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Consequences of molecular recognition in the S 1 -S 2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse solvent kinetic isotope effect by introduction of a P 1 -P 2 amide bond into a two-protonic-state reactivity probe

K Brocklehurst, D Kowlessur, G Patel, W Templeton, K Quigley, E W Thomas, C W Wharton, F Willenbrock, R J Szawelski
Journal: Biochemical Journal
Biochem J (1988) 250 (3): 761–772.
https://doi.org/10.1042/bj2500761
Published: 15 March 1988
View article titled, Consequences of molecular recognition in the S 1 -S 2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse solvent kinetic isotope effect by introduction of a P 1 -P 2 amide bond into a two-protonic-state reactivity probe
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