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Articles

Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12

Elisha H. McCrory, Vyacheslav Akimov, Philip Cohen, Blagoy Blagoev

Biochem J (2022) 479 (23): 2419–2431.

https://doi.org/10.1042/BCJ20220510

Published: 07 December 2022

View articletitled, Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12

Includes: Supplementary data

Articles

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte, Philip Cohen

Biochem J (2022) 479 (20): 2195–2216.

https://doi.org/10.1042/BCJ20220401

Published: 21 October 2022

View articletitled, Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

Includes: Supplementary data

Articles

TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells

Melissa Rodrigues, Tsvetana Petrova, Brendan Tibbs, J. Simon C. Arthur, Philip Cohen

Biochem J (2022) 479 (17): 1891–1907.

https://doi.org/10.1042/BCJ20220314

Published: 16 September 2022

View articletitled, TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells

Includes: Supplementary data

Articles

Nuts and bolts of the salt-inducible kinases (SIKs)

Nicola J. Darling, Philip Cohen

Biochem J (2021) 478 (7): 1377–1397.

https://doi.org/10.1042/BCJ20200502

Published: 16 April 2021

View articletitled, Nuts and bolts of the salt-inducible kinases (SIKs)

Articles

Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3

Jiazhen Zhang, Thomas Macartney, Mark Peggie, Philip Cohen

Biochem J (2017) 474 (13): 2235–2248.

https://doi.org/10.1042/BCJ20170288

Published: 26 June 2017

View articletitled, Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3

Includes: Supplementary data

Articles

The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-like receptor agonists

Stefan Vollmer, Sam Strickson, Tinghu Zhang, Nathanael Gray, Katherine L. Lee, Vikram R. Rao, Philip Cohen

Biochem J (2017) 474 (12): 2027–2038.

https://doi.org/10.1042/BCJ20170097

Published: 06 June 2017

View articletitled, The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-like receptor agonists

Includes: Supplementary data

Articles

Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β

Siddharth Bakshi, Jordan Taylor, Sam Strickson, Thomas McCartney, Philip Cohen

Biochem J (2017) 474 (7): 1163–1174.

https://doi.org/10.1042/BCJ20160992

Published: 15 March 2017

View articletitled, Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β

Includes: Supplementary data

Articles

Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members

Nazma Malik, Stefan Vollmer, Sambit Kumar Nanda, Marta Lopez-Pelaez, Alan Prescott, Nathanael Gray, Philip Cohen

Biochem J (2015) 468 (3): 363–372.

https://doi.org/10.1042/BJ20141523

Published: 15 June 2015

View articletitled, Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members

Includes: Supplementary data

Articles

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation

Jiazhen Zhang, Kristopher Clark, Toby Lawrence, Mark W. Peggie, Philip Cohen

Biochem J (2014) 461 (3): 531–537.

https://doi.org/10.1042/BJ20140444

Published: 10 July 2014

View articletitled, An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation

Includes: Supplementary data

Articles

The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

Sam Strickson, David G. Campbell, Christoph H. Emmerich, Axel Knebel, Lorna Plater, Maria Stella Ritorto, Natalia Shpiro, Philip Cohen

Biochem J (2013) 451 (3): 427–437.

https://doi.org/10.1042/BJ20121651

Published: 12 April 2013

View articletitled, The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

Includes: Supplementary data

Articles

Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

Eddy T. H. Goh, J. Simon C. Arthur, Peter C. F. Cheung, Shizuo Akira, Rachel Toth, Philip Cohen

Biochem J (2012) 441 (1): 339–346.

https://doi.org/10.1042/BJ20111415

Published: 14 December 2011

View articletitled, Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

Includes: Supplementary data

Articles

The role of TBK1 and IKKϵ in the expression and activation of Pellino 1

Hilary Smith, Xin-Yu Liu, Liang Dai, Eddy T. H. Goh, Aye-Thu Chan, Jiajia Xi, Cheah-Chen Seh, Insaf A. Qureshi, Julien Lescar, Christiane Ruedl, Robert Gourlay, Simon Morton, Joanne Hough, Edward G. McIver, Philip Cohen, Peter C. F. Cheung

Biochem J (2011) 434 (3): 537–548.

https://doi.org/10.1042/BJ20101421

Published: 24 February 2011

View articletitled, The role of TBK1 and IKKϵ in the expression and activation of Pellino 1

