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Articles

Role of protein synthesis and of fatty acid metabolism in the longer-term regulation of pyruvate dehydrogenase kinase

D A Priestman, S C Mistry, A Halsall, P J Randle

Biochem J (1994) 300 (3): 659–664.

https://doi.org/10.1042/bj3000659

Published: 15 June 1994

View articletitled, Role of protein synthesis and of fatty acid metabolism in the longer-term regulation of pyruvate dehydrogenase kinase

Articles

An improved assay for pyruvate dehydrogenase in liver and heart

P J Randle

Biochem J (1992) 284 (2): 605–608.

https://doi.org/10.1042/bj2840605

Published: 01 June 1992

View articletitled, An improved assay for pyruvate dehydrogenase in liver and heart

Articles

Evidence that rat liver pyruvate dehydrogenase kinase activator protein is a pyruvate dehydrogenase kinase

S C Mistry, D A Priestman, A L Kerbey, P J Randle

Biochem J (1991) 275 (3): 775–779.

https://doi.org/10.1042/bj2750775

Published: 01 May 1991

View articletitled, Evidence that rat liver pyruvate dehydrogenase kinase activator protein is a pyruvate dehydrogenase kinase

Articles

Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat cardiac myocytes

D R Marchington, A L Kerbey, P J Randle

Biochem J (1990) 267 (1): 245–247.

https://doi.org/10.1042/bj2670245

Published: 01 April 1990

View articletitled, Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat cardiac myocytes

Articles

Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat hepatocytes

D R Marchington, A L Kerbey, M G Giardina, A E Jones, P J Randle

Biochem J (1989) 257 (2): 487–491.

https://doi.org/10.1042/bj2570487

Published: 15 January 1989

View articletitled, Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat hepatocytes

Articles

Longer-term regulation of branched-chain-2-oxoacid dehydrogenase complex studied in rat hepatocytes in culture

M Beggs, J M Shaw, P J Randle

Biochem J (1989) 257 (1): 271–275.

https://doi.org/10.1042/bj2570271

Published: 01 January 1989

View articletitled, Longer-term regulation of branched-chain-2-oxoacid dehydrogenase complex studied in rat hepatocytes in culture

Articles

Activity of branched-chain 2-oxo acid dehydrogenase complex in rat liver mitochondria and in rat liver

M Beggs, P J Randle

Biochem J (1988) 256 (3): 929–934.

https://doi.org/10.1042/bj2560929

Published: 15 December 1988

View articletitled, Activity of branched-chain 2-oxo acid dehydrogenase complex in rat liver mitochondria and in rat liver

Articles

Insulin reverses effects of starvation on the activity of pyruvate dehydrogenase kinase in cultured hepatocytes

D R Marchington, A L Kerbey, A E Jones, P J Randle

Biochem J (1987) 246 (1): 233–236.

https://doi.org/10.1042/bj2460233

Published: 15 August 1987

View articletitled, Insulin reverses effects of starvation on the activity of pyruvate dehydrogenase kinase in cultured hepatocytes

Articles

Kinase activator protein mediates longer-term effects of starvation on activity of pyruvate dehydrogenase kinase in rat liver mitochondria

G S Denyer, A L Kerbey, P J Randle

Biochem J (1986) 239 (2): 347–354.

https://doi.org/10.1042/bj2390347

Published: 15 October 1986

View articletitled, Kinase activator protein mediates longer-term effects of starvation on activity of pyruvate dehydrogenase kinase in rat liver mitochondria

Articles

Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart

J Espinal, M Beggs, H Patel, P J Randle

Biochem J (1986) 237 (1): 285–288.

https://doi.org/10.1042/bj2370285

Published: 01 July 1986

View articletitled, Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart

Articles

Rat tissue concentrations of branched-chain 2-oxo acid dehydrogenase complex. Re-evaluation by immunoassay and bioassay

P A Patston, J Espinal, J M Shaw, P J Randle

Biochem J (1986) 235 (2): 429–434.

