez BARNA, Peter C. E. MOODY, Neil C. BRUCE, Stephen K. CHAPMAN, Andrew W. MUNRO, Nigel S. SCRUTTON
Journal: Biochemical Journal
Biochem J (2001) 359 (2): 315–323.
https://doi.org/10.1042/bj3590315
Published: 08 October 2001
View articletitled, Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin
Open the PDF for Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin in another window
Articles

Probing the NADPH-binding site of Escherichia coli flavodoxin oxidoreductase

Available to Purchase
Claire LEADBEATER, Lisa MCIVER, Dominic J. CAMPOPIANO, Scott P. WEBSTER, Robert L. BAXTER, Sharon M. KELLY, Nicholas C. PRICE, Dominikus A. LYSEK, Michael A. NOBLE, Stephen K. CHAPMAN, Andrew W. MUNRO
Journal: Biochemical Journal
Biochem J (2000) 352 (2): 257–266.
https://doi.org/10.1042/bj3520257
Published: 24 November 2000
View articletitled, Probing the NADPH-binding site of Escherichia coli flavodoxin oxidoreductase
Open the PDF for Probing the NADPH-binding site of Escherichia coli flavodoxin oxidoreductase in another window
Articles

Roles of key active-site residues in flavocytochrome P450 BM3

Available to Purchase
Michael A. NOBLE, Caroline S. MILES, Stephen K. CHAPMAN, Dominikus A. LYSEK, Angela C. MACKAY, Graeme A. REID, Robert P. HANZLIK, Andrew W. MUNRO
Journal: Biochemical Journal
Biochem J (1999) 339 (2): 371–379.
https://doi.org/10.1042/bj3390371
Published: 08 April 1999
View articletitled, Roles of key active-site residues in flavocytochrome P450 BM3
Open the PDF for Roles of key active-site residues in flavocytochrome P450 BM3 in another window