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Bruce E. Kemp
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Articles

Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator

Ashley J. Ovens, Yi Sing Gee, Naomi X.Y. Ling, Dingyi Yu, Justin P. Hardee, Jin D. Chung, Kevin R.W. Ngoei, Nicholas J. Waters, Nolan J. Hoffman, John W. Scott, Kim Loh, Katrin Spengler, Regine Heller, Michael W. Parker, Gordon S. Lynch, Fei Huang, Sandra Galic, Bruce E. Kemp, Jonathan B. Baell, Jonathan S. Oakhill, Christopher G. Langendorf
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1181–1204.
https://doi.org/10.1042/BCJ20220067
Published: 08 June 2022
View article titled, Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator
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Includes: Supplementary data
Articles

AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue

Sheng-Ju Chuang, Manuel Johanns, Sébastien Pyr dit Ruys, Gregory R. Steinberg, Bruce E. Kemp, Benoît Viollet, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2021) 478 (21): 3869–3889.
https://doi.org/10.1042/BCJ20210411
Published: 09 November 2021
View article titled, AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue
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Includes: Supplementary data
Articles

Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Nusrat Hussain, Sheng-Ju Chuang, Manuel Johanns, Didier Vertommen, Gregory R. Steinberg, Bruce E. Kemp, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2020) 477 (23): 4599–4601.
https://doi.org/10.1042/BCJ-2019-0788_COR
Published: 08 December 2020
View article titled, Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue
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Articles

Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Nusrat Hussain, Sheng-Ju Chuang, Manuel Johanns, Didier Vertommen, Gregory R. Steinberg, Bruce E. Kemp, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2020) 477 (8): 1373–1389.
https://doi.org/10.1042/BCJ20190788
Published: 23 April 2020
View article titled, Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue
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Includes: Supplementary data
Articles

Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis

Andrew J. O’Brien, Linda A. Villani, Lindsay A. Broadfield, Vanessa P. Houde, Sandra Galic, Giovanni Blandino, Bruce E. Kemp, Theodoros Tsakiridis, Paola Muti, Gregory R. Steinberg
Journal: Biochemical Journal
Biochem J (2015) 469 (2): 177–187.
https://doi.org/10.1042/BJ20150122
Published: 06 July 2015
View article titled, Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis
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Articles

Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity

Rebecca J. Ford, Morgan D. Fullerton, Stephen L. Pinkosky, Emily A. Day, John W. Scott, Jonathan S. Oakhill, Adam L. Bujak, Brennan K. Smith, Justin D. Crane, Regje M. Blümer, Katarina Marcinko, Bruce E. Kemp, Hertzel C. Gerstein, Gregory R. Steinberg
Journal: Biochemical Journal
Biochem J (2015) 468 (1): 125–132.
https://doi.org/10.1042/BJ20150125
Published: 05 May 2015
View article titled, Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity
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Articles

Regulation of the renal-specific Na + –K + –2Cl − co-transporter NKCC2 by AMP-activated protein kinase (AMPK)

Scott A. Fraser, Ignacio Gimenez, Natasha Cook, Ian Jennings, Marina Katerelos, Frosa Katsis, Vicki Levidiotis, Bruce E. Kemp, David A. Power
Journal: Biochemical Journal
Biochem J (2007) 405 (1): 85–93.
https://doi.org/10.1042/BJ20061850
Published: 13 June 2007
View article titled, Regulation of the renal-specific Na + –K + –2Cl − co-transporter NKCC2 by AMP-activated protein kinase (AMPK)
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Articles

Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization

Michelle T. Fodero-Tavoletti, Matthew P. Hardy, Brent Cornell, Frosa Katsis, Christine M. Sadek, Christina A. Mitchell, Bruce E. Kemp, Tony Tiganis
Journal: Biochemical Journal
Biochem J (2005) 389 (2): 343–354.
https://doi.org/10.1042/BJ20041932
Published: 05 July 2005
View article titled, Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization
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Includes: Supplementary data
Articles

The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis

Patricia BUKCZYNSKA, Manuela KLINGLER-HOFFMANN, Kenneth I. MITCHELHILL, Mark H. C. LAM, Melissa CICCOMANCINI, Nicholas K. TONKS, Boris SARCEVIC, Bruce E. KEMP, Tony TIGANIS
Journal: Biochemical Journal
Biochem J (2004) 380 (3): 939–949.
https://doi.org/10.1042/bj20031780
Published: 15 June 2004
View article titled, The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis
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Includes: Supplementary data
Articles

Post-translational modifications of the β-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization

Scott M. WARDEN, Christine RICHARDSON, John O'DONNELL, Jr, David STAPLETON, Bruce E. KEMP, Lee A. WITTERS
Journal: Biochemical Journal
Biochem J (2001) 354 (2): 275–283.
https://doi.org/10.1042/bj3540275
Published: 22 February 2001
View article titled, Post-translational modifications of the β-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization
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Articles

Synapsins as major neuronal Ca 2+ /S100A1-interacting proteins

Jörg HEIERHORST, Ken I. MITCHELHILL, Richard J. MANN, Tony TIGANIS, Andrew J. CZERNIK, Paul GREENGARD, Bruce E. KEMP
Journal: Biochemical Journal
Biochem J (1999) 344 (2): 577–583.
https://doi.org/10.1042/bj3440577
Published: 24 November 1999
View article titled, Synapsins as major neuronal Ca 2+ /S100A1-interacting proteins
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