https://doi.org/10.1042/bj2350429

Published: 15 April 1986

View articletitled, Rat tissue concentrations of branched-chain 2-oxo acid dehydrogenase complex. Re-evaluation by immunoassay and bioassay

Articles

Modulation of pyruvate dehydrogenase kinase activity in cultured hepatocytes by glucagon and n -octanoate

H R Fatania, T C Vary, P J Randle

Biochem J (1986) 234 (1): 233–236.

https://doi.org/10.1042/bj2340233

Published: 15 February 1986

View articletitled, Modulation of pyruvate dehydrogenase kinase activity in cultured hepatocytes by glucagon and n -octanoate

Articles

Pyruvate dehydrogenase kinase activity of pig heart pyruvate dehydrogenase (E1 component of pyruvate dehydrogenase complex)

A L Kerbey, P J Randle

Biochem J (1985) 231 (3): 523–529.

https://doi.org/10.1042/bj2310523

Published: 01 November 1985

View articletitled, Pyruvate dehydrogenase kinase activity of pig heart pyruvate dehydrogenase (E1 component of pyruvate dehydrogenase complex)

Articles

Purification and properties of a protein activator of phosphorylated branched-chain 2-oxo acid dehydrogenase complex

J Espinal, P A Patston, H R Fatania, K S Lau, P J Randle

Biochem J (1985) 225 (2): 509–516.

https://doi.org/10.1042/bj2250509

Published: 15 January 1985

View articletitled, Purification and properties of a protein activator of phosphorylated branched-chain 2-oxo acid dehydrogenase complex

Articles

Effects of diet and of alloxan-diabetes on the activity of branched-chain 2-oxo acid dehydrogenase complex and of activator protein in rat tissues

P A Patston, J Espinal, P J Randle

Biochem J (1984) 222 (3): 711–719.

https://doi.org/10.1042/bj2220711

Published: 15 September 1984

View articletitled, Effects of diet and of alloxan-diabetes on the activity of branched-chain 2-oxo acid dehydrogenase complex and of activator protein in rat tissues

Articles

Studies on rat parotid-cell actomyosin

T Kealey, P J Randle

Biochem J (1984) 220 (1): 291–299.

https://doi.org/10.1042/bj2200291

Published: 15 May 1984

View articletitled, Studies on rat parotid-cell actomyosin

Articles

Reversible phosphorylation of pyruvate dehydrogenase in rat skeletal-muscle mitochondria. Effects of starvation and diabetes

S J Fuller, P J Randle

Biochem J (1984) 219 (2): 635–646.

https://doi.org/10.1042/bj2190635

Published: 15 April 1984

View articletitled, Reversible phosphorylation of pyruvate dehydrogenase in rat skeletal-muscle mitochondria. Effects of starvation and diabetes

Articles

Occupancy of phosphorylation sites in pyruvate dehydrogenase phosphate complex in rat heart in vivo . Relation to proportion of inactive complex and rate of re-activation by phosphatase

G J Sale, P J Randle

Biochem J (1982) 206 (2): 221–229.

https://doi.org/10.1042/bj2060221

Published: 15 August 1982

View articletitled, Occupancy of phosphorylation sites in pyruvate dehydrogenase phosphate complex in rat heart in vivo . Relation to proportion of inactive complex and rate of re-activation by phosphatase

Articles

Pyruvate dehydrogenase kinase/activator in rat heart mitochondria, Assay, effect of starvation, and effect of protein-synthesis inhibitors of starvation

A L Kerbey, P J Randle

Biochem J (1982) 206 (1): 103–111.

https://doi.org/10.1042/bj2060103

Published: 15 July 1982

View articletitled, Pyruvate dehydrogenase kinase/activator in rat heart mitochondria, Assay, effect of starvation, and effect of protein-synthesis inhibitors of starvation

Articles

Dephosphorylation of pig heart pyruvate dehydrogenase phosphate complexes by pig heart pyruvate dehydrogenase phosphate phosphatase

