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Determination of cytochrome P -448 activity in biological tissues

C E Phillipson, P M M Godden, P Y Lum, C Ioannides, D V Parke

Biochem J (1984) 221 (1): 81–88.

https://doi.org/10.1042/bj2210081

Published: 01 July 1984

View article titled, Determination of cytochrome P -448 activity in biological tissues

Articles

Studies on the substrate-binding sites of liver microsomal cytochrome P -448

C E Phillipson, C Ioannides, M Delaforge, D V Parke

Biochem J (1982) 207 (1): 51–56.

https://doi.org/10.1042/bj2070051

Published: 01 October 1982

View article titled, Studies on the substrate-binding sites of liver microsomal cytochrome P -448

Articles

The metabolic oxidation of the ethynyl group in 4-ethynylbiphenyl in vitro

A Wade, A M Symons, L Martin, D V Parke

Biochem J (1980) 188 (3): 867–872.

https://doi.org/10.1042/bj1880867

Published: 15 June 1980

View article titled, The metabolic oxidation of the ethynyl group in 4-ethynylbiphenyl in vitro

Articles

Metabolic oxidation of the ethynyl group in 4-ethynylbiphenyl

A Wade, A M Symons, L Martin, D V Parke

Biochem J (1979) 184 (3): 509–517.

https://doi.org/10.1042/bj1840509

Published: 15 December 1979

View article titled, Metabolic oxidation of the ethynyl group in 4-ethynylbiphenyl

Articles

The metabolism of shikimate in the rat

D Brewster, R S Jones, D V Parke

Biochem J (1978) 170 (2): 257–264.

https://doi.org/10.1042/bj1700257

Published: 15 February 1978

View article titled, The metabolism of shikimate in the rat

Articles

The metabolism of cyclohexanecarboxylate in the rat

D Brewster, R S Jones, D V Parke

Biochem J (1977) 164 (3): 595–600.

https://doi.org/10.1042/bj1640595

Published: 15 June 1977

View article titled, The metabolism of cyclohexanecarboxylate in the rat

Articles

Preparation of immobilized baker's-yeast glucose 6-phosphate dehydrogenase attached to modified sepharose and sephadex and a comparison of the properties of these preparations with those of the soluble enzyme

M A Goheer, B J Gould, D V Parke

Biochem J (1976) 157 (2): 289–294.

https://doi.org/10.1042/bj1570289

Published: 01 August 1976

View article titled, Preparation of immobilized baker's-yeast glucose 6-phosphate dehydrogenase attached to modified sepharose and sephadex and a comparison of the properties of these preparations with those of the soluble enzyme

Articles

The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes

F J. McPherson, J W. Bridges, D V. Parke

Biochem J (1976) 154 (3): 773–780.

https://doi.org/10.1042/bj1540773

Published: 15 March 1976

View article titled, The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes

Articles

A study of the possible metabolism of trichlorofluoromethane

P J Cox, L J King, D V Parke

Biochem J (1972) 130 (1): 13P–14P.

https://doi.org/10.1042/bj1300013Pb

Published: 01 November 1972

View article titled, A study of the possible metabolism of trichlorofluoromethane

Articles

Inhibition studies on the aromatization of androst-4-ene-3,17-dione by human placental microsomal preparations

J Chakraborty, R Hopkins, D V Parke

Biochem J (1972) 130 (1): 19P–20P.

https://doi.org/10.1042/bj1300019Pb

Published: 01 November 1972

View article titled, Inhibition studies on the aromatization of androst-4-ene-3,17-dione by human placental microsomal preparations

Articles

The effect of electro-convulsive therapy on the urinary excretion of adenosine 3':5'-cyclic monophosphate

K Hamadah, H Holmes, G Barker, G C Hartman, D V Parke

Biochem J (1972) 130 (1): 15P.

https://doi.org/10.1042/bj1300015Pa

Published: 01 November 1972

View article titled, The effect of electro-convulsive therapy on the urinary excretion of adenosine 3':5'-cyclic monophosphate

