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R. Elwyn ISAAC
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Articles

Crystal structures of angiotensin-converting enzyme from Anopheles gambiae in its native form and with a bound inhibitor

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John S. Cashman, Gyles E. Cozier, Charlotte Harrison, R. Elwyn Isaac, K. Ravi Acharya
Journal: Biochemical Journal
Biochem J (2019) 476 (22): 3505–3520.
https://doi.org/10.1042/BCJ20190635
Published: 27 November 2019
View articletitled, Crystal structures of angiotensin-converting enzyme from Anopheles gambiae in its native form and with a bound inhibitor
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Articles

Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function

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Josie E. THOMAS, Caroline M. RYLETT, Ahmet CARHAN, Nicholas D. BLAND, Richard J. BINGHAM, Alan D. SHIRRAS, Anthony J. TURNER, R. Elwyn ISAAC
Journal: Biochemical Journal
Biochem J (2005) 386 (2): 357–366.
https://doi.org/10.1042/BJ20041753
Published: 22 February 2005
View articletitled, Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function
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Articles

Ance, a Drosophila angiotensin-converting enzyme homologue, is expressed in imaginal cells during metamorphosis and is regulated by the steroid, 20-hydroxyecdysone

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Richard J. SIVITER, Christine A.M. TAYLOR, Deborah M. COTTAM, Adrian DENTON, M. Paulina DANI, Martin J. MILNER, Alan D. SHIRRAS, R. Elwyn ISAAC
Journal: Biochemical Journal
Biochem J (2002) 367 (1): 187–193.
https://doi.org/10.1042/bj20020567
Published: 01 October 2002
View articletitled, Ance, a Drosophila angiotensin-converting enzyme homologue, is expressed in imaginal cells during metamorphosis and is regulated by the steroid, 20-hydroxyecdysone
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Articles

Rapid purification and characterization of l-dopachrome-methyl ester tautomerase (macrophage-migration-inhibitory factor) from Trichinella spiralis, Trichuris muris and Brugia pahangi

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Joanne L. PENNOCK, Jerzy M. BEHNKE, Quentin D. BICKLE, Eileen DEVANEY, Richard K. GRENCIS, R. Elwyn ISAAC, George W. P. JOSHUA, Murray E. SELKIRK, Yaobi ZHANG, David J. MEYER
Journal: Biochemical Journal
Biochem J (1998) 335 (3): 495–498.
https://doi.org/10.1042/bj3350495
Published: 01 November 1998
View articletitled, Rapid purification and characterization of l-dopachrome-methyl ester tautomerase (macrophage-migration-inhibitory factor) from Trichinella spiralis, Trichuris muris and Brugia pahangi
Open the PDF for Rapid purification and characterization of l-dopachrome-methyl ester tautomerase (macrophage-migration-inhibitory factor) from Trichinella spiralis, Trichuris muris and Brugia pahangi in another window
Articles

A novel peptide-processing activity of insect peptidyl-dipeptidase A (angiotensin I-converting enzyme): the hydrolysis of lysyl-arginine and arginyl-arginine from the C-terminus of an insect prohormone peptide

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R. Elwyn ISAAC, Liliane SCHOOFS, A. Tracy WILLIAMS, Dirk VEELAERT, Mohammed SAJID, Pierre CORVOL, David COATES
Journal: Biochemical Journal
Biochem J (1998) 330 (1): 61–65.
https://doi.org/10.1042/bj3300061
Published: 15 February 1998
View articletitled, A novel peptide-processing activity of insect peptidyl-dipeptidase A (angiotensin I-converting enzyme): the hydrolysis of lysyl-arginine and arginyl-arginine from the C-terminus of an insect prohormone peptide
Open the PDF for A novel peptide-processing activity of insect peptidyl-dipeptidase A (angiotensin I-converting enzyme): the hydrolysis of lysyl-arginine and arginyl-arginine from the C-terminus of an insect prohormone peptide in another window
Articles

Cleavage of arginyl-arginine and lysyl-arginine from the C-terminus ofpro-hormone peptides by human germinal angiotensin I-converting enzyme (ACE) and the C-domain of human somatic ACE

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R. Elwyn ISAAC, A. Tracy WILLIAMS, Mohammed SAJID, Pierre CORVOL, David COATES
Journal: Biochemical Journal
Biochem J (1997) 328 (2): 587–591.
https://doi.org/10.1042/bj3280587
Published: 01 December 1997
View articletitled, Cleavage of arginyl-arginine and lysyl-arginine from the C-terminus ofpro-hormone peptides by human germinal angiotensin I-converting enzyme (ACE) and the C-domain of human somatic ACE
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Articles

The endopeptidase activity and the activation by Cl − of angiotensin-converting enzyme is evolutionarily conserved: purification and properties of an an angiotensin-converting enzyme from the housefly, Musca domestica

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Nazarius S. LAMANGO, Mohammed SAJID, R. Elwyn ISAAC
Journal: Biochemical Journal
Biochem J (1996) 314 (2): 639–646.
https://doi.org/10.1042/bj3140639
Published: 01 March 1996
View articletitled, The endopeptidase activity and the activation by Cl − of angiotensin-converting enzyme is evolutionarily conserved: purification and properties of an an angiotensin-converting enzyme from the housefly, Musca domestica
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Articles

Purification and characterization of prostaglandin-H E-isomerase, a sigma-class glutathione S-transferase, from Ascaridia galli

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David J. MEYER, Richmond MUIMO, Michael THOMAS, David COATES, R. Elwyn ISAAC
Journal: Biochemical Journal
Biochem J (1996) 313 (1): 223–227.
https://doi.org/10.1042/bj3130223
Published: 01 January 1996
View articletitled, Purification and characterization of prostaglandin-H E-isomerase, a sigma-class glutathione S-transferase, from Ascaridia galli
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