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Articles

Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to 7,12-dimethylbenz[ a ]-anthracene

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P. Sims
Journal: Biochemical Journal
Biochem J (1973) 131 (2): 405–413.
https://doi.org/10.1042/bj1310405
Published: 01 February 1973
View article titled, Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to 7,12-dimethylbenz[ a ]-anthracene
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Articles

Epoxy derivatives of aromatic polycyclic hydrocarbons. The synthesis of dibenz[ a,c ]anthracene 10,11-oxide and its metabolism by rat liver preparations

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P. Sims
Journal: Biochemical Journal
Biochem J (1972) 130 (1): 27–35.
https://doi.org/10.1042/bj1300027
Published: 01 November 1972
View article titled, Epoxy derivatives of aromatic polycyclic hydrocarbons. The synthesis of dibenz[ a,c ]anthracene 10,11-oxide and its metabolism by rat liver preparations
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Articles

Reactions of ‘K’-region epoxides of polycyclic hydrocarbons with nucleic acids and polyribonucleotides

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P L Grover, P Sims
Journal: Biochemical Journal
Biochem J (1972) 129 (3): 41P.
https://doi.org/10.1042/bj1290041Pa
Published: 01 September 1972
View article titled, Reactions of ‘K’-region epoxides of polycyclic hydrocarbons with nucleic acids and polyribonucleotides
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Articles

The formation of an epoxide in the microsomal metabolism of 7,12-dimethylbenz[ a ]anthracene

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G R Keysell, J Booth, P Sims, P L Grover, A Hewer
Journal: Biochemical Journal
Biochem J (1972) 129 (3): 41P–42P.
https://doi.org/10.1042/bj1290041Pb
Published: 01 September 1972
View article titled, The formation of an epoxide in the microsomal metabolism of 7,12-dimethylbenz[ a ]anthracene
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Articles

Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to benzo[ a ]pyrene and to 7,8- and 9,10-dihydrobenzo[ a ]pyrene

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J. F. Waterfall, P. Sims
Journal: Biochemical Journal
Biochem J (1972) 128 (2): 265–277.
https://doi.org/10.1042/bj1280265
Published: 01 June 1972
View article titled, Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to benzo[ a ]pyrene and to 7,8- and 9,10-dihydrobenzo[ a ]pyrene
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Articles

Mutagenicity of ‘K-region’ epoxides of polycyclic hydrocarbons towards bacteriophage T2

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M J Cookson, P L Grover, P Sims
Journal: Biochemical Journal
Biochem J (1971) 125 (4): 100P–101P.
https://doi.org/10.1042/bj1250100Pb
Published: 01 December 1971
View article titled, Mutagenicity of ‘K-region’ epoxides of polycyclic hydrocarbons towards bacteriophage T2
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Articles

Formation of epoxides as microsomal metabolites of polycyclic hydrocarbons

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P Sims, A Hewer, P L Grover
Journal: Biochemical Journal
Biochem J (1971) 125 (2): 28P.
https://doi.org/10.1042/bj1250028Pa
Published: 01 November 1971
View article titled, Formation of epoxides as microsomal metabolites of polycyclic hydrocarbons
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Articles

Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation of benz[ a ]anthracene 8,9-oxide and 10,11-dihydrobenz[ a ]anthracene 8,9-oxide and their metabolism by rat liver preparations

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P. Sims
Journal: Biochemical Journal
Biochem J (1971) 125 (1): 159–168.
https://doi.org/10.1042/bj1250159
Published: 01 November 1971
View article titled, Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation of benz[ a ]anthracene 8,9-oxide and 10,11-dihydrobenz[ a ]anthracene 8,9-oxide and their metabolism by rat liver preparations
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Articles

Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro

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P L Grover, P Sims
Journal: Biochemical Journal
Biochem J (1968) 110 (1): 159–160.
https://doi.org/10.1042/bj1100159
Published: 01 November 1968
View article titled, Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro
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Articles

The metabolism of 7- and 12-methylbenz[ a ]-anthracene and their derivatives

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P Sims
Journal: Biochemical Journal
Biochem J (1967) 105 (2): 591–598.
https://doi.org/10.1042/bj1050591
Published: 01 November 1967
View article titled, The metabolism of 7- and 12-methylbenz[ a ]-anthracene and their derivatives
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Articles