Articles

Effects of ethoxyquin on hepatic microsomal enzymes

D V Parke, A Rahm, R Walker

Biochem J (1972) 130 (2): 84P.

https://doi.org/10.1042/bj1300084P

Published: 01 November 1972

View article titled, Effects of ethoxyquin on hepatic microsomal enzymes

Articles

Spectral evidence for the presence of cytochrome P-450 in microsomal fractions obtained from some higher plants

A Markham, G C Hartman, D V Parke

Biochem J (1972) 130 (2): 90P.

https://doi.org/10.1042/bj1300090Pa

Published: 01 November 1972

View article titled, Spectral evidence for the presence of cytochrome P-450 in microsomal fractions obtained from some higher plants

Articles

Induction of aryl hydrocarbon hydroxylase in various tissues of the rat by methylenedioxyphenyl compounds

B G Lake, D V Parke

Biochem J (1972) 130 (2): 86P.

https://doi.org/10.1042/bj1300086P

Published: 01 November 1972

View article titled, Induction of aryl hydrocarbon hydroxylase in various tissues of the rat by methylenedioxyphenyl compounds

Articles

Mechanisms and consequences of the induction of microsomal enzymes of mammalian liver

D V Parke

Biochem J (1972) 130 (2): 53P–55P.

https://doi.org/10.1042/bj1300053P

Published: 01 November 1972

View article titled, Mechanisms and consequences of the induction of microsomal enzymes of mammalian liver

Articles

A comparison of the interactions of trichlorofluoromethane and carbon tetrachloride with hepatic cytochrome P-450

P J Cox, L J King, D V Parke

Biochem J (1972) 130 (2): 87P.

https://doi.org/10.1042/bj1300087Pa

Published: 01 November 1972

View article titled, A comparison of the interactions of trichlorofluoromethane and carbon tetrachloride with hepatic cytochrome P-450

Articles

The effect of carbenoxolone on the subcellular distribution of ( 3 H) aldosterone in rat kidney

M J Humphrey, W E Lindup, D V Parke, J Chakraborty

Biochem J (1972) 130 (2): 87P–88P.

https://doi.org/10.1042/bj1300087Pb

Published: 01 November 1972

View article titled, The effect of carbenoxolone on the subcellular distribution of ( 3 H) aldosterone in rat kidney

Articles

Biochemical and pathological differences in hepatic response to chronic feeding of safrole and butylated hydroxytoluene to rats

T J B Gray, D V Parke, P Grasso, R F Crampton

Biochem J (1972) 130 (2): 91P.

https://doi.org/10.1042/bj1300091P

Published: 01 November 1972

View article titled, Biochemical and pathological differences in hepatic response to chronic feeding of safrole and butylated hydroxytoluene to rats

Articles

Nitrosation of food amines under simulated stomach conditions

B E Newton, M J Saxby, C L Walters, D V Parke, R Walker

Biochem J (1972) 130 (2): 82P.

https://doi.org/10.1042/bj1300082Pa

Published: 01 November 1972

View article titled, Nitrosation of food amines under simulated stomach conditions

Articles

Gaseous products of the interaction of sodium nitrite with procine skeletal muscle

G Woolford, R J Casselden, C L Walters, D V parke, B J Gould

Biochem J (1972) 130 (2): 82P–83P.

https://doi.org/10.1042/bj1300082Pb

Published: 01 November 1972

View article titled, Gaseous products of the interaction of sodium nitrite with procine skeletal muscle

Articles

Interaction of safrole and isosafrole with hepatic microsomal haemoproteins

B G Lake, D V Parke

Biochem J (1972) 127 (2): 23P.

https://doi.org/10.1042/bj1270023Pa

Published: 01 April 1972

View article titled, Interaction of safrole and isosafrole with hepatic microsomal haemoproteins

Articles

Biological oxygenation of drugs and steroids in the placenta

J Chakraborty, R Hopkins, D V Parke

Biochem J (1971) 125 (2): 15P–16P.

