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Jeffrey L. Brodsky
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Articles

Lhs1 dependent ERAD is determined by transmembrane domain context

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Maria Sukhoplyasova, Abigail M. Keith, Emma M. Perrault, Hannah E. Vorndran, Alexa S. Jordahl, Megan E. Yates, Ashutosh Pastor, Zachary Li, Michael L. Freaney, Riddhi A. Deshpande, David B. Adams, Christopher J. Guerriero, Shujie Shi, Thomas R. Kleyman, Ossama B. Kashlan, Jeffrey L. Brodsky, Teresa M. Buck
Journal: Biochemical Journal
Biochem J (2023) 480 (18): 1459–1473.
https://doi.org/10.1042/BCJ20230075
Published: 21 September 2023
View articletitled, Lhs1 dependent ERAD is determined by transmembrane domain context
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Includes: Supplementary data
Articles

SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain

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Patrick G. Needham, Jennifer L. Goeckeler-Fried, Casey Zhang, Zhihao Sun, Adam R. Wetzel, Carol A. Bertrand, Jeffrey L. Brodsky
Journal: Biochemical Journal
Biochem J (2021) 478 (24): 4203–4220.
https://doi.org/10.1042/BCJ20210644
Published: 23 December 2021
View articletitled, SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain
Open the PDF for SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain in another window
Includes: Supplementary data
Articles

The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation

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G. Michael Preston, Jeffrey L. Brodsky
Journal: Biochemical Journal
Biochem J (2017) 474 (4): 445–469.
https://doi.org/10.1042/BCJ20160582
Published: 03 February 2017
View articletitled, The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation
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Articles

Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein

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Teresa M. Buck, Alexa S. Jordahl, Megan E. Yates, G. Michael Preston, Emily Cook, Thomas R. Kleyman, Jeffrey L. Brodsky
Journal: Biochemical Journal
Biochem J (2017) 474 (3): 357–376.
https://doi.org/10.1042/BCJ20160760
Published: 20 January 2017
View articletitled, Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein
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Includes: Supplementary data
Articles

The Cdc48–Vms1 complex maintains 26S proteasome architecture

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Joseph R. Tran, Jeffrey L. Brodsky
Journal: Biochemical Journal
Biochem J (2014) 458 (3): 459–467.
https://doi.org/10.1042/BJ20131161
Published: 28 February 2014
View articletitled, The Cdc48–Vms1 complex maintains 26S proteasome architecture
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Includes: Supplementary data
Articles

Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence

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Domina Falcone, Matthew P. Henderson, Hendrik Nieuwland, Christine M. Coughlan, Jeffrey L. Brodsky, David W. Andrews
Journal: Biochemical Journal
Biochem J (2011) 436 (2): 291–303.
https://doi.org/10.1042/BJ20101865
Published: 13 May 2011
View articletitled, Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence
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Includes: Supplementary data
Articles

Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities

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Bhargavi Patham, Josh Duffy, Ariel Lane, Richard C. Davis, Peter Wipf, Sheara W. Fewell, Jeffrey L. Brodsky, Kojo Mensa-Wilmot
Journal: Biochemical Journal
Biochem J (2009) 419 (2): 507–517.
https://doi.org/10.1042/BJ20081787
Published: 27 March 2009
View articletitled, Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities
Open the PDF for Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities in another window
Articles

The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation)

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Jeffrey L. Brodsky
Journal: Biochemical Journal
Biochem J (2007) 404 (3): 353–363.
https://doi.org/10.1042/BJ20061890
Published: 29 May 2007
View articletitled, The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation)
Open the PDF for The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation) in another window