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Ernst R. WERNER
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Articles

Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase

Open Access
Katrin Watschinger, Julian E. Fuchs, Vladimir Yarov-Yarovoy, Markus A. Keller, Georg Golderer, Albin Hermetter, Gabriele Werner-Felmayer, Nicolas Hulo, Ernst R. Werner
Journal: Biochemical Journal
Biochem J (2012) 443 (1): 279–286.
https://doi.org/10.1042/BJ20111509
Published: 14 March 2012
View articletitled, Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase
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Includes: Supplementary data
Articles

Tetrahydrobiopterin: biochemistry and pathophysiology

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Ernst R. Werner, Nenad Blau, Beat Thöny
Journal: Biochemical Journal
Biochem J (2011) 438 (3): 397–414.
https://doi.org/10.1042/BJ20110293
Published: 26 August 2011
View articletitled, Tetrahydrobiopterin: biochemistry and pathophysiology
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Articles

Physarum nitric oxide synthases: genomic structures and enzymology of recombinant proteins

Open Access
Simon Messner, Stephan Leitner, Christian Bommassar, Georg Golderer, Peter Gröbner, Ernst R. Werner, Gabriele Werner-Felmayer
Journal: Biochemical Journal
Biochem J (2009) 418 (3): 691–700.
https://doi.org/10.1042/BJ20080192
Published: 25 February 2009
View articletitled, Physarum nitric oxide synthases: genomic structures and enzymology of recombinant proteins
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Articles

Interaction of human GTP cyclohydrolase I with its splice variants

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Maya J. Pandya, Georg Golderer, Ernst R. Werner, Gabriele Werner-Felmayer
Journal: Biochemical Journal
Biochem J (2006) 400 (1): 75–80.
https://doi.org/10.1042/BJ20060765
Published: 27 October 2006
View articletitled, Interaction of human GTP cyclohydrolase I with its splice variants
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Articles

Low tetrahydrobiopterin biosynthetic capacity of human monocytes is caused by exon skipping in 6-pyruvoyl tetrahydropterin synthase

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Karin L. LEITNER, Martina MEYER, Walter LEIMBACHER, Anja PETERBAUER, Susanne HOFER, Christine HEUFLER, Angelika MÜLLER, Regine HELLER, Ernst R. WERNER, Beat THÖNY, Gabriele WERNER-FELMAYER
Journal: Biochemical Journal
Biochem J (2003) 373 (3): 681–688.
https://doi.org/10.1042/bj20030269
Published: 01 August 2003
View articletitled, Low tetrahydrobiopterin biosynthetic capacity of human monocytes is caused by exon skipping in 6-pyruvoyl tetrahydropterin synthase
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Articles

GTP cyclohydrolase I mRNA: novel splice variants in the slime mould Physarum polycephalum and in human monocytes (THP-1) indicate conservation of mRNA processing

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Georg GOLDERER, Ernst R. WERNER, Christine HEUFLER, Wolfgang STROHMAIER, Peter GRÖBNER, Gabriele WERNER-FELMAYER
Journal: Biochemical Journal
Biochem J (2001) 355 (2): 499–507.
https://doi.org/10.1042/bj3550499
Published: 06 April 2001
View articletitled, GTP cyclohydrolase I mRNA: novel splice variants in the slime mould Physarum polycephalum and in human monocytes (THP-1) indicate conservation of mRNA processing
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Articles

Contrasting effects of N5-substituted tetrahydrobiopterin derivatives on phenylalanine hydroxylase, dihydropteridine reductase and nitric oxide synthase

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Ernst R. WERNER, Hans-Jörg HABISCH, Antonius C. F. GORREN, Kurt SCHMIDT, Laura CANEVARI, Gabriele WERNER-FELMAYER, Bernd MAYER
Journal: Biochemical Journal
Biochem J (2000) 348 (3): 579–583.
https://doi.org/10.1042/bj3480579
Published: 07 June 2000
View articletitled, Contrasting effects of N5-substituted tetrahydrobiopterin derivatives on phenylalanine hydroxylase, dihydropteridine reductase and nitric oxide synthase
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Articles

Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin

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Antonius C. F. GORREN, Astrid SCHRAMMEL, Christoph RIETHMÜLLER, Kurt SCHMIDT, Doris KOESLING, Ernst R. WERNER, Bernd MAYER
Journal: Biochemical Journal
Biochem J (2000) 347 (2): 475–484.
https://doi.org/10.1042/bj3470475
Published: 10 April 2000
View articletitled, Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin
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Articles

Haem insertion, dimerization and reactivation of haem-free rat neuronal nitric oxide synthase

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Benjamin HEMMENS, Antonius C. F. GORREN, Kurt SCHMIDT, Ernst R. WERNER, Bernd MAYER
Journal: Biochemical Journal
Biochem J (1998) 332 (2): 337–342.
https://doi.org/10.1042/bj3320337
Published: 01 June 1998
View articletitled, Haem insertion, dimerization and reactivation of haem-free rat neuronal nitric oxide synthase
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Articles

Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization

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Barbara M. LIST, Burkhard KLÖSCH, Christof VÖLKER, Antonius C. F. GORREN, William C. SESSA, Ernst R. WERNER, Walter R. KUKOVETZ, Kurt SCHMIDT, Bernd MAYER
Journal: Biochemical Journal
Biochem J (1997) 323 (1): 159–165.
https://doi.org/10.1042/bj3230159
Published: 01 April 1997
View articletitled, Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization
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Articles

Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase

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Ernst R. WERNER, Eva PITTERS, Kurt SCHMIDT, Helmut WACHTER, Gabriele WERNER-FELMAYER, Bernd MAYER
Journal: Biochemical Journal
Biochem J (1996) 320 (1): 193–196.
https://doi.org/10.1042/bj3200193
Published: 15 November 1996
View articletitled, Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase
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Articles

Interleukin 1 β and cAMP trigger the expression of GTP cyclohydrolase I in rat renal mesangial cells

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Christoph PLÜSS, Ernst R. WERNER, Nenad BLAU, Helmut WACHTER, Josef PFEILSCHIFTER
Journal: Biochemical Journal
Biochem J (1996) 318 (2): 665–671.
https://doi.org/10.1042/bj3180665
Published: 01 September 1996
View articletitled, Interleukin 1 β and cAMP trigger the expression of GTP cyclohydrolase I in rat renal mesangial cells
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Articles

Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding

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Barbara M. LIST, Peter KLATT, Ernst R. WERNER, Kurt SCHMIDT, Bernd MAYER
Journal: Biochemical Journal
Biochem J (1996) 315 (1): 57–63.
https://doi.org/10.1042/bj3150057
Published: 01 April 1996
View articletitled, Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding
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