Includes: Supplementary data

Articles

Novel cross-talk within the IKK family controls innate immunity

Kristopher Clark, Mark Peggie, Lorna Plater, Ronald J. Sorcek, Erick R. R. Young, Jeffrey B. Madwed, Joanne Hough, Edward G. McIver, Philip Cohen

Biochem J (2011) 434 (1): 93–104.

https://doi.org/10.1042/BJ20101701

Published: 27 January 2011

View articletitled, Novel cross-talk within the IKK family controls innate immunity

Includes: Supplementary data

Articles

Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation

Philip Cohen

Biochem J (2010) 425 (1): 53–54.

https://doi.org/10.1042/BJ20091428

Published: 14 December 2009

View articletitled, Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation

Articles

IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2

Hosea Handoyo, Margaret J. Stafford, Eamon McManus, Dionissios Baltzis, Mark Peggie, Philip Cohen

Biochem J (2009) 424 (1): 109–118.

https://doi.org/10.1042/BJ20091271

Published: 23 October 2009

View articletitled, IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2

Includes: Supplementary data

Articles

Phosphorylation of Ewing's sarcoma protein (EWS) and EWS-Fli1 in response to DNA damage

Iva V. Klevernic, Simon Morton, Roger J. Davis, Philip Cohen

Biochem J (2009) 418 (3): 625–634.

https://doi.org/10.1042/BJ20082097

Published: 25 February 2009

View articletitled, Phosphorylation of Ewing's sarcoma protein (EWS) and EWS-Fli1 in response to DNA damage

Articles

Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology

Mark Windheim, Mark Peggie, Philip Cohen

Biochem J (2008) 409 (3): 723–729.

https://doi.org/10.1042/BJ20071338

Published: 15 January 2008

View articletitled, Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology

Articles

Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex

Heidi Mendoza, David G. Campbell, Kerry Burness, James Hastie, Natalia Ronkina, Jae-Hyuck Shim, J. Simon C. Arthur, Roger J. Davis, Matthias Gaestel, Gary L. Johnson, Sankar Ghosh, Philip Cohen

Biochem J (2008) 409 (3): 711–722.

https://doi.org/10.1042/BJ20071149

Published: 15 January 2008

View articletitled, Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex

Articles

The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys 63 -linked polyubiquitination of IRAK1

Alban Ordureau, Hilary Smith, Mark Windheim, Mark Peggie, Emma Carrick, Nick Morrice, Philip Cohen

Biochem J (2008) 409 (1): 43–52.

https://doi.org/10.1042/BJ20071365

Published: 11 December 2007

View articletitled, The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys 63 -linked polyubiquitination of IRAK1

Articles

The selectivity of protein kinase inhibitors: a further update

Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C. James Hastie, Hilary Mclauchlan, Iva Klevernic, J. Simon C. Arthur, Dario R. Alessi, Philip Cohen

Biochem J (2007) 408 (3): 297–315.

https://doi.org/10.1042/BJ20070797

Published: 28 November 2007

View articletitled, The selectivity of protein kinase inhibitors: a further update

Includes: Supplementary data

Articles

Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

Mark Windheim, Christine Lang, Mark Peggie, Lorna A. Plater, Philip Cohen

Biochem J (2007) 404 (2): 179–190.

https://doi.org/10.1042/BJ20061704

Published: 14 May 2007

View articletitled, Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

Articles

BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

Gopal P. Sapkota, Lorna Cummings, Felicity S. Newell, Christopher Armstrong, Jennifer Bain, Morten Frodin, Matthias Grauert, Matthias Hoffmann, Gisela Schnapp, Martin Steegmaier, Philip Cohen, Dario R. Alessi

Biochem J (2007) 401 (1): 29–38.

https://doi.org/10.1042/BJ20061088

Published: 11 December 2006

View articletitled, BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

Includes: Supplementary data

Articles

TAK1-binding protein 1 is a pseudophosphatase

Sarah H. Conner, Gursant Kular, Mark Peggie, Sharon Shepherd, Alexander W. Schüttelkopf, Philip Cohen, Daan M. F. Van Aalten

Biochem J (2006) 399 (3): 427–434.

https://doi.org/10.1042/BJ20061077

Published: 13 October 2006

View articletitled, TAK1-binding protein 1 is a pseudophosphatase

Articles

Phosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZ

Simon Morton, Huei-Ting Yang, Ntsane Moleleki, David G. Campbell, Philip Cohen, Simon Rousseau

