1-3 of 3
John E. Burke
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding

Grace Q. Gong, Glenn R. Masson, Woo-Jeong Lee, James M. J. Dickson, Jackie D. Kendall, Manoj K. Rathinaswamy, Christina M. Buchanan, Martin Middleditch, Brady M. Owen, Julie A. Spicer, Gordon W. Rewcastle, William A. Denny, John E. Burke, Peter R. Shepherd, Roger L. Williams, Jack U. Flanagan
Journal: Biochemical Journal
Biochem J (2024) 481 (23): 1787–1802.
https://doi.org/10.1042/BCJ20240479
Published: 28 November 2024
View articletitled, ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding
Open the PDF for ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding in another window
Includes: Supplementary data
Articles

The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity

Glenn R. Masson, Olga Perisic, John E. Burke, Roger L. Williams
Journal: Biochemical Journal
Biochem J (2016) 473 (2): 135–144.
https://doi.org/10.1042/BJ20150931
Published: 05 January 2016
View articletitled, The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity
Open the PDF for The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity in another window
Includes: Supplementary data
Articles

The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site

Jonathan H. Clarke, Maria-Luisa Giudici, John E. Burke, Roger L. Williams, David J. Maloney, Juan Marugan, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2015) 466 (2): 359–367.
https://doi.org/10.1042/BJ20141333
Published: 20 February 2015
View articletitled, The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site
Open the PDF for The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site in another window
Includes: Supplementary data