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Victoria H Cowling
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Articles

Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach

Lesley-Anne Pearson, Alain-Pierre Petit, Cesar Mendoza Martinez, Fiona Bellany, De Lin, Sarah Niven, Rachel Swift, Thomas Eadsforth, Paul Fyfe, Marilyn Paul, Vincent Postis, Xiao Hu, Victoria H. Cowling, David W. Gray
Journal: Biochemical Journal
Biochem J (2025) 482 (04): 209–224.
https://doi.org/10.1042/BCJ20240608
Published: 17 February 2025
View article titled, Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach
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Includes: Supplementary data
Articles

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase

In Collection
Coronavirus , Tackling SARS-CoV-2 biochemistry
Souradeep Basu, Tiffany Mak, Rachel Ulferts, Mary Wu, Tom Deegan, Ryo Fujisawa, Kang Wei Tan, Chew Theng Lim, Clovis Basier, Berta Canal, Joseph F. Curran, Lucy S. Drury, Allison W. McClure, Emma L. Roberts, Florian Weissmann, Theresa U. Zeisner, Rupert Beale, Victoria H. Cowling, Michael Howell, Karim Labib, John F.X. Diffley
Journal: Biochemical Journal
Biochem J (2021) 478 (13): 2481–2497.
https://doi.org/10.1042/BCJ20210219
Published: 02 July 2021
View article titled, Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase
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Includes: Supplementary data
Articles

c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

Sianadh Dunn, Olivia Lombardi, Victoria H. Cowling
Journal: Biochemical Journal
Biochem J (2017) 474 (3): 377–384.
https://doi.org/10.1042/BCJ20160930
Published: 20 January 2017
View article titled, c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production
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Articles

RAM function is dependent on Kapβ2-mediated nuclear entry

Thomas Gonatopoulos-Pournatzis, Victoria H. Cowling
Journal: Biochemical Journal
Biochem J (2014) 457 (3): 473–484.
https://doi.org/10.1042/BJ20131359
Published: 10 January 2014
View article titled, RAM function is dependent on Kapβ2-mediated nuclear entry
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Includes: Supplementary data
Articles

Cap-binding complex (CBC)

Thomas Gonatopoulos-Pournatzis, Victoria H. Cowling
Journal: Biochemical Journal
Biochem J (2014) 457 (2): 231–242.
https://doi.org/10.1042/BJ20131214
Published: 20 December 2013
View article titled, Cap-binding complex (CBC)
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Articles

Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites

Michael Aregger, Victoria H. Cowling
Journal: Biochemical Journal
Biochem J (2013) 455 (1): 67–73.
https://doi.org/10.1042/BJ20130378
Published: 13 September 2013
View article titled, Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites
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Articles

Regulation of mRNA cap methylation

Victoria H. Cowling
Journal: Biochemical Journal
Biochem J (2010) 425 (2): 295–302.
https://doi.org/10.1042/BJ20091352
Published: 23 December 2009
View article titled, Regulation of mRNA cap methylation
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