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Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators

Manuel Johanns, Cyril Corbet, Roxane Jacobs, Melissa Drappier, Guido T. Bommer, Gaëtan Herinckx, Didier Vertommen, Nicolas Tajeddine, David Young, Joris Messens, Olivier Feron, Gregory R. Steinberg, Louis Hue, Mark H. Rider

Biochem J (2022) 479 (12): 1317–1336.

https://doi.org/10.1042/BCJ20220170

Published: 22 June 2022

View articletitled, Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators

Includes: Supplementary data

Articles

Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Nusrat Hussain, Sheng-Ju Chuang, Manuel Johanns, Didier Vertommen, Gregory R. Steinberg, Bruce E. Kemp, Mark H. Rider

Biochem J (2020) 477 (23): 4599–4601.

https://doi.org/10.1042/BCJ-2019-0788_COR

Published: 08 December 2020

View articletitled, Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Articles

Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Nusrat Hussain, Sheng-Ju Chuang, Manuel Johanns, Didier Vertommen, Gregory R. Steinberg, Bruce E. Kemp, Mark H. Rider

Biochem J (2020) 477 (8): 1373–1389.

https://doi.org/10.1042/BCJ20190788

Published: 23 April 2020

View articletitled, Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Includes: Supplementary data

Articles

Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia

Aphrodite T. Choumessi, Manuel Johanns, Claire Beaufay, Marie-France Herent, Vincent Stroobant, Didier Vertommen, Cyril Corbet, Roxane Jacobs, Gaëtan Herinckx, Gregory R. Steinberg, Olivier Feron, Joëlle Quetin-Leclercq, Mark H. Rider

Biochem J (2019) 476 (24): 3687–3704.

https://doi.org/10.1042/BCJ20190326

Published: 17 December 2019

View articletitled, Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia

Includes: Supplementary data

Articles

Pyridoxamine-phosphate oxidases and pyridoxamine-phosphate oxidase-related proteins catalyze the oxidation of 6-NAD(P)H to NAD(P) +

Alexandre Y. Marbaix, Georges Chehade, Gaëtane Noël, Pierre Morsomme, Didier Vertommen, Guido T. Bommer, Emile Van Schaftingen

Biochem J (2019) 476 (20): 3033–3052.

https://doi.org/10.1042/BCJ20190602

Published: 28 October 2019

View articletitled, Pyridoxamine-phosphate oxidases and pyridoxamine-phosphate oxidase-related proteins catalyze the oxidation of 6-NAD(P)H to NAD(P) +

Includes: Supplementary data

Articles

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

Yu-Chiang Lai, Samanta Kviklyte, Didier Vertommen, Louise Lantier, Marc Foretz, Benoît Viollet, Stefan Hallén, Mark H. Rider

Biochem J (2014) 460 (3): 363–375.

https://doi.org/10.1042/BJ20131673

Published: 29 May 2014

View articletitled, A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

Includes: Supplementary data

Articles

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

Yang Liu, Yu-Chiang Lai, Elaine V. Hill, Donatienne Tyteca, Sarah Carpentier, Ada Ingvaldsen, Didier Vertommen, Louise Lantier, Marc Foretz, Franck Dequiedt, Pierre J. Courtoy, Christophe Erneux, Benoît Viollet, Peter R. Shepherd, Jeremy M. Tavaré, Jørgen Jensen, Mark H. Rider

Biochem J (2013) 455 (2): 195–206.

https://doi.org/10.1042/BJ20130644

Published: 27 September 2013

View articletitled, Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

Includes: Supplementary data

Articles

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

Laura Novellasdemunt, Laurent Bultot, Anna Manzano, Francesc Ventura, Jose Luis Rosa, Didier Vertommen, Mark H. Rider, Àurea Navarro-Sabate, Ramon Bartrons

Biochem J (2013) 452 (3): 531–543.

https://doi.org/10.1042/BJ20121886

Published: 31 May 2013

View articletitled, PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

Includes: Supplementary data

Articles

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Laurent Bultot, Bruno Guigas, Alexander Von Wilamowitz-Moellendorff, Liliane Maisin, Didier Vertommen, Nusrat Hussain, Monique Beullens, Joan J. Guinovart, Marc Foretz, Benoît Viollet, Kei Sakamoto, Louis Hue, Mark H. Rider

Biochem J (2012) 443 (1): 193–203.

https://doi.org/10.1042/BJ20112026

Published: 14 March 2012

View articletitled, AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Includes: Supplementary data

Articles

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

Sébastien Pyr Dit Ruys, Xuemin Wang, Ewan M. Smith, Gaëtan Herinckx, Nusrat Hussain, Mark H. Rider, Didier Vertommen, Christopher G. Proud

Biochem J (2012) 442 (3): 681–692.

https://doi.org/10.1042/BJ20111530

Published: 24 February 2012

View articletitled, Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

Includes: Supplementary data

Articles

HDHD1 , which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5′-phosphatase

Alice Preumont, Rim Rzem, Didier Vertommen, Emile Van Schaftingen

Biochem J (2010) 431 (2): 237–244.

