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Harinder S. Hundal
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Articles

The pro-drug C13 activates AMPK by two distinct mechanisms

Jordana B. Freemantle, Dinesh Shah, Dylan M. Lynch, Alessio Ciulli, Harinder S. Hundal, D. Grahame Hardie
Journal: Biochemical Journal
Biochem J (2024) 481 (18): 1203–1219.
https://doi.org/10.1042/BCJ20240425
Published: 12 September 2024
View article titled, The pro-drug C13 activates AMPK by two distinct mechanisms
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Includes: Supplementary data
Articles

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

Clare Stretton, Thorsten M. Hoffmann, Michael J. Munson, Alan Prescott, Peter M. Taylor, Ian G. Ganley, Harinder S. Hundal
Journal: Biochemical Journal
Biochem J (2015) 470 (2): 207–221.
https://doi.org/10.1042/BJ20150404
Published: 20 August 2015
View article titled, GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling
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Includes: Supplementary data
Articles

Counter-modulation of fatty acid-induced pro-inflammatory nuclear factor κB signalling in rat skeletal muscle cells by AMP-activated protein kinase

Charlotte J. Green, Katherine Macrae, Sarah Fogarty, D. Grahame Hardie, Kei Sakamoto, Harinder S. Hundal
Journal: Biochemical Journal
Biochem J (2011) 435 (2): 463–474.
https://doi.org/10.1042/BJ20101517
Published: 29 March 2011
View article titled, Counter-modulation of fatty acid-induced pro-inflammatory nuclear factor κB signalling in rat skeletal muscle cells by AMP-activated protein kinase
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Includes: Supplementary data
Articles

Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells

Maria L. Watson, Matthew Coghlan, Harinder S. Hundal
Journal: Biochemical Journal
Biochem J (2009) 417 (3): 791–801.
https://doi.org/10.1042/BJ20081149
Published: 16 January 2009
View article titled, Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells
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Includes: Supplementary data
Articles

Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

Eric Hajduch, Sophie Turban, Xavier Le Liepvre, Soazig Le Lay, Christopher Lipina, Nikolaos Dimopoulos, Isabelle Dugail, Harinder S. Hundal
Journal: Biochemical Journal
Biochem J (2008) 410 (2): 369–379.
https://doi.org/10.1042/BJ20070936
Published: 12 February 2008
View article titled, Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide
Open the PDF for Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide in another window
Includes: Supplementary data
Articles

Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells

Nikolaos Dimopoulos, Maria Watson, Kei Sakamoto, Harinder S. Hundal
Journal: Biochemical Journal
Biochem J (2006) 399 (3): 473–481.
https://doi.org/10.1042/BJ20060244
Published: 13 October 2006
View article titled, Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells
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Articles

Evidence for allosteric regulation of pH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity involving a conserved histidine residue

Fiona E. Baird, Jorge J. Pinilla-Tenas, William L. J. Ogilvie, Vadival Ganapathy, Harinder S. Hundal, Peter M. Taylor
Journal: Biochemical Journal
Biochem J (2006) 397 (2): 369–375.
https://doi.org/10.1042/BJ20060026
Published: 28 June 2006
View article titled, Evidence for allosteric regulation of pH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity involving a conserved histidine residue
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Articles

Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

Darren J. POWELL, Sophie TURBAN, Alexander GRAY, Eric HAJDUCH, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (2004) 382 (2): 619–629.
https://doi.org/10.1042/BJ20040139
Published: 24 August 2004
View article titled, Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
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Articles

Amino acid transporters: roles in amino acid sensing and signalling in animal cells

Russell HYDE, Peter M. TAYLOR, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (2003) 373 (1): 1–18.
https://doi.org/10.1042/bj20030405
Published: 01 July 2003
View article titled, Amino acid transporters: roles in amino acid sensing and signalling in animal cells
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Articles

Subcellular localization and adaptive up-regulation of the System A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes

Russell HYDE, Graham R. CHRISTIE, Gary J. LITHERLAND, Eric HAJDUCH, Peter M. TAYLOR, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (2001) 355 (3): 563–568.
https://doi.org/10.1042/bj3550563
Published: 24 April 2001
View article titled, Subcellular localization and adaptive up-regulation of the System A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes
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Articles

A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B

Karine PEYROLLIER, Eric HAJDUCH, Alexander GRAY, Gary J. LITHERLAND, Alan R. PRESCOTT, Nick R. LESLIE, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (2000) 352 (3): 617–622.
https://doi.org/10.1042/bj3520617
Published: 08 December 2000
View article titled, A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B
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Articles

l-Leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the l-leucine-induced up-regulation of System A amino acid transport

Karine PEYROLLIER, Eric HAJDUCH, Anne S. BLAIR, Russell HYDE, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (2000) 350 (2): 361–368.
https://doi.org/10.1042/bj3500361
Published: 23 August 2000
View article titled, l-Leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the l-leucine-induced up-regulation of System A amino acid transport
Open the PDF for l-Leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the l-leucine-induced up-regulation of System A amino acid transport in another window
Articles

Biochemical and functional characterization of the GLUT5 fructose transporter in rat skeletal muscle

Froogh DARAKHSHAN, Eric HAJDUCH, Søren KRISTIANSEN, Erik A. RICHTER, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (1998) 336 (2): 361–366.
https://doi.org/10.1042/bj3360361
Published: 01 December 1998
View article titled, Biochemical and functional characterization of the GLUT5 fructose transporter in rat skeletal muscle
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Articles

Identification and characterization of two distinct intracellular GLUT4 pools in rat skeletal muscle: evidence for an endosomal and an insulin-sensitive GLUT4 compartment

J. Carlos ALEDO, Louis LAVOIE, Allen VOLCHUK, Susanna R. KELLER, Amira KLIP, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (1997) 325 (3): 727–732.
https://doi.org/10.1042/bj3250727
Published: 01 August 1997
View article titled, Identification and characterization of two distinct intracellular GLUT4 pools in rat skeletal muscle: evidence for an endosomal and an insulin-sensitive GLUT4 compartment
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Articles

Proteolytic cleavage of cellubrevin and vesicle-associated membrane protein (VAMP) by tetanus toxin does not impair insulin-stimulated glucose transport or GLUT4 translocation in rat adipocytes

Eric HAJDUCH, J. Carlos ALEDO, Colin WATTS, Harinder S. HUNDAL
Journal: Biochemical Journal
Biochem J (1997) 321 (1): 233–238.
https://doi.org/10.1042/bj3210233
Published: 01 January 1997
View article titled, Proteolytic cleavage of cellubrevin and vesicle-associated membrane protein (VAMP) by tetanus toxin does not impair insulin-stimulated glucose transport or GLUT4 translocation in rat adipocytes
Open the PDF for Proteolytic cleavage of cellubrevin and vesicle-associated membrane protein (VAMP) by tetanus toxin does not impair insulin-stimulated glucose transport or GLUT4 translocation in rat adipocytes in another window