Biochem J (2006) 399 (2): 265–273.

https://doi.org/10.1042/BJ20060681

Published: 27 September 2006

View articletitled, Phosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZ

Articles

Characterization of the reversible phosphorylation and activation of ERK8

Iva V. Klevernic, Margaret J. Stafford, Nicholas Morrice, Mark Peggie, Simon Morton, Philip Cohen

Biochem J (2006) 394 (1): 365–373.

https://doi.org/10.1042/BJ20051288

Published: 27 January 2006

View articletitled, Characterization of the reversible phosphorylation and activation of ERK8

Articles

KESTREL: a powerful method for identifying the physiological substrates of protein kinases

Philip Cohen, Axel Knebel

Biochem J (2006) 393 (1): 1–6.

https://doi.org/10.1042/BJ20051545

Published: 12 December 2005

View articletitled, KESTREL: a powerful method for identifying the physiological substrates of protein kinases

Articles

Nogo-B is a new physiological substrate for MAPKAP-K2

Simon Rousseau, Mark Peggie, David G. Campbell, Angel R. Nebreda, Philip Cohen

Biochem J (2005) 391 (2): 433–440.

https://doi.org/10.1042/BJ20050935

Published: 10 October 2005

View articletitled, Nogo-B is a new physiological substrate for MAPKAP-K2

Articles

Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL

Gillian C. Auld, David G. Campbell, Nick Morrice, Philip Cohen

Biochem J (2005) 389 (3): 775–783.

https://doi.org/10.1042/BJ20050733

Published: 26 July 2005

View articletitled, Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL

Articles

The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ

Claire E. EYERS, Helen McNEILL, Axel KNEBEL, Nick MORRICE, Simon J. C. ARTHUR, Ana CUENDA, Philip COHEN

Biochem J (2005) 389 (1): 127–135.

https://doi.org/10.1042/BJ20050387

Published: 21 June 2005

View articletitled, The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ

Articles

Identification of filamin C as a new physiological substrate of PKBα using KESTREL

James T. MURRAY, David G. CAMPBELL, Mark PEGGIE, Mora ALFONSO, Philip COHEN

Biochem J (2004) 384 (3): 489–494.

https://doi.org/10.1042/BJ20041058

Published: 07 December 2004

View articletitled, Identification of filamin C as a new physiological substrate of PKBα using KESTREL

Articles

Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3

James T. MURRAY, David G. CAMPBELL, Nicholas MORRICE, Gillian C. AULD, Natalia SHPIRO, Rodolpho MARQUEZ, Mark PEGGIE, Jenny BAIN, Graham B. BLOOMBERG, Florian GRAHAMMER, Florian LANG, Peer WULFF, Dietmar KUHL, Philip COHEN

Biochem J (2004) 384 (3): 477–488.

https://doi.org/10.1042/BJ20041057

Published: 07 December 2004

View articletitled, Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3

Articles

A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs

Helen McNEILL, Axel KNEBEL, J. Simon C. ARTHUR, Ana CUENDA, Philip COHEN

Biochem J (2004) 384 (2): 391–400.

https://doi.org/10.1042/BJ20041498

Published: 23 November 2004

View articletitled, A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs

Includes: Supplementary data

Articles

TAB3, a new binding partner of the protein kinase TAK1

Peter C. F. CHEUNG, Angel R. NEBREDA, Philip COHEN

Biochem J (2004) 378 (1): 27–34.

https://doi.org/10.1042/bj20031794

Published: 15 February 2004

View articletitled, TAB3, a new binding partner of the protein kinase TAK1

Articles

Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event

Adam COLE, Sheelagh FRAME, Philip COHEN

Biochem J (2004) 377 (1): 249–255.

https://doi.org/10.1042/bj20031259

Published: 01 January 2004

View articletitled, Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event

Articles

An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro

Nimesh MODY, David G. CAMPBELL, Nick MORRICE, Mark PEGGIE, Philip COHEN

Biochem J (2003) 372 (2): 567–575.

https://doi.org/10.1042/bj20030193

Published: 01 June 2003

View articletitled, An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro

Articles

The specificities of protein kinase inhibitors: an update

Jenny BAIN, Hilary McLAUCHLAN, Matthew ELLIOTT, Philip COHEN

Biochem J (2003) 371 (1): 199–204.