The effect of pretreatment with adrenal-protecting compounds on the metabolism of 7,12-dimethylbenz[ a ]anthracene and related compounds by rat-liver homogenates

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E Boyland, P Sims
Journal: Biochemical Journal
Biochem J (1967) 104 (2): 394–403.
https://doi.org/10.1042/bj1040394
Published: 01 August 1967
View article titled, The effect of pretreatment with adrenal-protecting compounds on the metabolism of 7,12-dimethylbenz[ a ]anthracene and related compounds by rat-liver homogenates
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Articles

The metabolism of 3-methylcholanthrene and some related compounds by rat-liver homogenates

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P Sims
Journal: Biochemical Journal
Biochem J (1966) 98 (1): 215–228.
https://doi.org/10.1042/bj0980215
Published: 01 January 1966
View article titled, The metabolism of 3-methylcholanthrene and some related compounds by rat-liver homogenates
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Articles

The metabolism of benz[ a ]anthracene and dibenz[ a,h ]anthracene and their 5,6-epoxy-5,6-dihydro derivatives by rat-liver homogenates

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E Boyland, P Sims
Journal: Biochemical Journal
Biochem J (1965) 97 (1): 7–16.
https://doi.org/10.1042/bj0970007
Published: 01 October 1965
View article titled, The metabolism of benz[ a ]anthracene and dibenz[ a,h ]anthracene and their 5,6-epoxy-5,6-dihydro derivatives by rat-liver homogenates
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Articles

The metabolism of γ-2,3,4,5,6-pentachlorocyclohex-1-ene and γ-hexachlorocyclohexane in rats

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PL Grover, P Sims
Journal: Biochemical Journal
Biochem J (1965) 96 (2): 521–525.
https://doi.org/10.1042/bj0960521
Published: 01 August 1965
View article titled, The metabolism of γ-2,3,4,5,6-pentachlorocyclohex-1-ene and γ-hexachlorocyclohexane in rats
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Articles

METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 1,4-EPOXY-1,4-DIHYDRONAPHTHALENE IN RATS

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P SIMS
Journal: Biochemical Journal
Biochem J (1965) 95 (3): 608–611.
https://doi.org/10.1042/bj0950608
Published: 01 June 1965
View article titled, METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 1,4-EPOXY-1,4-DIHYDRONAPHTHALENE IN RATS
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METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 7,12-DIMETHYLBENZ[α]ANTHRACENE BY RAT-LIVER HOMOGENATES

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E BOYLAND, P SIMS
Journal: Biochemical Journal
Biochem J (1965) 95 (3): 780–787.
https://doi.org/10.1042/bj0950780
Published: 01 June 1965
View article titled, METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 7,12-DIMETHYLBENZ[α]ANTHRACENE BY RAT-LIVER HOMOGENATES
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Articles

METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 9,10-EPOXY-9,10-DIHYDROPHENANTHRENE IN RATS

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E BOYLAND, P SIMS
Journal: Biochemical Journal
Biochem J (1965) 95 (3): 788–792.
https://doi.org/10.1042/bj0950788
Published: 01 June 1965
View article titled, METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 9,10-EPOXY-9,10-DIHYDROPHENANTHRENE IN RATS
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Articles

CONJUGATIONS WITH GLUTATHIONE. THE ENZYMIC CONJUGATION OF SOME CHLOROCYCLOHEXENES

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P SIMS, PL GROVER
Journal: Biochemical Journal
Biochem J (1965) 95 (1): 156–160.
https://doi.org/10.1042/bj0950156
Published: 01 April 1965
View article titled, CONJUGATIONS WITH GLUTATHIONE. THE ENZYMIC CONJUGATION OF SOME CHLOROCYCLOHEXENES
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Articles

Metabolism of polycyclic compounds. 26. The hydroxylation of some aromatic hydrocarbons by the ascorbic acid model hydroxylating system and by rat-liver microsomes

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E Boyland, M Kimura, P Sims
Journal: Biochemical Journal
Biochem J (1964) 92 (3): 631–638.
https://doi.org/10.1042/bj0920631
Published: 01 September 1964
View article titled, Metabolism of polycyclic compounds. 26. The hydroxylation of some aromatic hydrocarbons by the ascorbic acid model hydroxylating system and by rat-liver microsomes
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Articles

Metabolism of polycyclic compounds. 25. The metabolism of anthracene and some related compounds in rats

