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Genetic modulation of CWD prion propagation in cervid PrP Drosophila

Alana M. Thackray, Erin E. McNulty, Amy V. Nalls, Alzbeta Cardova, Linh Tran, Glenn Telling, Sylvie L. Benestad, Sabine Gilch, Candace K. Mathiason, Raymond Bujdoso

Biochem J (2023) 480 (19): 1485–1501.

https://doi.org/10.1042/BCJ20230247

Published: 04 October 2023

View articletitled, Genetic modulation of CWD prion propagation in cervid PrP Drosophila

Articles

Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease

Alana M. Thackray, Brian Lam, Anisa Shahira Binti Ab Razak, Giles Yeo, Raymond Bujdoso

Biochem J (2020) 477 (4): 833–852.

https://doi.org/10.1042/BCJ20190872

Published: 28 February 2020

View articletitled, Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease

Includes: Supplementary data

Articles

Genetic human prion disease modelled in PrP transgenic Drosophila

Alana M. Thackray, Alzbeta Cardova, Hanna Wolf, Lydia Pradl, Ina Vorberg, Walker S. Jackson, Raymond Bujdoso

Biochem J (2017) 474 (19): 3253–3267.

https://doi.org/10.1042/BCJ20170462

Published: 20 September 2017

View articletitled, Genetic human prion disease modelled in PrP transgenic Drosophila

Includes: Supplementary data

Articles

Bioassay of prion-infected blood plasma in PrP transgenic Drosophila

Alana M. Thackray, Olivier Andreoletti, Raymond Bujdoso

Biochem J (2016) 473 (23): 4399–4412.

https://doi.org/10.1042/BCJ20160417

Published: 25 November 2016

View articletitled, Bioassay of prion-infected blood plasma in PrP transgenic Drosophila

Articles

Prion-induced and spontaneous formation of transmissible toxicity in PrP transgenic Drosophila

Alana M. Thackray, Ying Di, Chang Zhang, Hanna Wolf, Lydia Pradl, Ina Vorberg, Olivier Andréoletti, Raymond Bujdoso

Biochem J (2014) 463 (1): 31–40.

https://doi.org/10.1042/BJ20140129

Published: 08 September 2014

View articletitled, Prion-induced and spontaneous formation of transmissible toxicity in PrP transgenic Drosophila

Includes: Supplementary data

Articles

Ovine PrP transgenic Drosophila show reduced locomotor activity and decreased survival

Alana M. Thackray, Farooq Muhammad, Chang Zhang, Ying Di, Thomas R. Jahn, Matthias Landgraf, Damian C. Crowther, Jan Felix Evers, Raymond Bujdoso

Biochem J (2012) 444 (3): 487–495.

https://doi.org/10.1042/BJ20112141

Published: 29 May 2012

View articletitled, Ovine PrP transgenic Drosophila show reduced locomotor activity and decreased survival

Articles

The stability and aggregation of ovine prion protein associated with classical and atypical scrapie correlates with the ease of unwinding of helix-2

Tim J. Fitzmaurice, David F. Burke, Lee Hopkins, Sujeong Yang, Shuiliang Yu, Man-Sun Sy, Alana M. Thackray, Raymond Bujdoso

Biochem J (2008) 409 (2): 367–375.

https://doi.org/10.1042/BJ20071122

Published: 21 December 2007

View articletitled, The stability and aggregation of ovine prion protein associated with classical and atypical scrapie correlates with the ease of unwinding of helix-2

Articles

Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay

Alana M. Thackray, Lee Hopkins, Raymond Bujdoso

Biochem J (2007) 401 (2): 475–483.

https://doi.org/10.1042/BJ20061264

Published: 21 December 2006

View articletitled, Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay

Articles

Ovine plasma prion protein levels show genotypic variation detected by C-terminal epitopes not exposed in cell-surface PrP C

Alana M. Thackray, Tim J. Fitzmaurice, Lee Hopkins, Raymond Bujdoso

Biochem J (2006) 400 (2): 349–358.

https://doi.org/10.1042/BJ20060746

Published: 14 November 2006

View articletitled, Ovine plasma prion protein levels show genotypic variation detected by C-terminal epitopes not exposed in cell-surface PrP C

Articles

Modification of blood cell PrP epitope exposure during prion disease

Alana M. Thackray, Stephen J. Ryder, Raymond Bujdoso

Biochem J (2005) 390 (2): 563–571.

https://doi.org/10.1042/BJ20050571

Published: 23 August 2005

View articletitled, Modification of blood cell PrP epitope exposure during prion disease

Articles

Conformational variation between allelic variants of cell-surface ovine prion protein

Alana M. THACKRAY, Sujeong YANG, Edmond WONG, Tim J. FITZMAURICE, Robert J. MORGAN-WARREN, Raymond BUJDOSO

Biochem J (2004) 381 (1): 221–229.

https://doi.org/10.1042/BJ20040351

Published: 22 June 2004

View articletitled, Conformational variation between allelic variants of cell-surface ovine prion protein

Articles

Copper induces increased beta-sheet content in the scrapie-susceptible ovine prion protein PrPVRQ compared with the resistant allelic variant PrPARR

Edmond WONG, Alana M. THACKRAY, Raymond BUJDOSO

Biochem J (2004) 380 (1): 273–282.

https://doi.org/10.1042/bj20031767

Published: 15 May 2004

View articletitled, Copper induces increased beta-sheet content in the scrapie-susceptible ovine prion protein PrPVRQ compared with the resistant allelic variant PrPARR

Articles

Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein

Alana M. THACKRAY, Jean-Yves MADEC, Edmond WONG, Robert MORGAN-WARREN, David R. BROWN, Thierry BARON, Raymond BUJDOSO

Biochem J (2003) 370 (1): 81–90.

https://doi.org/10.1042/bj20021280

Published: 15 February 2003

View articletitled, Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein

Articles

Metal imbalance and compromised antioxidant function are early changes in prion disease

Alana M. THACKRAY, Robert KNIGHT, Stephen J. HASWELL, Raymond BUJDOSO, David R. BROWN

Biochem J (2002) 362 (2): 253–258.

https://doi.org/10.1042/bj3620253

Published: 22 February 2002

View articletitled, Metal imbalance and compromised antioxidant function are early changes in prion disease

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Genetic modulation of CWD prion propagation in cervid PrP Drosophila

Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease

Genetic human prion disease modelled in PrP transgenic Drosophila

Bioassay of prion-infected blood plasma in PrP transgenic Drosophila

Prion-induced and spontaneous formation of transmissible toxicity in PrP transgenic Drosophila

Ovine PrP transgenic Drosophila show reduced locomotor activity and decreased survival

The stability and aggregation of ovine prion protein associated with classical and atypical scrapie correlates with the ease of unwinding of helix-2

Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay

Ovine plasma prion protein levels show genotypic variation detected by C-terminal epitopes not exposed in cell-surface PrP C

Modification of blood cell PrP epitope exposure during prion disease

Conformational variation between allelic variants of cell-surface ovine prion protein

Copper induces increased beta-sheet content in the scrapie-susceptible ovine prion protein PrPVRQ compared with the resistant allelic variant PrPARR

Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein

Metal imbalance and compromised antioxidant function are early changes in prion disease

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