https://doi.org/10.1042/bj1250015P

Published: 01 November 1971

View article titled, Biological oxygenation of drugs and steroids in the placenta

Articles

The effect of diet on rat plasma corticosteroids and liver aromatic hydroxylase activity

T K Basu, J W Dickerson, D V Parke

Biochem J (1971) 125 (2): 16P.

https://doi.org/10.1042/bj1250016Pa

Published: 01 November 1971

View article titled, The effect of diet on rat plasma corticosteroids and liver aromatic hydroxylase activity

Articles

Induction of a new hepatic microsomal haemoprotein by safrole and isosafrole

D V Parke, H Rahman

Biochem J (1971) 123 (2): 9P–10P.

https://doi.org/10.1042/bj1230009Pb

Published: 01 June 1971

View article titled, Induction of a new hepatic microsomal haemoprotein by safrole and isosafrole

Articles

The induction of hepatic microsomal enzymes by safrole

D V Parke, H Rahman

Biochem J (1970) 119 (5): 53P–54P.

https://doi.org/10.1042/bj1190053Pb

Published: 01 October 1970

View article titled, The induction of hepatic microsomal enzymes by safrole

Articles

The effects of development on the activity of drug-metabolizing enzymes in the liver of the rat

T K Basu, J W T Dickerson, D V Parke

Biochem J (1970) 119 (5): 54P.

https://doi.org/10.1042/bj1190054Pa

Published: 01 October 1970

View article titled, The effects of development on the activity of drug-metabolizing enzymes in the liver of the rat

Articles

The effects of some terpenoids and other dietary anutrients on hepatic drug-metabolizing enzymes

D V Parke, H Rahman

Biochem J (1969) 113 (2): 12P.

https://doi.org/10.1042/bj1130012Pa

Published: 01 June 1969

View article titled, The effects of some terpenoids and other dietary anutrients on hepatic drug-metabolizing enzymes

Articles

The effect of pregnancy on the hydroxylation and reduction of drugs and cytochrome P-450 content of rat liver microsomes

M G Neale, D V Parke

Biochem J (1969) 113 (2): 12P–13P.

https://doi.org/10.1042/bj1130012Pb

Published: 01 June 1969

View article titled, The effect of pregnancy on the hydroxylation and reduction of drugs and cytochrome P-450 content of rat liver microsomes

Articles

Studies in detoxication. 86. The metabolism of 14 C-labelled ethylene glycol

P. K. Gessner, D V Parke, R T Williams

Biochem J (1961) 79 (3): 482–489.

https://doi.org/10.1042/bj0790482

Published: 01 June 1961

View article titled, Studies in detoxication. 86. The metabolism of 14 C-labelled ethylene glycol

Articles

Studies in detoxication. 85. The metabolism of m -dinitro[ 14 C]benzene in the rabbit

D V Parke

Biochem J (1961) 78 (2): 262–271.

https://doi.org/10.1042/bj0780262

Published: 01 February 1961

View article titled, Studies in detoxication. 85. The metabolism of m -dinitro[ 14 C]benzene in the rabbit

Articles

Studies in detoxication. 84. The metabolism of [ 14 C]aniline in the rabbit and other animals

D. V. Parke

Biochem J (1960) 77 (3): 493–503.

https://doi.org/10.1042/bj0770493

Published: 01 December 1960

View article titled, Studies in detoxication. 84. The metabolism of [ 14 C]aniline in the rabbit and other animals

Articles

Studies in detoxication. 80. The metabolism of glycols

P. K. Gessner, D V Parke, R T Williams

Biochem J (1960) 74 (1): 1–5.

https://doi.org/10.1042/bj0740001

Published: 01 January 1960

View article titled, Studies in detoxication. 80. The metabolism of glycols

Articles

Studies in detoxication. 81. The metabolism of halogenobenzenes: ( a ) Penta- and hexa-chlorobenzenes. ( b ) Further observations on 1:3:5-trichlorobenzene

D V Parke, R T Williams

Biochem J (1960) 74 (1): 5–9.

