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Charles S. CRAIK
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Articles

Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor

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Vidhu Sharma, Preety Panwar, Anthony J. O’Donoghue, Haoran Cui, Rafael V. C. Guido, Charles S. Craik, Dieter Brömme
Journal: Biochemical Journal
Biochem J (2015) 465 (1): 163–173.
https://doi.org/10.1042/BJ20140809
Published: 12 December 2014
View articletitled, Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor
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Includes: Supplementary data
Articles

Human and mouse granzyme M display divergent and species-specific substrate specificities

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Stefanie A.H. de Poot, Marijn Westgeest, Daniel R. Hostetter, Petra van Damme, Kim Plasman, Kimberly Demeyer, Roel Broekhuizen, Kris Gevaert, Charles S. Craik, Niels Bovenschen
Journal: Biochemical Journal
Biochem J (2011) 437 (3): 431–442.
https://doi.org/10.1042/BJ20110210
Published: 13 July 2011
View articletitled, Human and mouse granzyme M display divergent and species-specific substrate specificities
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Includes: Supplementary data
Articles

Proteases as therapeutics

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Charles S. Craik, Michael J. Page, Edwin L. Madison
Journal: Biochemical Journal
Biochem J (2011) 435 (1): 1–16.
https://doi.org/10.1042/BJ20100965
Published: 15 March 2011
View articletitled, Proteases as therapeutics
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Includes: Supplementary data
Articles

Substrate specificity of transthyretin: identification of natural substrates in the nervous system

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Márcia A. Liz, Carolina E. Fleming, Ana F. Nunes, Maria R. Almeida, Fernando M. Mar, Youngchool Choe, Charles S. Craik, James C. Powers, Matthew Bogyo, Mónica M. Sousa
Journal: Biochemical Journal
Biochem J (2009) 419 (2): 467–474.
https://doi.org/10.1042/BJ20082090
Published: 27 March 2009
View articletitled, Substrate specificity of transthyretin: identification of natural substrates in the nervous system
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Articles

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers

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Sylvia Herter, Derek E. Piper, Wade Aaron, Timothy Gabriele, Gene Cutler, Ping Cao, Ami S. Bhatt, Youngchool Choe, Charles S. Craik, Nigel Walker, David Meininger, Timothy Hoey, Richard J. Austin
Journal: Biochemical Journal
Biochem J (2005) 390 (1): 125–136.
https://doi.org/10.1042/BJ20041955
Published: 09 August 2005
View articletitled, Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
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Includes: Supplementary data
Articles

The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase

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Christopher T. EGGERS, Iain A. MURRAY, Valerie A. DELMAR, Anthony G. DAY, Charles S. CRAIK
Journal: Biochemical Journal
Biochem J (2004) 379 (1): 107–118.
https://doi.org/10.1042/bj20031790
Published: 01 April 2004
View articletitled, The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase
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Articles

Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax

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Byoung-Kuk NA, Bhaskar R. SHENAI, Puran S. SIJWALI, Youngchool CHOE, Kailash C. PANDEY, Ajay SINGH, Charles S. CRAIK, Philip J. ROSENTHAL
Journal: Biochemical Journal
Biochem J (2004) 378 (2): 529–538.
https://doi.org/10.1042/bj20031487
Published: 01 March 2004
View articletitled, Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax
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Articles

Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII

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Barbara LEITING, KellyAnn D. PRYOR, Joseph K. WU, Frank MARSILIO, Reshma A. PATEL, Charles S. CRAIK, Jonathan A. ELLMAN, Richard T. CUMMINGS, Nancy A. THORNBERRY
Journal: Biochemical Journal
Biochem J (2003) 371 (2): 525–532.
https://doi.org/10.1042/bj20021643
Published: 15 April 2003
View articletitled, Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII
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Articles

Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites

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Ajay SINGH, Bhaskar R. SHENAI, Youngchool CHOE, Jiri GUT, Puran S. SIJWALI, Charles S. CRAIK, Philip J. ROSENTHAL
Journal: Biochemical Journal
Biochem J (2002) 368 (1): 273–281.
https://doi.org/10.1042/bj20020753
Published: 15 November 2002
View articletitled, Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites
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Articles

Bile pigments as HIV-1 protease inhibitors and their effects on HIV-1 viral maturation and infectivity in vitro

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Fiona McPHEE, Patricia S. CALDERA, Guy W. BEMIS, Antony F. McDONAGH, Irwin D. KUNTZ, Charles S. CRAIK
Journal: Biochemical Journal
Biochem J (1996) 320 (2): 681–686.
https://doi.org/10.1042/bj3200681
Published: 01 December 1996
View articletitled, Bile pigments as HIV-1 protease inhibitors and their effects on HIV-1 viral maturation and infectivity in vitro
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