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P Sims
Journal: Biochemical Journal
Biochem J (1964) 92 (3): 621–631.
https://doi.org/10.1042/bj0920621
Published: 01 September 1964
View article titled, Metabolism of polycyclic compounds. 25. The metabolism of anthracene and some related compounds in rats
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Articles

Metabolism of polycyclic compounds. 24. The metabolism of benz[α]anthracene

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E Boyland, P Sims
Journal: Biochemical Journal
Biochem J (1964) 91 (3): 493–506.
https://doi.org/10.1042/bj0910493
Published: 01 June 1964
View article titled, Metabolism of polycyclic compounds. 24. The metabolism of benz[α]anthracene
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Articles

Conjugations with glutathione. Distribution of glutathione S -aryltransferase in vertebrate species

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PL Grover, P Sims
Journal: Biochemical Journal
Biochem J (1964) 90 (3): 603–606.
https://doi.org/10.1042/bj0900603
Published: 01 March 1964
View article titled, Conjugations with glutathione. Distribution of glutathione S -aryltransferase in vertebrate species
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Articles

Metabolism of polycyclic compounds. 23. The metabolism of pyrene in rats and rabbits

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E Boyland, P Sims
Journal: Biochemical Journal
Biochem J (1964) 90 (2): 391–398.
https://doi.org/10.1042/bj0900391
Published: 01 February 1964
View article titled, Metabolism of polycyclic compounds. 23. The metabolism of pyrene in rats and rabbits
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Articles

An enzyme from rat liver catalysing conjugations with glutathione

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J. Booth, E. Boyland, P. Sims
Journal: Biochemical Journal
Biochem J (1962) 85 (3): 417_b1.
https://doi.org/10.1042/BJ0850417_b1a
Published: 01 December 1962
View article titled, An enzyme from rat liver catalysing conjugations with glutathione
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Articles

Metabolism of polycyclic compounds. 20. The metabolism of phenanthrene in rabbits and rats: mercapturic acids and related compounds

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E BOYLAND, P SIMS
Journal: Biochemical Journal
Biochem J (1962) 84 (3): 564–570.
https://doi.org/10.1042/bj0840564
Published: 01 September 1962
View article titled, Metabolism of polycyclic compounds. 20. The metabolism of phenanthrene in rabbits and rats: mercapturic acids and related compounds
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Articles

Metabolism of polycyclic compounds. 21. The metabolism of phenanthrene in rabbits and rats: dihydrodihydroxy compounds and related glucosiduronic acids

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E BOYLAND, P SIMS
Journal: Biochemical Journal
Biochem J (1962) 84 (3): 571–582.
https://doi.org/10.1042/bj0840571
Published: 01 September 1962
View article titled, Metabolism of polycyclic compounds. 21. The metabolism of phenanthrene in rabbits and rats: dihydrodihydroxy compounds and related glucosiduronic acids
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Metabolism of polycyclic compounds. 22. The metabolism of (±)- trans -9,10-dihydro-9,10-dihydroxyphenanthrene in rats

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E BOYLAND, P SIMS
Journal: Biochemical Journal
Biochem J (1962) 84 (3): 583–586.
https://doi.org/10.1042/bj0840583
Published: 01 September 1962
View article titled, Metabolism of polycyclic compounds. 22. The metabolism of (±)- trans -9,10-dihydro-9,10-dihydroxyphenanthrene in rats
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Metabolism of polycyclic compounds. 19. The metabolism of phenanthrene in rabbits and rats: phenols and sulphuric esters

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P SIMS
Journal: Biochemical Journal
Biochem J (1962) 84 (3): 558–563.
https://doi.org/10.1042/bj0840558
Published: 01 September 1962
View article titled, Metabolism of polycyclic compounds. 19. The metabolism of phenanthrene in rabbits and rats: phenols and sulphuric esters
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Articles

An enzyme from rat liver catalysing conjugations with glutathione

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J. Booth, E. Boyland, P Sims
Journal: Biochemical Journal
Biochem J (1961) 79 (3): 516–524.
https://doi.org/10.1042/bj0790516
Published: 01 June 1961
View article titled, An enzyme from rat liver catalysing conjugations with glutathione
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Metabolism of polycyclic compounds. 18. The secretion of metabolites of naphthalene, 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene in rat bile

