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John M. Kelly
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Articles

Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I)

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Shreenal Patel, Syeed Hussain, Richard Harris, Sunita Sardiwal, John M. Kelly, Shane R. Wilkinson, Paul C. Driscoll, Snezana Djordjevic
Journal: Biochemical Journal
Biochem J (2010) 425 (3): 513–522.
https://doi.org/10.1042/BJ20091167
Published: 15 January 2010
View articletitled, Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I)
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Includes: Supplementary data
Articles

Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite

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Lucía Piacenza, Gonzalo Peluffo, María Noel Alvarez, John M. Kelly, Shane R. Wilkinson, Rafael Radi
Journal: Biochemical Journal
Biochem J (2008) 410 (2): 359–368.
https://doi.org/10.1042/BJ20071138
Published: 12 February 2008
View articletitled, Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite
Open the PDF for Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite in another window
Includes: Supplementary data
Articles

Validation of spermidine synthase as a drug target in African trypanosomes

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Martin C. Taylor, Harparkash Kaur, Bernard Blessington, John M. Kelly, Shane R. Wilkinson
Journal: Biochemical Journal
Biochem J (2008) 409 (2): 563–569.
https://doi.org/10.1042/BJ20071185
Published: 21 December 2007
View articletitled, Validation of spermidine synthase as a drug target in African trypanosomes
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Articles

The terminal step in vitamin C biosynthesis in Trypanosoma cruzi is mediated by a FMN-dependent galactonolactone oxidase

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Flora J. Logan, Martin C. Taylor, Shane R. Wilkinson, Harparkash Kaur, John M. Kelly
Journal: Biochemical Journal
Biochem J (2007) 407 (3): 419–426.
https://doi.org/10.1042/BJ20070766
Published: 12 October 2007
View articletitled, The terminal step in vitamin C biosynthesis in Trypanosoma cruzi is mediated by a FMN-dependent galactonolactone oxidase
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Includes: Supplementary data
Articles

Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi : cytoprotective action of mitochondrial iron superoxide dismutase overexpression

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Lucía Piacenza, Florencia Irigoín, María Noel Alvarez, Gonzalo Peluffo, Martin C. Taylor, John M. Kelly, Shane R. Wilkinson, Rafael Radi
Journal: Biochemical Journal
Biochem J (2007) 403 (2): 323–334.
https://doi.org/10.1042/BJ20061281
Published: 26 March 2007
View articletitled, Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi : cytoprotective action of mitochondrial iron superoxide dismutase overexpression
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Includes: Supplementary data
Articles

TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum

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Shane R. WILKINSON, Martin C. TAYLOR, Said TOUITHA, Isabel L. MAURICIO, David J. MEYER, John M. KELLY
Journal: Biochemical Journal
Biochem J (2002) 364 (3): 787–794.
https://doi.org/10.1042/bj20020038
Published: 15 June 2002
View articletitled, TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum
Open the PDF for TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum in another window
Articles

Biochemical characterization of a trypanosome enzyme with glutathione-dependent peroxidase activity

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Shane R. WILKINSON, David J. MEYER, John M. KELLY
Journal: Biochemical Journal
Biochem J (2000) 352 (3): 755–761.
https://doi.org/10.1042/bj3520755
Published: 08 December 2000
View articletitled, Biochemical characterization of a trypanosome enzyme with glutathione-dependent peroxidase activity
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