https://doi.org/10.1042/bj0740005

Published: 01 January 1960

View article titled, Studies in detoxication. 81. The metabolism of halogenobenzenes: ( a ) Penta- and hexa-chlorobenzenes. ( b ) Further observations on 1:3:5-trichlorobenzene

Articles

Studies in detoxication. 79. The metabolism of cyclo [ 14 C]hexane and its derivatives

T H Elliott, D V Parke, R T Williams

Biochem J (1959) 72 (2): 193–200.

https://doi.org/10.1042/bj0720193

Published: 01 June 1959

View article titled, Studies in detoxication. 79. The metabolism of cyclo [ 14 C]hexane and its derivatives

Articles

Studies in detoxication. 77. The metabolism of phenylhydrazine and some phenylhydrazones

W. M. McIsaac, D. V. Parke, R. T. Williams

Biochem J (1958) 70 (4): 688–697.

https://doi.org/10.1042/bj0700688

Published: 01 December 1958

View article titled, Studies in detoxication. 77. The metabolism of phenylhydrazine and some phenylhydrazones

Articles

Studies in detoxication. 76. The metabolism of halogenobenzenes. 1:2:3:4-, 1:2:3:5- and 1:2:4:5-tetrachlorobenzenes

W. R. Jondorf, D. V. Parke, R. T. Williams

Biochem J (1958) 69 (2): 181–189.

https://doi.org/10.1042/bj0690181

Published: 01 June 1958

View article titled, Studies in detoxication. 76. The metabolism of halogenobenzenes. 1:2:3:4-, 1:2:3:5- and 1:2:4:5-tetrachlorobenzenes

Articles

Studies in detoxication. 68. The metabolism of [ 14 C]nitrobenzene in the rabbit and guinea pig

D. V. Parke

Biochem J (1956) 62 (2): 339–346.

https://doi.org/10.1042/bj0620339

Published: 01 February 1956

View article titled, Studies in detoxication. 68. The metabolism of [ 14 C]nitrobenzene in the rabbit and guinea pig

Articles

Studies in detoxication. 66. The metabolism of halogenobenzenes. 1:2:3-, 1:2:4- and 1:3:5-trichlorobenzenes

W. R. Jondorf, D. V. Parke, R. T. Williams

Biochem J (1955) 61 (3): 512–521.

https://doi.org/10.1042/bj0610512

Published: 01 November 1955

View article titled, Studies in detoxication. 66. The metabolism of halogenobenzenes. 1:2:3-, 1:2:4- and 1:3:5-trichlorobenzenes

Articles

Studies in detoxication. 62. The metabolism of halogenobenzenes. Ortho - and para -dichlorobenzenes

W. M. Azouz, D. V. Parke, R. T. Williams

Biochem J (1955) 59 (3): 410–415.

https://doi.org/10.1042/bj0590410

Published: 01 March 1955

View article titled, Studies in detoxication. 62. The metabolism of halogenobenzenes. Ortho - and para -dichlorobenzenes

Articles

Studies in detoxication. 63. The metabolism of halogenobenzenes. ( a ) Meta -dichlorobenzene. ( b ) Further observations on the metabolism of chlorobenzene

D. V. Parke, R. T. Williams

Biochem J (1955) 59 (3): 415–422.

https://doi.org/10.1042/bj0590415

Published: 01 March 1955

View article titled, Studies in detoxication. 63. The metabolism of halogenobenzenes. ( a ) Meta -dichlorobenzene. ( b ) Further observations on the metabolism of chlorobenzene

Articles

Studies in detoxication. 64. The synthesis of the isomeric dichlorophenylmercapturic acids

D. V. Parke

Biochem J (1955) 59 (3): 422–426.

https://doi.org/10.1042/bj0590422

Published: 01 March 1955

View article titled, Studies in detoxication. 64. The synthesis of the isomeric dichlorophenylmercapturic acids

Articles

Studies in detoxication. 54. The metabolism of benzene. ( a ) The formation of phenylglucuronide and phenylsulphuric acid from [ 14 C]benzene. ( b ) The metabolism of [ 14 C]phenol