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E. Boyland, G. S. Ramsay, P Sims
Journal: Biochemical Journal
Biochem J (1961) 78 (2): 376–384.
https://doi.org/10.1042/bj0780376
Published: 01 February 1961
View article titled, Metabolism of polycyclic compounds. 18. The secretion of metabolites of naphthalene, 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene in rat bile
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Metabolism of polycyclic compounds. 16. The metabolism of 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene

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E. Boyland, P. Sims
Journal: Biochemical Journal
Biochem J (1960) 77 (1): 175–181.
https://doi.org/10.1042/bj0770175
Published: 01 October 1960
View article titled, Metabolism of polycyclic compounds. 16. The metabolism of 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene
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Metabolism of polycyclic compounds. 17. The reaction of 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene with glutathione catalysed by tissue preparations

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J. Booth, E. Boyland, T. Sato, P. Sims
Journal: Biochemical Journal
Biochem J (1960) 77 (1): 182–186.
https://doi.org/10.1042/bj0770182
Published: 01 October 1960
View article titled, Metabolism of polycyclic compounds. 17. The reaction of 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene with glutathione catalysed by tissue preparations
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Metabolism of polycyclic compounds. 15. The conversion of naphthalene into a derivative of glutathione by rat-liver slices

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J. Booth, E. Boyland, P Sims
Journal: Biochemical Journal
Biochem J (1960) 74 (1): 117–122.
https://doi.org/10.1042/bj0740117
Published: 01 January 1960
View article titled, Metabolism of polycyclic compounds. 15. The conversion of naphthalene into a derivative of glutathione by rat-liver slices
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Metabolism of polycyclic compounds. 14. The conversion of naphthalene into compounds related to trans -1:2-dihydro-1:2-dihydroxynaphthalene by rabbits

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P Sims
Journal: Biochemical Journal
Biochem J (1959) 73 (3): 389–395.
https://doi.org/10.1042/bj0730389
Published: 01 November 1959
View article titled, Metabolism of polycyclic compounds. 14. The conversion of naphthalene into compounds related to trans -1:2-dihydro-1:2-dihydroxynaphthalene by rabbits
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The biochemistry of aromatic amines. 6. The metabolism of 3:4-dimethylaniline in rats

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E. Boyland, P Sims
Journal: Biochemical Journal
Biochem J (1959) 73 (2): 377–380.
https://doi.org/10.1042/bj0730377
Published: 01 October 1959
View article titled, The biochemistry of aromatic amines. 6. The metabolism of 3:4-dimethylaniline in rats
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Metabolism of polycyclic compounds. 12. An acid-labile precursor of 1-naphthylmercapturic acid and naphthol: an N-acetyl-S- (1:2-dihydrohydroxynaphthyl)-l-cysteine*

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E. Boyland, P. Sims
Journal: Biochemical Journal
Biochem J (1958) 68 (3): 440–447.
https://doi.org/10.1042/bj0680440
Published: 01 March 1958
View article titled, Metabolism of polycyclic compounds. 12. An acid-labile precursor of 1-naphthylmercapturic acid and naphthol: an N-acetyl-S- (1:2-dihydrohydroxynaphthyl)-l-cysteine*
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Metabolism of polycyclic compounds. 11. The conversion of naphthalene into 2-hydroxy-1-naphthyl sulphate in the rabbit

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E. Boyland, P. Sims
Journal: Biochemical Journal
Biochem J (1957) 66 (1): 38–40.
https://doi.org/10.1042/bj0660038
Published: 01 May 1957
View article titled, Metabolism of polycyclic compounds. 11. The conversion of naphthalene into 2-hydroxy-1-naphthyl sulphate in the rabbit
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The oxidation of tryptophan and some related compounds with persulphate

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E. Boyland, P. Sims, D. C. Williams
Journal: Biochemical Journal
Biochem J (1956) 62 (4): 546–550.
https://doi.org/10.1042/bj0620546
Published: 01 April 1956
View article titled, The oxidation of tryptophan and some related compounds with persulphate
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The biochemistry of aromatic amines. The resistance of some o -aminoaryl sulphates to hydrolysis by aryl sulphatases

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E. Boyland, D. Manson, P. Sims, D. C. Williams
Journal: Biochemical Journal
Biochem J (1956) 62 (1): 68–71.
https://doi.org/10.1042/bj0620068
Published: 01 January 1956
View article titled, The biochemistry of aromatic amines. The resistance of some o -aminoaryl sulphates to hydrolysis by aryl sulphatases
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