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John W. Scott
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Articles

Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator

Open Access
Ashley J. Ovens, Yi Sing Gee, Naomi X.Y. Ling, Dingyi Yu, Justin P. Hardee, Jin D. Chung, Kevin R.W. Ngoei, Nicholas J. Waters, Nolan J. Hoffman, John W. Scott, Kim Loh, Katrin Spengler, Regine Heller, Michael W. Parker, Gordon S. Lynch, Fei Huang, Sandra Galic, Bruce E. Kemp, Jonathan B. Baell, Jonathan S. Oakhill, Christopher G. Langendorf
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1181–1204.
https://doi.org/10.1042/BCJ20220067
Published: 08 June 2022
View articletitled, Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator
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Includes: Supplementary data
Articles

Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

Open Access
Danial Ahwazi, Katyayanee Neopane, Greg R. Markby, Franziska Kopietz, Ashley J. Ovens, Morten Dall, Anna S. Hassing, Pamina Gräsle, Yazeed Alshuweishi, Jonas T. Treebak, Ian P. Salt, Olga Göransson, Elton Zeqiraj, John W. Scott, Kei Sakamoto
Journal: Biochemical Journal
Biochem J (2021) 478 (15): 2977–2997.
https://doi.org/10.1042/BCJ20210284
Published: 10 August 2021
View articletitled, Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965
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Includes: Supplementary data
Articles

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495

Available to Purchase
Katrin Spengler, Darya Zibrova, Angela Woods, Christopher G. Langendorf, John W. Scott, David Carling, Regine Heller
Journal: Biochemical Journal
Biochem J (2020) 477 (17): 3453–3469.
https://doi.org/10.1042/BCJ20200555
Published: 17 September 2020
View articletitled, Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495
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Includes: Supplementary data
Articles

AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis

Open Access
Omar J. Katwan, Fatmah Alghamdi, Tarek A. Almabrouk, Sarah J. Mancini, Simon Kennedy, Jonathan S. Oakhill, John W. Scott, Ian P. Salt
Journal: Biochemical Journal
Biochem J (2019) 476 (12): 1725–1740.
https://doi.org/10.1042/BCJ20180714
Published: 26 June 2019
View articletitled, AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis
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Includes: Supplementary data
Articles

The sweet side of AMPK signaling: regulation of GFAT1

Available to Purchase
John W. Scott, Jonathan S. Oakhill
Journal: Biochemical Journal
Biochem J (2017) 474 (7): 1289–1292.
https://doi.org/10.1042/BCJ20170006
Published: 23 March 2017
View articletitled, The sweet side of AMPK signaling: regulation of GFAT1
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Articles

Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity

Available to Purchase
Rebecca J. Ford, Morgan D. Fullerton, Stephen L. Pinkosky, Emily A. Day, John W. Scott, Jonathan S. Oakhill, Adam L. Bujak, Brennan K. Smith, Justin D. Crane, Regje M. Blümer, Katarina Marcinko, Bruce E. Kemp, Hertzel C. Gerstein, Gregory R. Steinberg
Journal: Biochemical Journal
Biochem J (2015) 468 (1): 125–132.
https://doi.org/10.1042/BJ20150125
Published: 05 May 2015
View articletitled, Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity
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