D. V. Parke, R. T. Williams

Biochem J (1953) 55 (2): 337–340.

https://doi.org/10.1042/bj0550337

Published: 01 September 1953

View article titled, Studies in detoxication. 54. The metabolism of benzene. ( a ) The formation of phenylglucuronide and phenylsulphuric acid from [ 14 C]benzene. ( b ) The metabolism of [ 14 C]phenol

Articles

Studies in detoxication. 51. The determination of catechols in urine, and the formation of catechols in rabbits receiving halogenobenzenes and other compounds. Dihydroxylation in vivo

W. M. Azouz, D. V. Parke, R. T. Williams

Biochem J (1953) 55 (1): 146–151.

https://doi.org/10.1042/bj0550146

Published: 01 August 1953

View article titled, Studies in detoxication. 51. The determination of catechols in urine, and the formation of catechols in rabbits receiving halogenobenzenes and other compounds. Dihydroxylation in vivo

Articles

Studies in detoxication. 49. The metabolism of benzene containing [ 14 C 1 ]benzene

D. V. Parke, R. T. Williams

Biochem J (1953) 54 (2): 231–238.

https://doi.org/10.1042/bj0540231

Published: 01 May 1953

View article titled, Studies in detoxication. 49. The metabolism of benzene containing [ 14 C 1 ]benzene

Articles

Studies in detoxication. 44. The metabolism of benzene. The muconic acid excreted by rabbits receiving benzene. Determination of the isomeric muconic acids

D. V. Parke, R. T. Williams

Biochem J (1952) 51 (3): 339–348.

https://doi.org/10.1042/bj0510339

Published: 01 June 1952

View article titled, Studies in detoxication. 44. The metabolism of benzene. The muconic acid excreted by rabbits receiving benzene. Determination of the isomeric muconic acids

Articles

Studies in detoxication. 42. Fluorobenzene. Spectrophotometric determination of the elimination of unchanged halogenobenzenes by rabbits. A comparison of the oxidation in vivo of fluorobenzene and of benzene

W. M. Azouz, D. V. Parke, R. T. Williams

Biochem J (1952) 50 (5): 702–706.

https://doi.org/10.1042/bj0500702

Published: 01 March 1952

View article titled, Studies in detoxication. 42. Fluorobenzene. Spectrophotometric determination of the elimination of unchanged halogenobenzenes by rabbits. A comparison of the oxidation in vivo of fluorobenzene and of benzene

Articles

Studies in detoxication. 38. The metabolism of benzene. ( a ) The determination of phenylmercapturic acid in urine. ( b ) Mercapturic acid excretion by rabbits receiving benzene

D. V. Parke, R. T. Williams

Biochem J (1951) 48 (5): 624–629.

https://doi.org/10.1042/bj0480624

Published: 01 May 1951

View article titled, Studies in detoxication. 38. The metabolism of benzene. ( a ) The determination of phenylmercapturic acid in urine. ( b ) Mercapturic acid excretion by rabbits receiving benzene

Articles

Studies in detoxication. 37. Metabolism of benzene. Examination of the glucuronide fraction of rabbit urine after administration of benzene. Isolation of phenylglucuronide

D. V. Parke, R. T. Williams

Biochem J (1951) 48 (5): 621–624.

https://doi.org/10.1042/bj0480621

Published: 01 May 1951

View article titled, Studies in detoxication. 37. Metabolism of benzene. Examination of the glucuronide fraction of rabbit urine after administration of benzene. Isolation of phenylglucuronide

Articles

Studies in detoxication. 30. The metabolism of benzene. ( a ) The determination of benzene. ( b ) The elimination of unchanged benzene by rabbits

D. V. Parke, R. T. Williams

Biochem J (1950) 46 (2): 236–243.

https://doi.org/10.1042/bj0460236

Published: 01 February 1950

View article titled, Studies in detoxication. 30. The metabolism of benzene. ( a ) The determination of benzene. ( b ) The elimination of unchanged benzene by rabbits

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