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Peter J. CULLEN
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Articles

Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing

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Gabriela da SILVA XAVIER, Qingwen QIAN, Peter J. CULLEN, Guy A. RUTTER
Journal: Biochemical Journal
Biochem J (2004) 377 (1): 149–158.
https://doi.org/10.1042/bj20031260
Published: 01 January 2004
View articletitled, Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing
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Articles

Effects of elevated expression of inositol 1,4,5-trisphosphate 3-kinase B on Ca2+ homoeostasis in HeLa cells

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Tom H. MILLARD, Peter J. CULLEN, George BANTING
Journal: Biochemical Journal
Biochem J (2000) 352 (3): 709–715.
https://doi.org/10.1042/bj3520709
Published: 08 December 2000
View articletitled, Effects of elevated expression of inositol 1,4,5-trisphosphate 3-kinase B on Ca2+ homoeostasis in HeLa cells
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Articles

Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BP

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Gyles COZIER, Richard SESSIONS, Joanna R. BOTTOMLEY, Jon S. REYNOLDS, Peter J. CULLEN
Journal: Biochemical Journal
Biochem J (2000) 349 (1): 333–342.
https://doi.org/10.1042/bj3490333
Published: 26 June 2000
View articletitled, Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BP
Open the PDF for Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BP in another window
Articles

Signalling via ADP-ribosylation factor 6 lies downstream of phosphatidylinositide 3-kinase

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Kanamarlapudi VENKATESWARLU, Peter J. CULLEN
Journal: Biochemical Journal
Biochem J (2000) 345 (3): 719–724.
https://doi.org/10.1042/bj3450719
Published: 25 January 2000
View articletitled, Signalling via ADP-ribosylation factor 6 lies downstream of phosphatidylinositide 3-kinase
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Articles

Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes

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Paru B. OATEY, Kanamarlapudi VENKATESWARLU, Alan G. WILLIAMS, Laura M. FLETCHER, Emily J. FOULSTONE, Peter J. CULLEN, Jeremy M. TAVARÉ
Journal: Biochemical Journal
Biochem J (1999) 344 (2): 511–518.
https://doi.org/10.1042/bj3440511
Published: 24 November 1999
View articletitled, Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes
Open the PDF for Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes in another window
Includes: Supplementary data
Articles

Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1

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Kanamarlapudi VENKATESWARLU, Paru B. OATEY, Jeremy M. TAVARÉ, Trevor R. JACKSON, Peter J. CULLEN
Journal: Biochemical Journal
Biochem J (1999) 340 (2): 359–363.
https://doi.org/10.1042/bj3400359
Published: 25 May 1999
View articletitled, Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1
Open the PDF for Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1 in another window
Includes: Supplementary data
Articles

Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain

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Kanamarlapudi VENKATESWARLU, Frank GUNN-MOORE, Paru B. OATEY, Jeremy M. TAVARÉ, Peter J. CULLEN
Journal: Biochemical Journal
Biochem J (1998) 335 (1): 139–146.
https://doi.org/10.1042/bj3350139
Published: 01 October 1998
View articletitled, Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain
Open the PDF for Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain in another window
Includes: Supplementary data
Articles

Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by Ins(1,3,4,5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor

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Jefferson W. LOOMIS-HUSSELBEE, Christopher D. WALKER, Joanna R. BOTTOMLEY, Peter J. CULLEN, Robin F. IRVINE, Alan P. DAWSON
Journal: Biochemical Journal
Biochem J (1998) 331 (3): 947–952.
https://doi.org/10.1042/bj3310947
Published: 01 May 1998
View articletitled, Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by Ins(1,3,4,5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor
Open the PDF for Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by Ins(1,3,4,5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor in another window
Articles

Synergistic effects of inositol 1,3,4,5-tetrakisphosphate on inositol 2,4,5-triphosphate-stimulated Ca 2+ release do not involve direct interaction of inositol 1,3,4,5-tetrakisphosphate with inositol triphosphate-binding sites

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Jeff W. LOOMIS-HUSSELBEE, Peter J. CULLEN, Uschi E. DREIKHAUSEN, Robin F. IRVINE, Alan P. DAWSON
Journal: Biochemical Journal
Biochem J (1996) 314 (3): 811–816.
https://doi.org/10.1042/bj3140811
Published: 15 March 1996
View articletitled, Synergistic effects of inositol 1,3,4,5-tetrakisphosphate on inositol 2,4,5-triphosphate-stimulated Ca 2+ release do not involve direct interaction of inositol 1,3,4,5-tetrakisphosphate with inositol triphosphate-binding sites
Open the PDF for Synergistic effects of inositol 1,3,4,5-tetrakisphosphate on inositol 2,4,5-triphosphate-stimulated Ca 2+ release do not involve direct interaction of inositol 1,3,4,5-tetrakisphosphate with inositol triphosphate-binding sites in another window