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Patrick MASSON
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Articles

Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment

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Alexandra D. Kharlamova, Sofya V. Lushchekina, Konstantin A. Petrov, Ekaterina D. Kots, Florian Nachon, Marielle Villard-Wandhammer, Irina V. Zueva, Eric Krejci, Vladimir S. Reznik, Vladimir V. Zobov, Evgeny E. Nikolsky, Patrick Masson
Journal: Biochemical Journal
Biochem J (2016) 473 (9): 1225–1236.
https://doi.org/10.1042/BCJ20160084
Published: 26 April 2016
View articletitled, Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment
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Includes: Supplementary data
Articles

Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies

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Patrick Masson, Sofya Lushchekina, Lawrence M. Schopfer, Oksana Lockridge
Journal: Biochemical Journal
Biochem J (2013) 454 (3): 387–399.
https://doi.org/10.1042/BJ20130389
Published: 29 August 2013
View articletitled, Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies
Open the PDF for Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies in another window
Includes: Supplementary data
Articles

X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger

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Florian Nachon, Eugenie Carletti, Marielle Wandhammer, Yvain Nicolet, Lawrence M. Schopfer, Patrick Masson, Oksana Lockridge
Journal: Biochemical Journal
Biochem J (2011) 434 (1): 73–82.
https://doi.org/10.1042/BJ20101648
Published: 27 January 2011
View articletitled, X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger
Open the PDF for X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger in another window
Articles

Structure–activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun

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Eugénie Carletti, Nadine Aurbek, Emilie Gillon, Mélanie Loiodice, Yvain Nicolet, Juan-Carlos Fontecilla-Camps, Patrick Masson, Horst Thiermann, Florian Nachon, Franz Worek
Journal: Biochemical Journal
Biochem J (2009) 421 (1): 97–106.
https://doi.org/10.1042/BJ20090091
Published: 12 June 2009
View articletitled, Structure–activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun
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Articles

Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers

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He Li, Lawrence M. Schopfer, Patrick Masson, Oksana Lockridge
Journal: Biochemical Journal
Biochem J (2008) 411 (2): 425–432.
https://doi.org/10.1042/BJ20071551
Published: 27 March 2008
View articletitled, Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers
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Includes: Supplementary data
Articles

Contribution of the active-site metal cation to the catalytic activity and to the conformational stability of phosphotriesterase: temperature- and pH-dependence

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Daniel ROCHU, Nathalie VIGUIÉ, Frédérique RENAULT, David CROUZIER, Marie-Thérèse FROMENT, Patrick MASSON
Journal: Biochemical Journal
Biochem J (2004) 380 (3): 627–633.
https://doi.org/10.1042/bj20031861
Published: 15 June 2004
View articletitled, Contribution of the active-site metal cation to the catalytic activity and to the conformational stability of phosphotriesterase: temperature- and pH-dependence
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Articles

Pressure- and heat-induced inactivation of butyrylcholinesterase: evidence for multiple intermediates and the remnant inactivation process

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Alexandra WEINGAND-ZIADE, Fabien RIBES, Frédérique RENAULT, Patrick MASSON
Journal: Biochemical Journal
Biochem J (2001) 356 (2): 487–493.
https://doi.org/10.1042/bj3560487
Published: 24 May 2001
View articletitled, Pressure- and heat-induced inactivation of butyrylcholinesterase: evidence for multiple intermediates and the remnant inactivation process
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Articles

Hydration change during the aging of phosphorylated human butyrylcholinesterase: importance of residues aspartate-70 and glutamate-197 in the water network as probed by hydrostatic and osmotic pressures

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Patrick MASSON, Cécile CLÉRY, Patrice GUERRA, Arnaud REDSLOB, Christine ALBARET, Pierre-Louis FORTIER
Journal: Biochemical Journal
Biochem J (1999) 343 (2): 361–369.
https://doi.org/10.1042/bj3430361
Published: 08 October 1999
View articletitled, Hydration change during the aging of phosphorylated human butyrylcholinesterase: importance of residues aspartate-70 and glutamate-197 in the water network as probed by hydrostatic and osmotic pressures
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Articles

Two invertebrate acetylcholinesterases show activation followed by inhibition with substrate concentration

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Véronique MARCEL, Laurent Gagnoux PALACIOS, Christophe PERTUY, Patrick MASSON, Didier FOURNIER
Journal: Biochemical Journal
Biochem J (1998) 329 (2): 329–334.
https://doi.org/10.1042/bj3290329
Published: 15 January 1998
View articletitled, Two invertebrate acetylcholinesterases show activation followed by inhibition with substrate concentration
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Articles

Aging of di-isopropyl-phosphorylated human butyrylcholinesterase

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Patrick MASSON, Pierre-Louis FORTIER, Christine ALBARET, Marie-Thérèse FROMENT, F. Cynthia BARTELS, Oksana LOCKRIDGE
Journal: Biochemical Journal
Biochem J (1997) 327 (2): 601–607.
https://doi.org/10.1042/bj3270601
Published: 15 October 1997
View articletitled, Aging of di-isopropyl-phosphorylated human butyrylcholinesterase
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Articles

Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase

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Patrick MASSON, Marie-Thérèse FROMENT, Cynthia F. BARTELS, Oksana LOCKRIDGE
Journal: Biochemical Journal
Biochem J (1997) 325 (1): 53–61.
https://doi.org/10.1042/bj3250053
Published: 01 July 1997
View articletitled, Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase
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