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Bengt MANNERVIK
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Articles

Multidimensional epistasis and fitness landscapes in enzyme evolution

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Wei Zhang, Daniel F. A. R. Dourado, Pedro Alexandrino Fernandes, Maria João Ramos, Bengt Mannervik
Journal: Biochemical Journal
Biochem J (2012) 445 (1): 39–46.
https://doi.org/10.1042/BJ20120136
Published: 15 June 2012
View articletitled, Multidimensional epistasis and fitness landscapes in enzyme evolution
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Includes: Supplementary data
Articles

Porcine glutathione transferase Alpha 2-2 is a human GST A3-3 analogue that catalyses steroid double-bond isomerization

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Natalia Fedulova, Françoise Raffalli-Mathieu, Bengt Mannervik
Journal: Biochemical Journal
Biochem J (2010) 431 (1): 159–167.
https://doi.org/10.1042/BJ20100839
Published: 14 September 2010
View articletitled, Porcine glutathione transferase Alpha 2-2 is a human GST A3-3 analogue that catalyses steroid double-bond isomerization
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Includes: Supplementary data
Articles

Targeting human glutathione transferase A3-3 attenuates progesterone production in human steroidogenic cells

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Françoise Raffalli-Mathieu, Carolina Orre, Mats Stridsberg, Maryam Hansson Edalat, Bengt Mannervik
Journal: Biochemical Journal
Biochem J (2008) 414 (1): 103–109.
https://doi.org/10.1042/BJ20080397
Published: 29 July 2008
View articletitled, Targeting human glutathione transferase A3-3 attenuates progesterone production in human steroidogenic cells
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Articles

Residue 234 in glutathione transferase T1-1 plays a pivotal role in the catalytic activity and the selectivity against alternative substrates

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Abeer SHOKEER, Anna-Karin LARSSON, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (2005) 388 (1): 387–392.
https://doi.org/10.1042/BJ20042064
Published: 10 May 2005
View articletitled, Residue 234 in glutathione transferase T1-1 plays a pivotal role in the catalytic activity and the selectivity against alternative substrates
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Includes: Supplementary data
Articles

Kinetic properties of missense mutations in patients with glutathione synthetase deficiency

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Runa NJÅLSSON, Katarina CARLSSON, Birgit OLIN, Birgit CARLSSON, Lel WHITBREAD, Galina POLEKHINA, Michael W. PARKER, Svante NORGREN, Bengt MANNERVIK, Philip G. BOARD, Agne LARSSON
Journal: Biochemical Journal
Biochem J (2000) 349 (1): 275–279.
https://doi.org/10.1042/bj3490275
Published: 26 June 2000
View articletitled, Kinetic properties of missense mutations in patients with glutathione synthetase deficiency
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Articles

An approach to optimizing the active site in a glutathione transferase by evolution in vitro

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Lars O. HANSSON, Mikael WIDERSTEN, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (1999) 344 (1): 93–100.
https://doi.org/10.1042/bj3440093
Published: 08 November 1999
View articletitled, An approach to optimizing the active site in a glutathione transferase by evolution in vitro
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Articles

Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases

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Rachel HURST, Yongping BAO, Per JEMTH, Bengt MANNERVIK, Gary WILLIAMSON
Journal: Biochemical Journal
Biochem J (1998) 332 (1): 97–100.
https://doi.org/10.1042/bj3320097
Published: 15 May 1998
View articletitled, Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases
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Articles

Human glutathione transferase A4-4: an Alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation

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Ina HUBATSCH, Marianne RIDDERSTRÖM, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (1998) 330 (1): 175–179.
https://doi.org/10.1042/bj3300175
Published: 15 February 1998
View articletitled, Human glutathione transferase A4-4: an Alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation
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Articles

Mutagenesis of residue 157 in the active site of human glyoxalase I

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Marianne RIDDERSTRÖM, D. Alexander CAMERON, T. Alwyn JONES, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (1997) 328 (1): 231–235.
https://doi.org/10.1042/bj3280231
Published: 15 November 1997
View articletitled, Mutagenesis of residue 157 in the active site of human glyoxalase I
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Articles