https://doi.org/10.1042/BJ20100174

Published: 28 September 2010

View articletitled, HDHD1 , which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5′-phosphatase

Articles

Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3)

Véronique Mouton, Louise Toussaint, Didier Vertommen, Marie-Agnès Gueuning, Liliane Maisin, Xavier Havaux, Cossette Sanchez-Canedo, Luc Bertrand, Franck Dequiedt, Brian A. Hemmings, Louis Hue, Mark H. Rider

Biochem J (2010) 431 (2): 267–275.

https://doi.org/10.1042/BJ20101089

Published: 28 September 2010

View articletitled, Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3)

Includes: Supplementary data

Articles

Identification of protein-ribulosamine-5-phosphatase as human low-molecular-mass protein tyrosine phosphatase-A

Juliette Fortpied, Rita Gemayel, Didier Vertommen, Emile Van Schaftingen

Biochem J (2007) 406 (1): 139–145.

https://doi.org/10.1042/BJ20061485

Published: 26 July 2007

View articletitled, Identification of protein-ribulosamine-5-phosphatase as human low-molecular-mass protein tyrosine phosphatase-A

Articles

Increased protein glycation in fructosamine 3-kinase-deficient mice

Maria VEIGA da-Cunha, Patrick Jacquemin, Ghislain Delpierre, Catherine Godfraind, Ivan Théate, Didier Vertommen, Frédéric Clotman, Frédéric Lemaigre, Olivier Devuyst, Emile Van Schaftingen

Biochem J (2006) 399 (2): 257–264.

https://doi.org/10.1042/BJ20060684

Published: 27 September 2006

View articletitled, Increased protein glycation in fructosamine 3-kinase-deficient mice

Articles

Fructosamine 3-kinase-related protein and deglycation in human erythrocytes

François COLLARD, Elsa WIAME, Niki BERGANS, Juliette FORTPIED, Didier VERTOMMEN, Florent VANSTAPEL, Ghislain DELPIERRE, Emile VAN SCHAFTINGEN

Biochem J (2004) 382 (1): 137–143.

https://doi.org/10.1042/BJ20040307

Published: 10 August 2004

View articletitled, Fructosamine 3-kinase-related protein and deglycation in human erythrocytes

Articles

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

Mark H. RIDER, Luc BERTRAND, Didier VERTOMMEN, Paul A. MICHELS, Guy G. ROUSSEAU, Louis HUE

Biochem J (2004) 381 (3): 561–579.

https://doi.org/10.1042/BJ20040752

Published: 27 July 2004

View articletitled, 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

Articles

Identification of a dehydrogenase acting on D-2-hydroxyglutarate

Younes ACHOURI, Gaëtane NOËL, Didier VERTOMMEN, Mark H. RIDER, Maria VEIGA-DA-CUNHA, Emile van SCHAFTINGEN

Biochem J (2004) 381 (1): 35–42.

https://doi.org/10.1042/BJ20031933

Published: 22 June 2004

View articletitled, Identification of a dehydrogenase acting on D-2-hydroxyglutarate

Articles

Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase on adenylate kinase

Luc BERTRAND, Didier VERTOMMEN, Eric DEPIEREUX, Louis HUE, Mark H. RIDER, Ernest FEYTMANS

Biochem J (1997) 321 (3): 615–621.

https://doi.org/10.1042/bj3210615

Published: 01 February 1997

View articletitled, Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase on adenylate kinase

Articles

Site-directed mutagenesis of Lys-174, Asp-179 and Asp-191 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

Luc BERTRAND, Johan DEPREZ, Didier VERTOMMEN, Attilio DI PIETRO, Louis HUE, Mark H. RIDER

Biochem J (1997) 321 (3): 623–627.

https://doi.org/10.1042/bj3210623

Published: 01 February 1997

View articletitled, Site-directed mutagenesis of Lys-174, Asp-179 and Asp-191 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

Articles

Mutagenesis of charged residues in a conserved sequence in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

Luc BERTRAND, Didier VERTOMMEN, Ernest FEYTMANS, Attilio Di PIETRO, Mark H. RIDER, Louis HUE

Biochem J (1997) 321 (3): 609–614.

https://doi.org/10.1042/bj3210609

Published: 01 February 1997

View articletitled, Mutagenesis of charged residues in a conserved sequence in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

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Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators

Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue

Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia

Pyridoxamine-phosphate oxidases and pyridoxamine-phosphate oxidase-related proteins catalyze the oxidation of 6-NAD(P)H to NAD(P) +

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

HDHD1 , which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5′-phosphatase

Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3)

Identification of protein-ribulosamine-5-phosphatase as human low-molecular-mass protein tyrosine phosphatase-A

Increased protein glycation in fructosamine 3-kinase-deficient mice

Fructosamine 3-kinase-related protein and deglycation in human erythrocytes

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

Identification of a dehydrogenase acting on D-2-hydroxyglutarate

Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase on adenylate kinase

Site-directed mutagenesis of Lys-174, Asp-179 and Asp-191 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

Mutagenesis of charged residues in a conserved sequence in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

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