A L Kerbey, P J Randle, A Kearns

Biochem J (1981) 195 (1): 51–59.

https://doi.org/10.1042/bj1950051

Published: 01 April 1981

View articletitled, Dephosphorylation of pig heart pyruvate dehydrogenase phosphate complexes by pig heart pyruvate dehydrogenase phosphate phosphatase

Articles

Occupancy of sites of phosphorylation in inactive rat heart pyruvate dehydrogenase phosphate in vivo

G J Sale, P J Randle

Biochem J (1981) 193 (3): 935–946.

https://doi.org/10.1042/bj1930935

Published: 01 March 1981

View articletitled, Occupancy of sites of phosphorylation in inactive rat heart pyruvate dehydrogenase phosphate in vivo

Articles

Incorporation of [ 32 P]phosphate into the pyruvate dehydrogenase complex in rat heart mitochondria

G J Sale, P J Randle

Biochem J (1980) 188 (2): 409–421.

https://doi.org/10.1042/bj1880409

Published: 15 May 1980

View articletitled, Incorporation of [ 32 P]phosphate into the pyruvate dehydrogenase complex in rat heart mitochondria

Articles

Amino acid sequences around the sites of phosphorylation in the pig heart pyruvate dehydrogenase complex

P H Sugden, A L Kerbey, P J Randle, C A Waller, K B M Reid

Biochem J (1979) 181 (2): 419–426.

https://doi.org/10.1042/bj1810419

Published: 01 August 1979

View articletitled, Amino acid sequences around the sites of phosphorylation in the pig heart pyruvate dehydrogenase complex

Articles

Regulation of kinase reactions in pig heart pyruvate dehydrogenase complex

A L Kerbey, P M Radcliffe, P J Randle, P H Sugden

Biochem J (1979) 181 (2): 427–433.

https://doi.org/10.1042/bj1810427

Published: 01 August 1979

View articletitled, Regulation of kinase reactions in pig heart pyruvate dehydrogenase complex

Articles

Conversion of inactive (phosphorylated) pyruvate dehydrogenase complex into active complex by the phosphate reaction in heart mitochondria is inhibited by alloxan-diabetes or starvation in the rat

N J Hutson, A L Kerbey, P J Randle, P H Sugden

Biochem J (1978) 173 (2): 669–680.

https://doi.org/10.1042/bj1730669

Published: 01 August 1978

View articletitled, Conversion of inactive (phosphorylated) pyruvate dehydrogenase complex into active complex by the phosphate reaction in heart mitochondria is inhibited by alloxan-diabetes or starvation in the rat

Articles

Partial purification and properties of branched-chain 2-oxo acid dehydrogenase of ox liver

P J Parker, P J Randle

Biochem J (1978) 171 (3): 751–757.

https://doi.org/10.1042/bj1710751

Published: 01 June 1978

View articletitled, Partial purification and properties of branched-chain 2-oxo acid dehydrogenase of ox liver

Articles

Calcium metabolism in rat hepatocytes

S Foden, P J Randle

Biochem J (1978) 170 (3): 615–625.

https://doi.org/10.1042/bj1700615

Published: 15 March 1978

View articletitled, Calcium metabolism in rat hepatocytes

Articles

Inhibition of lactate glucogneogenesis in rat kidney by dichloroacetate

J H Lacey, P J Randle

Biochem J (1978) 170 (3): 551–560.

https://doi.org/10.1042/bj1700551

Published: 15 March 1978

View articletitled, Inhibition of lactate glucogneogenesis in rat kidney by dichloroacetate

Articles

Phosphorylation of additional sites on pyruvate dehydrogenase inhibits its re-activation by pyruvate dehydrogenase phosphate phosphatase

P H Sugden, N J Hutson, A L Kerbey, P J Randle

Biochem J (1978) 169 (2): 433–435.

https://doi.org/10.1042/bj1690433

Published: 01 February 1978

View articletitled, Phosphorylation of additional sites on pyruvate dehydrogenase inhibits its re-activation by pyruvate dehydrogenase phosphate phosphatase

Articles

Diabetes and the control of pyruvate dehydrogenase in rat heart mitochondria by concentration ratios of adenosine triphosphate/adenosine diphosphate, of reduced/oxidized nicotinamide-adenine dinucleotide and of acetyl-coenzyme A/coenzyme A.

