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Martin J. Humphries
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Articles

Disruption of integrin–fibronectin complexes by allosteric but not ligand-mimetic inhibitors

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A. Paul Mould, Susan E. Craig, Sarah K. Byron, Martin J. Humphries, Thomas A. Jowitt
Journal: Biochemical Journal
Biochem J (2014) 464 (3): 301–313.
https://doi.org/10.1042/BJ20141047
Published: 05 December 2014
View articletitled, Disruption of integrin–fibronectin complexes by allosteric but not ligand-mimetic inhibitors
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Includes: Supplementary data
Articles

Mapping the ligand-binding pocket of integrin α5β1 using a gain-of-function approach

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A. Paul Mould, Ewa J. Koper, Adam Byron, Grit Zahn, Martin J. Humphries
Journal: Biochemical Journal
Biochem J (2009) 424 (2): 179–189.
https://doi.org/10.1042/BJ20090992
Published: 11 November 2009
View articletitled, Mapping the ligand-binding pocket of integrin α5β1 using a gain-of-function approach
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Includes: Supplementary data
Articles

Novel activating and inactivating mutations in the integrin beta1 subunit A domain

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Stephanie J. BARTON, Mark A. TRAVIS, Janet A. ASKARI, Patrick A. BUCKLEY, Susan E. CRAIG, Martin J. HUMPHRIES, A. Paul MOULD
Journal: Biochemical Journal
Biochem J (2004) 380 (2): 401–407.
https://doi.org/10.1042/bj20031973
Published: 01 June 2004
View articletitled, Novel activating and inactivating mutations in the integrin beta1 subunit A domain
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Articles

Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling

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Mark D. BASS, Martin J. HUMPHRIES
Journal: Biochemical Journal
Biochem J (2002) 368 (1): 1–15.
https://doi.org/10.1042/bj20021228
Published: 15 November 2002
View articletitled, Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling
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Articles

Monoclonal antibodies identify residues 199–216 of the integrin α2 vWFA domain as a functionally important region within α2β1

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Danny S. TUCKWELL, Lyndsay SMITH, Michelle KORDA, Janet A. ASKARI, Sentot SANTOSO, Michael J. BARNES, Richard W. FARNDALE, Martin J. HUMPHRIES
Journal: Biochemical Journal
Biochem J (2000) 350 (2): 485–493.
https://doi.org/10.1042/bj3500485
Published: 23 August 2000
View articletitled, Monoclonal antibodies identify residues 199–216 of the integrin α2 vWFA domain as a functionally important region within α2β1
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Articles

Fine mapping of inhibitory anti-α5 monoclonal antibody epitopes that differentially affect integrin–ligand binding

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Louise BURROWS, Katherine CLARK, A. Paul MOULD, Martin J. HUMPHRIES
Journal: Biochemical Journal
Biochem J (1999) 344 (2): 527–533.
https://doi.org/10.1042/bj3440527
Published: 24 November 1999
View articletitled, Fine mapping of inhibitory anti-α5 monoclonal antibody epitopes that differentially affect integrin–ligand binding
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Articles

Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1

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A. Paul MOULD, Alistair N. GARRATT, Wilma PUZON-McLAUGHLIN, Yoshikazu TAKADA, Martin J. HUMPHRIES
Journal: Biochemical Journal
Biochem J (1998) 331 (3): 821–828.
https://doi.org/10.1042/bj3310821
Published: 01 May 1998
View articletitled, Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1
Open the PDF for Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1 in another window