Evidence for redox regulation of the transcription factor NtcA, acting both as an activator and a repressor, in the cyanobacterium Anabaena PCC 7120

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Fanyi JIANG, Bengt MANNERVIK, Birgitta BERGMAN
Journal: Biochemical Journal
Biochem J (1997) 327 (2): 513–517.
https://doi.org/10.1042/bj3270513
Published: 15 October 1997
View articletitled, Evidence for redox regulation of the transcription factor NtcA, acting both as an activator and a repressor, in the cyanobacterium Anabaena PCC 7120
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Articles

Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes

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Sofia BAEZ, Juan SEGURA-AGUILAR, Mikael WIDERSTEN, Ann-Sofie JOHANSSON, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (1997) 324 (1): 25–28.
https://doi.org/10.1042/bj3240025
Published: 15 May 1997
View articletitled, Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes
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Articles

Molecular cloning and characterization of the thiolesterase glyoxalase II from Arabidopsis thaliana

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Marianne RIDDERSTRÖM, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (1997) 322 (2): 449–454.
https://doi.org/10.1042/bj3220449
Published: 01 March 1997
View articletitled, Molecular cloning and characterization of the thiolesterase glyoxalase II from Arabidopsis thaliana
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Articles

Heterologous expression, purification and characterization of rat class theta glutathione transferase T2-2

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Per JEMTH, Gun STENBERG, Grigoriy CHAGA, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (1996) 316 (1): 131–136.
https://doi.org/10.1042/bj3160131
Published: 15 May 1996
View articletitled, Heterologous expression, purification and characterization of rat class theta glutathione transferase T2-2
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Articles

Optimized heterologous expression of the human zinc enzyme glyoxalase I

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Marianne ÖM, Bengt MANNERVIK
Journal: Biochemical Journal
Biochem J (1996) 314 (2): 463–467.
https://doi.org/10.1042/bj3140463
Published: 01 March 1996
View articletitled, Optimized heterologous expression of the human zinc enzyme glyoxalase I
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Articles

Probing the active site of glyoxalase I from human erythrocytes by use of the strong reversible inhibitor S - p -bromobenzylglutathione and metal substitutions

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Anne-Charlotte Aronsson, Siv Sellin, Gudrun Tibbelin, Bengt Mannervik
Journal: Biochemical Journal
Biochem J (1981) 197 (1): 67–75.
https://doi.org/10.1042/bj1970067
Published: 01 July 1981
View articletitled, Probing the active site of glyoxalase I from human erythrocytes by use of the strong reversible inhibitor S - p -bromobenzylglutathione and metal substitutions
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Articles

Comparison of glyoxalase I purified from yeast ( Saccharomyces cerevisiae ) with the enzyme from mammalian sources

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Ewa Marmstål, Anne-Charlotte Aronsson, Bengt Mannervik
Journal: Biochemical Journal
Biochem J (1979) 183 (1): 23–30.
https://doi.org/10.1042/bj1830023
Published: 01 October 1979
View articletitled, Comparison of glyoxalase I purified from yeast ( Saccharomyces cerevisiae ) with the enzyme from mammalian sources
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Articles

Characterization of glyoxalase I purified from pig erythrocytes by affinity chromatography

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Anne-Charlotte Aronsson, Bengt Mannervik
Journal: Biochemical Journal
Biochem J (1977) 165 (3): 503–509.
https://doi.org/10.1042/bj1650503
Published: 01 September 1977
View articletitled, Characterization of glyoxalase I purified from pig erythrocytes by affinity chromatography
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Articles

A steady-state kinetic model of butyrylcholinesterase from horse plasma

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Klas-Bertil Augustinsson, Tamas Bartfai, Bengt Mannervik
Journal: Biochemical Journal
Biochem J (1974) 141 (3): 825–834.
https://doi.org/10.1042/bj1410825
Published: 01 September 1974
View articletitled, A steady-state kinetic model of butyrylcholinesterase from horse plasma
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