A L Kerbey, P M Radcliffe, P J Randle

Biochem J (1977) 164 (3): 509–519.

https://doi.org/10.1042/bj1640509

Published: 15 June 1977

View articletitled, Diabetes and the control of pyruvate dehydrogenase in rat heart mitochondria by concentration ratios of adenosine triphosphate/adenosine diphosphate, of reduced/oxidized nicotinamide-adenine dinucleotide and of acetyl-coenzyme A/coenzyme A.

Articles

Calcium metabolism and amylase release in rat parotid acinar cells

P Kanagasuntheram, P J Randle

Biochem J (1976) 160 (3): 547–564.

https://doi.org/10.1042/bj1600547

Published: 15 December 1976

View articletitled, Calcium metabolism and amylase release in rat parotid acinar cells

Articles

Carcass glycogen as a potential source of glucose during short-term starvation

M C Sugden, S C Sharples, P J Randle

Biochem J (1976) 160 (3): 817–819.

https://doi.org/10.1042/bj1600817

Published: 15 December 1976

View articletitled, Carcass glycogen as a potential source of glucose during short-term starvation

Articles

The elementary reactions of the pig heart pyruvate dehydrogenase complex. A study of the inhibition by phosphorylation

D A Walsh, R H Cooper, R M Denton, B J Bridges, P J Randle

Biochem J (1976) 157 (1): 41–67.

https://doi.org/10.1042/bj1570041

Published: 01 July 1976

View articletitled, The elementary reactions of the pig heart pyruvate dehydrogenase complex. A study of the inhibition by phosphorylation

Articles

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide

A L. Kerbey, P J. Randle, R H. Cooper, S Whitehouse, H T. Pask, R M. Denton

Biochem J (1976) 154 (2): 327–348.

https://doi.org/10.1042/bj1540327

Published: 15 February 1976

View articletitled, Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide

Articles

Exchangeable and total calcium pools in mitochondria of rat epididymal fat-pads and isolated fat-cells. Role in the regulation of pyruvate dehydrogenase activity

D L Severson, R M Denton, B J Bridges, P J Randle

Biochem J (1976) 154 (1): 209–223.

https://doi.org/10.1042/bj1540209

Published: 15 January 1976

View articletitled, Exchangeable and total calcium pools in mitochondria of rat epididymal fat-pads and isolated fat-cells. Role in the regulation of pyruvate dehydrogenase activity

Articles

Regulation of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads. Effects of starvation, alloxan-diabetes and high-fat diet

D Stansbie, R M Denton, B J Bridges, H T Pask, P J Randle

Biochem J (1976) 154 (1): 225–236.

https://doi.org/10.1042/bj1540225

Published: 15 January 1976

View articletitled, Regulation of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads. Effects of starvation, alloxan-diabetes and high-fat diet

Articles

Concentration of adenosine 3′:5′-cyclic monophosphate in mouse pancreatic islets measured by a protein-binding radioassay

R. H. Cooper, S. J. H. Ashcroft, P. J. Randle

Biochem J (1973) 134 (2): 599–605.

https://doi.org/10.1042/bj1340599

Published: 01 June 1973

View articletitled, Concentration of adenosine 3′:5′-cyclic monophosphate in mouse pancreatic islets measured by a protein-binding radioassay

Articles

Mechanisms regulating adipose-tissue pyruvate dehydrogenase

B. R. Martin, R. M. Denton, H. T. Pask, P. J. Randle

Biochem J (1972) 129 (3): 763–773.