https://doi.org/10.1042/bj20021535

Published: 01 April 2003

View articletitled, The specificities of protein kinase inhibitors: an update

Articles

Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and −insensitive pathways

Axel KNEBEL, Claire E. HAYDON, Nick MORRICE, Philip COHEN

Biochem J (2002) 367 (2): 525–532.

https://doi.org/10.1042/bj20020916

Published: 15 October 2002

View articletitled, Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and −insensitive pathways

Articles

A non-radioactive method for the assay of many serine/threonine-specific protein kinases

Heike ROSS, Christopher G. ARMSTRONG, Philip COHEN

Biochem J (2002) 366 (3): 977–981.

https://doi.org/10.1042/bj20020786

Published: 15 September 2002

View articletitled, A non-radioactive method for the assay of many serine/threonine-specific protein kinases

Articles

GSK3 takes centre stage more than 20 years after its discovery

Sheelagh FRAME, Philip COHEN

Biochem J (2001) 359 (1): 1–16.

https://doi.org/10.1042/bj3590001

Published: 24 September 2001

View articletitled, GSK3 takes centre stage more than 20 years after its discovery

Articles

The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site

Yvonne L. WOODS, Graham RENA, Nick MORRICE, Andreas BARTHEL, Walter BECKER, Shaodong GUO, Terry G. UNTERMAN, Philip COHEN

Biochem J (2001) 355 (3): 597–607.

https://doi.org/10.1042/bj3550597

Published: 24 April 2001

View articletitled, The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site

Articles

The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bɛ at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase

Yvonne L. WOODS, Philip COHEN, Walter BECKER, Ross JAKES, Michel GOEDERT, Xuemin WANG, Christopher G. PROUD

Biochem J (2001) 355 (3): 609–615.

https://doi.org/10.1042/bj3550609

Published: 24 April 2001

View articletitled, The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bɛ at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase

Articles

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Graham RENA, Alan R. PRESCOTT, Shaodong GUO, Philip COHEN, Terry G. UNTERMAN

Biochem J (2001) 354 (3): 605–612.

https://doi.org/10.1042/bj3540605

Published: 08 March 2001

View articletitled, Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Includes: Supplementary data

Articles

Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi

Peter C. F. CHEUNG, Laura TRINKLE-MULCAHY, Philip COHEN, John M. LUCOCQ

Biochem J (2001) 355 (1): 113–121.

https://doi.org/10.1042/bj3550113

Published: 26 February 2001

View articletitled, Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi

Articles

Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

Yvonne FLEMING, Christopher G. ARMSTRONG, Nick MORRICE, Andrew PATERSON, Michel GOEDERT, Philip COHEN

Biochem J (2000) 352 (1): 145–154.

https://doi.org/10.1042/bj3520145

Published: 07 November 2000

View articletitled, Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

Articles

Specificity and mechanism of action of some commonly used protein kinase inhibitors

Stephen P. DAVIES, Helen REDDY, Matilde CAIVANO, Philip COHEN

Biochem J (2000) 351 (1): 95–105.

https://doi.org/10.1042/bj3510095

Published: 26 September 2000

View articletitled, Specificity and mechanism of action of some commonly used protein kinase inhibitors

Articles

Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

Jose M. LIZCANO, Nick MORRICE, Philip COHEN

Biochem J (2000) 349 (2): 547–557.

https://doi.org/10.1042/bj3490547

Published: 10 July 2000

View articletitled, Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

Articles

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

Takayasu KOBAYASHI, Maria DEAK, Nick MORRICE, Philip COHEN

Biochem J (1999) 344 (1): 189–197.

https://doi.org/10.1042/bj3440189

Published: 08 November 1999

View articletitled, Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

Articles

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

Takayasu KOBAYASHI, Philip COHEN

Biochem J (1999) 339 (2): 319–328.

https://doi.org/10.1042/bj3390319

Published: 08 April 1999

View articletitled, Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

Articles

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

Richard A. CURRIE, Kay S. WALKER, Alex GRAY, Maria DEAK, Antonio CASAMAYOR, C. Peter DOWNES, Philip COHEN, Dario R. ALESSI, John LUCOCQ

Biochem J (1999) 337 (3): 575–583.

https://doi.org/10.1042/bj3370575

Published: 25 January 1999

View articletitled, Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

Articles

The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2

Morag SHAW, Philip COHEN, Dario R. ALESSI

Biochem J (1998) 336 (1): 241–246.

https://doi.org/10.1042/bj3360241

Published: 15 November 1998

View articletitled, The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2

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