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Articles

AMPK inhibits liver gluconeogenesis: fact or fiction?

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In Collection
Cell signaling in the 21st century
Manuel Johanns, Louis Hue, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2023) 480 (1): 105–125.
https://doi.org/10.1042/BCJ20220582
Published: 13 January 2023
View articletitled, AMPK inhibits liver gluconeogenesis: fact or fiction?
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Articles

Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators

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Manuel Johanns, Cyril Corbet, Roxane Jacobs, Melissa Drappier, Guido T. Bommer, Gaëtan Herinckx, Didier Vertommen, Nicolas Tajeddine, David Young, Joris Messens, Olivier Feron, Gregory R. Steinberg, Louis Hue, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2022) 479 (12): 1317–1336.
https://doi.org/10.1042/BCJ20220170
Published: 22 June 2022
View articletitled, Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators
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Includes: Supplementary data
Articles

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

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Laurent Bultot, Bruno Guigas, Alexander Von Wilamowitz-Moellendorff, Liliane Maisin, Didier Vertommen, Nusrat Hussain, Monique Beullens, Joan J. Guinovart, Marc Foretz, Benoît Viollet, Kei Sakamoto, Louis Hue, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2012) 443 (1): 193–203.
https://doi.org/10.1042/BJ20112026
Published: 14 March 2012
View articletitled, AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase
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Includes: Supplementary data
Articles

Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3)

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Véronique Mouton, Louise Toussaint, Didier Vertommen, Marie-Agnès Gueuning, Liliane Maisin, Xavier Havaux, Cossette Sanchez-Canedo, Luc Bertrand, Franck Dequiedt, Brian A. Hemmings, Louis Hue, Mark H. Rider
Journal: Biochemical Journal
Biochem J (2010) 431 (2): 267–275.
https://doi.org/10.1042/BJ20101089
Published: 28 September 2010
View articletitled, Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3)
Open the PDF for Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3) in another window
Includes: Supplementary data
Articles

AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside

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Bruno Guigas, Nellie Taleux, Marc Foretz, Dominique Detaille, Fabrizio Andreelli, Benoit Viollet, Louis Hue
Journal: Biochemical Journal
Biochem J (2007) 404 (3): 499–507.
https://doi.org/10.1042/BJ20070105
Published: 29 May 2007
View articletitled, AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside
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Includes: Supplementary data
Articles

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

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Mark H. RIDER, Luc BERTRAND, Didier VERTOMMEN, Paul A. MICHELS, Guy G. ROUSSEAU, Louis HUE
Journal: Biochemical Journal
Biochem J (2004) 381 (3): 561–579.
https://doi.org/10.1042/BJ20040752
Published: 27 July 2004
View articletitled, 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis
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Articles

Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase

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Johan DEPREZ, Luc BERTRAND, Dario R. ALESSI, Ulrike KRAUSE, Louis HUE, Mark H. RIDER
Journal: Biochemical Journal
Biochem J (2000) 347 (1): 305–312.
https://doi.org/10.1042/bj3470305
Published: 27 March 2000
View articletitled, Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase
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Articles

Fructose-induced increase in intracellular free Mg 2+ ion concentration in rat hepatocytes: relation with the enzymes of glycogen metabolism

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Vinciane GAUSSIN, Philippe GAILLY, Jean-Marie GILLIS, Louis HUE
Journal: Biochemical Journal
Biochem J (1997) 326 (3): 823–827.
https://doi.org/10.1042/bj3260823
Published: 15 September 1997
View articletitled, Fructose-induced increase in intracellular free Mg 2+ ion concentration in rat hepatocytes: relation with the enzymes of glycogen metabolism
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Articles

Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase on adenylate kinase

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Luc BERTRAND, Didier VERTOMMEN, Eric DEPIEREUX, Louis HUE, Mark H. RIDER, Ernest FEYTMANS
Journal: Biochemical Journal
Biochem J (1997) 321 (3): 615–621.
https://doi.org/10.1042/bj3210615
Published: 01 February 1997
View articletitled, Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase on adenylate kinase
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Articles

Site-directed mutagenesis of Lys-174, Asp-179 and Asp-191 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

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Luc BERTRAND, Johan DEPREZ, Didier VERTOMMEN, Attilio DI PIETRO, Louis HUE, Mark H. RIDER
Journal: Biochemical Journal
Biochem J (1997) 321 (3): 623–627.
https://doi.org/10.1042/bj3210623
Published: 01 February 1997
View articletitled, Site-directed mutagenesis of Lys-174, Asp-179 and Asp-191 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
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Articles

Mutagenesis of charged residues in a conserved sequence in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

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Luc BERTRAND, Didier VERTOMMEN, Ernest FEYTMANS, Attilio Di PIETRO, Mark H. RIDER, Louis HUE
Journal: Biochemical Journal
Biochem J (1997) 321 (3): 609–614.
https://doi.org/10.1042/bj3210609
Published: 01 February 1997
View articletitled, Mutagenesis of charged residues in a conserved sequence in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
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Articles

Activation of hepatic acetyl-CoA carboxylase by glutamate and Mg 2+ is mediated by protein phosphatase-2A

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Vinciane GAUSSIN, Louis HUE, Willy STALMANS, Mathieu BOLLEN
Journal: Biochemical Journal
Biochem J (1996) 316 (1): 217–224.
https://doi.org/10.1042/bj3160217
Published: 15 May 1996
View articletitled, Activation of hepatic acetyl-CoA carboxylase by glutamate and Mg 2+ is mediated by protein phosphatase-2A
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Articles

Control of the fructose 6-phosphate/fructose 1,6-bisphosphate cycle in isolated hepatocytes by glucose and glucagon. Role of a low-molecular-weight stimulator of phosphofructokinase

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Emile Van Schaftingen, Louis Hue, Henri-Géry Hers
Journal: Biochemical Journal
Biochem J (1980) 192 (3): 887–895.
https://doi.org/10.1042/bj1920887
Published: 15 December 1980
View articletitled, Control of the fructose 6-phosphate/fructose 1,6-bisphosphate cycle in isolated hepatocytes by glucose and glucagon. Role of a low-molecular-weight stimulator of phosphofructokinase
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Articles

Control of gluconeogenesis and of enzymes of glycogen metabolism in isolated rat hepatocytes. A parallel study of the effect of phenylephrine and of glucagon

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Louis Hue, Juan Emilio Felíu, Henri-Géry Hers
Journal: Biochemical Journal
Biochem J (1978) 176 (3): 791–797.
https://doi.org/10.1042/bj1760791
Published: 15 December 1978
View articletitled, Control of gluconeogenesis and of enzymes of glycogen metabolism in isolated rat hepatocytes. A parallel study of the effect of phenylephrine and of glucagon
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Articles

Phosphorylation of glucose in isolated rat hepatocytes. Sigmoidal kinetics explained by the activity of glucokinase alone

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Françoise Bontemps, Louis Hue, Henri-Géry Hers
Journal: Biochemical Journal
Biochem J (1978) 174 (2): 603–611.
https://doi.org/10.1042/bj1740603
Published: 15 August 1978
View articletitled, Phosphorylation of glucose in isolated rat hepatocytes. Sigmoidal kinetics explained by the activity of glucokinase alone
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