https://doi.org/10.1042/bj1290763

Published: 01 September 1972

View articletitled, Mechanisms regulating adipose-tissue pyruvate dehydrogenase

Articles

The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart

J. R. Neely, R. M. Denton, P. J. England, P. J. Randle

Biochem J (1972) 128 (1): 147–159.

https://doi.org/10.1042/bj1280147

Published: 01 June 1972

View articletitled, The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart

Articles

Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

R M Denton, P J Randle, B R Martin

Biochem J (1972) 128 (1): 161–163.

https://doi.org/10.1042/bj1280161

Published: 01 June 1972

View articletitled, Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

Articles

The pentose cycle and insulin release in mouse pancreatic islets

S. J. H. Ashcroft, L. C. C. Weerasinghe, J. M. Bassett, P. J. Randle

Biochem J (1972) 126 (3): 525–532.

https://doi.org/10.1042/bj1260525

Published: 01 February 1972

View articletitled, The pentose cycle and insulin release in mouse pancreatic islets

Articles

Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones

H. G. Coore, R. M. Denton, B. R. Martin, P. J. Randle

Biochem J (1971) 125 (1): 115–127.

https://doi.org/10.1042/bj1250115

Published: 01 November 1971

View articletitled, Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones

Articles

Properties of pyruvate dehydrogenase from fat-cell mitochondria and its hormonal control

R M Denton, B R Martin, H G Coore, P J Randle

Biochem J (1971) 123 (4): 39P.

https://doi.org/10.1042/bj1230039Pb

Published: 01 July 1971

View articletitled, Properties of pyruvate dehydrogenase from fat-cell mitochondria and its hormonal control

Articles

Effects of insulin and adrenaline on rat epididymal-fat-pad pyruvate dehydrogenase

H G Coore, R M Denton, B R Martin, P J Randle

Biochem J (1971) 123 (4): 38P–39P.

https://doi.org/10.1042/bj1230038Pb

Published: 01 July 1971

View articletitled, Effects of insulin and adrenaline on rat epididymal-fat-pad pyruvate dehydrogenase

Articles

Enzymes of glucose metabolism in normal mouse pancreatic islets

S. J. H. Ashcroft, P. J. Randle

Biochem J (1970) 119 (1): 5–15.

https://doi.org/10.1042/bj1190005

Published: 01 August 1970

View articletitled, Enzymes of glucose metabolism in normal mouse pancreatic islets

Articles

Glucose metabolism in mouse pancreatic islets

S. J. H. Ashcroft, C. J. Hedeskov, P. J. Randle

Biochem J (1970) 118 (1): 143–154.

https://doi.org/10.1042/bj1180143

Published: 01 June 1970

View articletitled, Glucose metabolism in mouse pancreatic islets

Articles

Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart

P. J. Randle, P. J. England, R. M. Denton

Biochem J (1970) 117 (4): 677–695.

https://doi.org/10.1042/bj1170677

Published: 01 May 1970

View articletitled, Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart

Articles

Carbohydrate metabolism in pancreatic islets and the release of insulin

P J Randle, S J H Ashcroft

Biochem J (1969) 112 (1): 1P–2P.

https://doi.org/10.1042/bj1120001P

Published: 01 March 1969

View articletitled, Carbohydrate metabolism in pancreatic islets and the release of insulin

Articles

Glucose phosphorylation in mouse pancreatic islets

S J Ashcroft, P J Randle

Biochem J (1968) 107 (4): 599–600.

https://doi.org/10.1042/bj1070599

Published: 01 April 1968

View articletitled, Glucose phosphorylation in mouse pancreatic islets

Articles

Effectors of rat-heart hexokinases and the control of rates of glucose phosphorylation in the perfused rat heart

P J England, P J Randle

Biochem J (1967) 105 (3): 907–920.

https://doi.org/10.1042/bj1050907

Published: 01 December 1967

View articletitled, Effectors of rat-heart hexokinases and the control of rates of glucose phosphorylation in the perfused rat heart

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