1-21 of 21
Robin F. Irvine
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases α and β are dynamic and independently regulated during starvation-induced stress

Alaa Droubi, Simon J. Bulley, Jonathan H. Clarke, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2016) 473 (14): 2155–2163.
https://doi.org/10.1042/BCJ20160380
Published: 12 July 2016
View articletitled, Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases α and β are dynamic and independently regulated during starvation-induced stress
Open the PDF for Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases α and β are dynamic and independently regulated during starvation-induced stress in another window
Includes: Supplementary data
Articles

The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site

Jonathan H. Clarke, Maria-Luisa Giudici, John E. Burke, Roger L. Williams, David J. Maloney, Juan Marugan, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2015) 466 (2): 359–367.
https://doi.org/10.1042/BJ20141333
Published: 20 February 2015
View articletitled, The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site
Open the PDF for The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site in another window
Includes: Supplementary data
Articles

Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

Jonathan H. Clarke, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2013) 454 (1): 49–57.
https://doi.org/10.1042/BJ20130488
Published: 26 July 2013
View articletitled, Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization
Open the PDF for Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization in another window
Includes: Supplementary data
Articles

Genomic tagging reveals a random association of endogenous PtdIns5 P 4-kinases IIα and IIβ and a partial nuclear localization of the IIα isoform

Minchuan Wang, Nicholas J. Bond, Andrew J. Letcher, Jonathan P. Richardson, Kathryn S. Lilley, Robin F. Irvine, Jonathan H. Clarke
Journal: Biochemical Journal
Biochem J (2010) 430 (2): 215–221.
https://doi.org/10.1042/BJ20100340
Published: 13 August 2010
View articletitled, Genomic tagging reveals a random association of endogenous PtdIns5 P 4-kinases IIα and IIβ and a partial nuclear localization of the IIα isoform
Open the PDF for Genomic tagging reveals a random association of endogenous PtdIns5 P 4-kinases IIα and IIβ and a partial nuclear localization of the IIα isoform in another window
Includes: Supplementary data
Articles

Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4 P and PtdIns(4,5) P 2

Gerald R. V. Hammond, Giampietro Schiavo, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2009) 422 (1): 23–35.
https://doi.org/10.1042/BJ20090428
Published: 29 July 2009
View articletitled, Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4 P and PtdIns(4,5) P 2
Open the PDF for Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4 P and PtdIns(4,5) P 2 in another window
Includes: Multimedia, Supplementary data
Articles

Do mammals make all their own inositol hexakisphosphate?

Andrew J. Letcher, Michael J. Schell, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2008) 416 (2): 263–270.
https://doi.org/10.1042/BJ20081417
Published: 12 November 2008
View articletitled, Do mammals make all their own inositol hexakisphosphate?
Open the PDF for Do mammals make all their own inositol hexakisphosphate? in another window
Articles

Regulation of the localization and activity of inositol 1,4,5-trisphosphate 3-kinase B in intact cells by proteolysis

Jowie C. H. Yu, Samantha M. Lloyd-Burton, Robin F. Irvine, Michael J. Schell
Journal: Biochemical Journal
Biochem J (2005) 392 (3): 435–441.
https://doi.org/10.1042/BJ20050829
Published: 06 December 2005
View articletitled, Regulation of the localization and activity of inositol 1,4,5-trisphosphate 3-kinase B in intact cells by proteolysis
Open the PDF for Regulation of the localization and activity of inositol 1,4,5-trisphosphate 3-kinase B in intact cells by proteolysis in another window
Articles

Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility

David Brough, Michael J. Schell, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2005) 392 (2): 291–297.
https://doi.org/10.1042/BJ20050738
Published: 22 November 2005
View articletitled, Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility
Open the PDF for Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility in another window
Articles

A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma

Maria-Luisa GIUDICI, Piers C. EMSON, Robin F. IRVINE
Journal: Biochemical Journal
Biochem J (2004) 379 (2): 489–496.
https://doi.org/10.1042/bj20031394
Published: 15 April 2004
View articletitled, A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma
Open the PDF for A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma in another window
Articles

Kinetic model of the inositol trisphosphate receptor that shows both steady-state and quantal patterns of Ca2+ release from intracellular stores

Alan P. DAWSON, Edward J.A. LEA, Robin F. IRVINE
Journal: Biochemical Journal
Biochem J (2003) 370 (2): 621–629.
https://doi.org/10.1042/bj20021289
Published: 01 March 2003
View articletitled, Kinetic model of the inositol trisphosphate receptor that shows both steady-state and quantal patterns of Ca2+ release from intracellular stores
Open the PDF for Kinetic model of the inositol trisphosphate receptor that shows both steady-state and quantal patterns of Ca2+ release from intracellular stores in another window
Articles

Type IIα phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms

Katherine A. HINCHLIFFE, Maria Luisa GIUDICI, Andrew J. LETCHER, Robin F. IRVINE
Journal: Biochemical Journal
Biochem J (2002) 363 (3): 563–570.
https://doi.org/10.1042/bj3630563
Published: 24 April 2002
View articletitled, Type IIα phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms
Open the PDF for Type IIα phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms in another window
Articles

Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells

Jonathan H. CLARKE, Andrew J. LETCHER, Clive S. D'SANTOS, Jonathan R. HALSTEAD, Robin F. IRVINE, Nullin DIVECHA
Journal: Biochemical Journal
Biochem J (2001) 357 (3): 905–910.
https://doi.org/10.1042/bj3570905
Published: 25 July 2001
View articletitled, Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells
Open the PDF for Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells in another window
Articles

The effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-induced Ca2+ mobilization in freshly isolated and cultured mouse lacrimal acinar cells

Peter M. SMITH, Alexander R. HARMER, Andrew J. LETCHER, Robin F. IRVINE
Journal: Biochemical Journal
Biochem J (2000) 347 (1): 77–82.
https://doi.org/10.1042/bj3470077
Published: 27 March 2000
View articletitled, The effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-induced Ca2+ mobilization in freshly isolated and cultured mouse lacrimal acinar cells
Open the PDF for The effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-induced Ca2+ mobilization in freshly isolated and cultured mouse lacrimal acinar cells in another window
Articles

Nuclear targeting of the β isoform of Type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its α-helix 7

Antonio CIRUELA, Katherine A. HINCHLIFFE, Nullin DIVECHA, Robin F. IRVINE
Journal: Biochemical Journal
Biochem J (2000) 346 (3): 587–591.
https://doi.org/10.1042/bj3460587
Published: 07 March 2000
View articletitled, Nuclear targeting of the β isoform of Type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its α-helix 7
Open the PDF for Nuclear targeting of the β isoform of Type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its α-helix 7 in another window
Articles

Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by Ins(1,3,4,5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor

Jefferson W. LOOMIS-HUSSELBEE, Christopher D. WALKER, Joanna R. BOTTOMLEY, Peter J. CULLEN, Robin F. IRVINE, Alan P. DAWSON
Journal: Biochemical Journal
Biochem J (1998) 331 (3): 947–952.
https://doi.org/10.1042/bj3310947
Published: 01 May 1998
View articletitled, Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by Ins(1,3,4,5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor
Open the PDF for Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by Ins(1,3,4,5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor in another window
Articles

Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors

Jonathan S. MARCHANT, Young-Tae CHANG, Sung-Kee CHUNG, Robin F. IRVINE, Colin W. TAYLOR
Journal: Biochemical Journal
Biochem J (1997) 321 (3): 573–576.
https://doi.org/10.1042/bj3210573
Published: 01 February 1997
View articletitled, Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors
Open the PDF for Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors in another window
Articles

Synergistic effects of inositol 1,3,4,5-tetrakisphosphate on inositol 2,4,5-triphosphate-stimulated Ca 2+ release do not involve direct interaction of inositol 1,3,4,5-tetrakisphosphate with inositol triphosphate-binding sites

Jeff W. LOOMIS-HUSSELBEE, Peter J. CULLEN, Uschi E. DREIKHAUSEN, Robin F. IRVINE, Alan P. DAWSON
Journal: Biochemical Journal
Biochem J (1996) 314 (3): 811–816.
https://doi.org/10.1042/bj3140811
Published: 15 March 1996
View articletitled, Synergistic effects of inositol 1,3,4,5-tetrakisphosphate on inositol 2,4,5-triphosphate-stimulated Ca 2+ release do not involve direct interaction of inositol 1,3,4,5-tetrakisphosphate with inositol triphosphate-binding sites
Open the PDF for Synergistic effects of inositol 1,3,4,5-tetrakisphosphate on inositol 2,4,5-triphosphate-stimulated Ca 2+ release do not involve direct interaction of inositol 1,3,4,5-tetrakisphosphate with inositol triphosphate-binding sites in another window
Articles

Proteolytic activation can produce a phosphatidylinositol phosphodiesterase highly sensitive to Ca 2+

Keisuke Hirasawa, Robin F. Irvine, Rex M. C. Dawson
Journal: Biochemical Journal
Biochem J (1982) 206 (3): 675–678.
https://doi.org/10.1042/bj2060675
Published: 15 September 1982
View articletitled, Proteolytic activation can produce a phosphatidylinositol phosphodiesterase highly sensitive to Ca 2+
Open the PDF for Proteolytic activation can produce a phosphatidylinositol phosphodiesterase highly sensitive to Ca 2+ in another window
Articles

Heterogeneity of the calcium-dependent phosphatidylinositol phosphodiesterase in rat brain

Keisuke Hirasawa, Robin F. Irvine, Rex M. C. Dawson
Journal: Biochemical Journal
Biochem J (1982) 205 (2): 437–442.
https://doi.org/10.1042/bj2050437
Published: 01 August 1982
View articletitled, Heterogeneity of the calcium-dependent phosphatidylinositol phosphodiesterase in rat brain
Open the PDF for Heterogeneity of the calcium-dependent phosphatidylinositol phosphodiesterase in rat brain in another window
Articles

Hydrolysis of membrane phospholipids by phospholipases of rat liver lysosomes

Donald E. Richards, Robin F. Irvine, Rex M. C. Dawson
Journal: Biochemical Journal
Biochem J (1979) 182 (2): 599–606.
https://doi.org/10.1042/bj1820599
Published: 15 August 1979
View articletitled, Hydrolysis of membrane phospholipids by phospholipases of rat liver lysosomes
Open the PDF for Hydrolysis of membrane phospholipids by phospholipases of rat liver lysosomes in another window
Articles

The effect of ethylene on [1- 14 C]glycerol incorporation into phospholipids of etiolated pea stems

Robin F. Irvine, Daphne J. Osborne
Journal: Biochemical Journal
Biochem J (1973) 136 (4): 1133–1135.
https://doi.org/10.1042/bj1361133
Published: 01 December 1973
View articletitled, The effect of ethylene on [1- 14 C]glycerol incorporation into phospholipids of etiolated pea stems
Open the PDF for The effect of ethylene on [1- 14 C]glycerol incorporation into phospholipids of etiolated pea stems in another window