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Joachim Grötzinger
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Articles

Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of interleukin-6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3

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Mirja Oldefest, Stefan Düsterhöft, Christine Desel, Sarah Thysen, Christine Fink, Björn Rabe, Rik Lories, Joachim Grötzinger, Inken Lorenzen
Journal: Biochemical Journal
Biochem J (2015) 468 (3): 507–518.
https://doi.org/10.1042/BJ20141231
Published: 15 June 2015
View articletitled, Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of interleukin-6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3
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Includes: Supplementary data
Articles

gp130 activation is regulated by D2–D3 interdomain connectivity

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Antje Schütt, Martin Zacharias, Nico Schneider, Silke Horn, Joachim Grötzinger, Stefan Rose-John, Dirk Schmidt-Arras
Journal: Biochemical Journal
Biochem J (2013) 450 (3): 487–496.
https://doi.org/10.1042/BJ20121660
Published: 28 February 2013
View articletitled, gp130 activation is regulated by D2–D3 interdomain connectivity
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Includes: Supplementary data
Articles

A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells

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Kosuke Yamamoto, Ahmad Trad, Anja Baumgart, Linda Hüske, Inken Lorenzen, Athena Chalaris, Joachim Grötzinger, Tobias Dechow, Jürgen Scheller, Stefan Rose-John
Journal: Biochemical Journal
Biochem J (2012) 445 (1): 135–144.
https://doi.org/10.1042/BJ20120433
Published: 15 June 2012
View articletitled, A novel bispecific single-chain antibody for ADAM17 and CD3 induces T-cell-mediated lysis of prostate cancer cells
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Includes: Supplementary data
Articles

An exceptional salt-tolerant antimicrobial peptide derived from a novel gene family of haemocytes of the marine invertebrate Ciona intestinalis

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Henning Fedders, Matthias Michalek, Joachim Grötzinger, Matthias Leippe
Journal: Biochemical Journal
Biochem J (2008) 416 (1): 65–75.
https://doi.org/10.1042/BJ20080398
Published: 28 October 2008
View articletitled, An exceptional salt-tolerant antimicrobial peptide derived from a novel gene family of haemocytes of the marine invertebrate Ciona intestinalis
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Articles

Structure and mode of action of the antimicrobial peptide arenicin

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Jörg Andrä, Igor Jakovkin, Joachim Grötzinger, Oliver Hecht, Anna D. Krasnosdembskaya, Torsten Goldmann, Thomas Gutsmann, Matthias Leippe
Journal: Biochemical Journal
Biochem J (2008) 410 (1): 113–122.
https://doi.org/10.1042/BJ20071051
Published: 29 January 2008
View articletitled, Structure and mode of action of the antimicrobial peptide arenicin
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Articles

A novel horse α-defensin: gene transcription, recombinant expression and characterization of the structure and function

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Oliver Bruhn, Petra Regenhard, Matthias Michalek, Sven Paul, Christoph Gelhaus, Sascha Jung, Georg Thaller, Rainer Podschun, Matthias Leippe, Joachim Grötzinger, Ernst Kalm
Journal: Biochemical Journal
Biochem J (2007) 407 (2): 267–276.
https://doi.org/10.1042/BJ20070747
Published: 25 September 2007
View articletitled, A novel horse α-defensin: gene transcription, recombinant expression and characterization of the structure and function
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Articles

Functional expression of a biologically active fragment of soluble gp130 as an ELP-fusion protein in transgenic plants: purification via inverse transition cycling

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Meng Lin, Stefan Rose-John, Joachim Grötzinger, Udo Conrad, Jürgen Scheller
Journal: Biochemical Journal
Biochem J (2006) 398 (3): 577–583.
https://doi.org/10.1042/BJ20060544
Published: 29 August 2006
View articletitled, Functional expression of a biologically active fragment of soluble gp130 as an ELP-fusion protein in transgenic plants: purification via inverse transition cycling
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Includes: Supplementary data
Articles

Characterization of a potent human interleukin-11 agonist

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Dimitri HARMEGNIES, Xiao-Ming WANG, Paul VANDENBUSSCHE, Arnaud LEON, Patricia VUSIO, Joachim GRÖTZINGER, Yannick JACQUES, Erik GOORMAGHTIGH, Bart DEVREESE, Jean CONTENT
Journal: Biochemical Journal
Biochem J (2003) 375 (1): 23–32.
https://doi.org/10.1042/bj20030459
Published: 01 October 2003
View articletitled, Characterization of a potent human interleukin-11 agonist
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Articles

Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A

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Sunke HIMPEL, Pascal PANZER, Klaus EIRMBTER, Hanna CZAJKOWSKA, Muhammed SAYED, Len C. PACKMAN, Tom BLUNDELL, Heiner KENTRUP, Joachim GRÖTZINGER, Hans-G. JOOST, Walter BECKER
Journal: Biochemical Journal
Biochem J (2001) 359 (3): 497–505.
https://doi.org/10.1042/bj3590497
Published: 25 October 2001
View articletitled, Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A
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Articles

Signal transducer gp130: biochemical characterization of the three membrane-proximal extracellular domains and evaluation of their oligomerization potential

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Stefan PFLANZ, Thomas KERNEBECK, Bernd GIESE, Andreas HERRMANN, Michael PACHTA-NICK, Jürgen STAHL, Axel WOLLMER, Peter C. HEINRICH, Gerhard MÜLLER-NEWEN, Joachim GRÖTZINGER
Journal: Biochemical Journal
Biochem J (2001) 356 (2): 605–612.
https://doi.org/10.1042/bj3560605
Published: 24 May 2001
View articletitled, Signal transducer gp130: biochemical characterization of the three membrane-proximal extracellular domains and evaluation of their oligomerization potential
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Articles

Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins

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Katja ALTHOFF, Jürgen MÜLLBERG, Dorthe AASLAND, Nicole VOLTZ, Karl-Josef KALLEN, Joachim GRÖTZINGER, Stefan ROSE-JOHN
Journal: Biochemical Journal
Biochem J (2001) 353 (3): 663–672.
https://doi.org/10.1042/bj3530663
Published: 25 January 2001
View articletitled, Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins
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