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Articles

Activity-based probes for dynamic characterisation of polysaccharide-degrading enzymes

Open Access
In Collection
Awards
Isabelle B. Pickles, Thamy L.R. Corrêa, Herman S. Overkleeft, Gideon J. Davies
Journal: Biochemical Journal
Biochem J (2025) 482 (13): 939–954.
https://doi.org/10.1042/BCJ20253060
Published: 01 July 2025
View article titled, Activity-based probes for dynamic characterisation of polysaccharide-degrading enzymes
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Articles

Cas11 augments Cascade functions in type I-E CRISPR system but is redundant for gene silencing and plasmid interference

Open Access
Neha Pandey, Chitra Seetharam Misra, Devashish Rath
Journal: Biochemical Journal
Biochem J (2025) 482 (12): 793–805.
https://doi.org/10.1042/BCJ20253056
Published: 11 June 2025
View article titled, Cas11 augments Cascade functions in type I-E CRISPR system but is redundant for gene silencing and plasmid interference
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Includes: Supplementary data
Articles

Structural and kinetic characterization of an acetoacetyl-Coenzyme A: acetate Coenzyme A transferase from the extreme thermophile Thermosipho melanesiensis

Open Access
Ryan G. Bing, Greg K. Buhrman, Kathryne C. Ford, Christopher T. Straub, Tunyaboon Laemthong, Robert B. Rose, Michael W.W. Adams, Robert M. Kelly
Journal: Biochemical Journal
Biochem J (2025) 482 (04): 225–240.
https://doi.org/10.1042/BCJ20240747
Published: 18 February 2025
View article titled, Structural and kinetic characterization of an acetoacetyl-Coenzyme A: acetate Coenzyme A transferase from the extreme thermophile Thermosipho melanesiensis
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Includes: Supplementary data
Articles

In silico , in vitro, and in vivo characterization of thiamin-binding proteins from plant seeds

Open Access
Maria Faustino, Simon Strobbe, Raul Sanchez-Muñoz, Da Cao, Ratnesh C. Mishra, Tiago Lourenço, M. Margarida Oliveira, Dominique Van Der Straeten
Journal: Biochemical Journal
Biochem J (2025) 482 (04): 181–195.
https://doi.org/10.1042/BCJ20240429
Published: 05 February 2025
View article titled, In silico , in vitro, and in vivo characterization of thiamin-binding proteins from plant seeds
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Includes: Supplementary data
Articles

Nucleic acid joining enzymes: biological functions and synthetic applications beyond DNA

Open Access
Chelsea Blackstock, Caitlin Walters-Freke, Nigel Richards, Adele Williamson
Journal: Biochemical Journal
Biochem J (2025) 482 (2): 39–56.
https://doi.org/10.1042/BCJ20240136
Published: 21 January 2025
View article titled, Nucleic acid joining enzymes: biological functions and synthetic applications beyond DNA
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Includes: Supplementary data
Articles

Ubiquitin E3 ligases in the plant Arg/N-degron pathway

Open Access
Keely E. A. Oldham, Peter D. Mabbitt
Journal: Biochemical Journal
Biochem J (2024) 481 (24): 1949–1965.
https://doi.org/10.1042/BCJ20240132
Published: 13 December 2024
View article titled, Ubiquitin E3 ligases in the plant Arg/N-degron pathway
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Includes: Supplementary data
Articles

A prescription for engineering PFAS biodegradation

Open Access
Lawrence P. Wackett, Serina L. Robinson
Journal: Biochemical Journal
Biochem J (2024) 481 (23): 1757–1770.
https://doi.org/10.1042/BCJ20240283
Published: 25 November 2024
View article titled, A prescription for engineering PFAS biodegradation
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Articles

Comparative analysis of canine and human HtrA2 to delineate its role in apoptosis and cancer

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Snehal P. Mudrale, Shubhankar Dutta, Kalyani Natu, Pradip Chaudhari, Kakoli Bose
Journal: Biochemical Journal
Biochem J (2024) 481 (22): 1603–1620.
https://doi.org/10.1042/BCJ20240295
Published: 07 November 2024
View article titled, Comparative analysis of canine and human HtrA2 to delineate its role in apoptosis and cancer
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Includes: Supplementary data
Articles

Identification of inhibitors of human ChaC1, a cytoplasmic glutathione degrading enzyme through high throughput screens in yeast

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Shradha Suyal, Chinmayee Choudhury, Deepinder Kaur, Anand K. Bachhawat
Journal: Biochemical Journal
Biochem J (2024) 481 (20): 1475–1495.
https://doi.org/10.1042/BCJ20240447
Published: 14 October 2024
View article titled, Identification of inhibitors of human ChaC1, a cytoplasmic glutathione degrading enzyme through high throughput screens in yeast
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Includes: Supplementary data
Articles

Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli

Open Access
In Collection
Coronavirus
Emma L. Brudenell, Manoj B. Pohare, Domen Zafred, Janine Phipps, Hailey R. Hornsby, John F. Darby, Junxiao Dai, Ellen Liggett, Kathleen M. Cain, Perdita E. Barran, Thushan I. de Silva, Jon R. Sayers
Journal: Biochemical Journal
Biochem J (2024) 481 (11): 669–682.
https://doi.org/10.1042/BCJ20240019
Published: 24 May 2024
View article titled, Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli
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Includes: Supplementary data
Articles

Leukotriene B4 receptor 1 does not mediate disease progression in a mouse model of liver fibrosis

Open Access
Erin S. Coyne, Yilin Nie, Desiree Abdurrachim, Charlene Zhi Lin Ong, Yongqi Zhou, Asad Abu Bakar Ali, Stacey Meyers, Jeff Grein, Wendy Blumenschein, Brendan Gongol, Yang Liu, Cedric Hugelshofer, Ester Carballo-Jane, Saswata Talukdar
Journal: Biochemical Journal
Biochem J (2024) 481 (3): 177–190.
https://doi.org/10.1042/BCJ20230422
Published: 05 February 2024
View article titled, Leukotriene B4 receptor 1 does not mediate disease progression in a mouse model of liver fibrosis
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Includes: Supplementary data
Articles

Pseudouridylation-mediated gene expression modulation

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Jonathan L. Chen, W.-Matthias Leeder, Pedro Morais, Hironori Adachi, Yi-Tao Yu
Journal: Biochemical Journal
Biochem J (2024) 481 (1): 1–16.
https://doi.org/10.1042/BCJ20230096
Published: 04 January 2024
View article titled, Pseudouridylation-mediated gene expression modulation
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Articles

Engineering of CYP82Y1, a cytochrome P450 monooxygenase: a key enzyme in noscapine biosynthesis in opium poppy

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Zahra Aghaali, Mohammad Reza Naghavi
Journal: Biochemical Journal
Biochem J (2023) 480 (23): 2009–2022.
https://doi.org/10.1042/BCJ20230243
Published: 08 December 2023
View article titled, Engineering of CYP82Y1, a cytochrome P450 monooxygenase: a key enzyme in noscapine biosynthesis in opium poppy
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Articles

Plant adaptation to climate change

Open Access
In Collection
Plants and climate change: the role of plants in achieving net zero
Christine H. Foyer, Ilse Kranner
Journal: Biochemical Journal
Biochem J (2023) 480 (22): 1865–1869.
https://doi.org/10.1042/BCJ20220580
Published: 23 November 2023
View article titled, Plant adaptation to climate change
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Articles

In search for structural targets for engineering d-amino acid transaminase: modulation of pH optimum and substrate specificity

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Sofia A. Shilova, Ilya O. Matyuta, Maria G. Khrenova, Alena Y. Nikolaeva, Natalia L. Klyachko, Mikhail E. Minyaev, Alex R. Khomutov, Konstantin M. Boyko, Vladimir O. Popov, Ekaterina Yu. Bezsudnova
Journal: Biochemical Journal
Biochem J (2023) 480 (16): 1267–1284.
https://doi.org/10.1042/BCJ20230233
Published: 23 August 2023
View article titled, In search for structural targets for engineering d-amino acid transaminase: modulation of pH optimum and substrate specificity
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Includes: Supplementary data
Articles

Computational design of Matrix Metalloproteinase-9 (MMP-9) resistant to auto-cleavage

Open Access
Alessandro Bonadio, Solomon Oguche, Tali Lavy, Oded Kleifeld, Julia Shifman
Journal: Biochemical Journal
Biochem J (2023) 480 (14): 1097–1107.
https://doi.org/10.1042/BCJ20230139
Published: 17 July 2023
View article titled, Computational design of Matrix Metalloproteinase-9 (MMP-9) resistant to auto-cleavage
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Includes: Supplementary data
Articles

Calcium signalling components underlying NPK homeostasis: potential avenues for exploration

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In Collection
Plants and climate change: the role of plants in achieving net zero
Sonam Pahuja, Malathi Bheri, Diksha Bisht, Girdhar K. Pandey
Journal: Biochemical Journal
Biochem J (2023) 480 (13): 1015–1034.
https://doi.org/10.1042/BCJ20230156
Published: 07 July 2023
View article titled, Calcium signalling components underlying NPK homeostasis: potential avenues for exploration
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Articles

A curated list of targeted optimized promiscuous ketoreductases (TOP-K)

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Anirudh P. Shanbhag, Sreenath Rajagopal, Arindam Ghatak, Nainesh Katagihallimath, Ramaswamy Subramanian, Santanu Datta
Journal: Biochemical Journal
Biochem J (2023) 480 (13): 975–997.
https://doi.org/10.1042/BCJ20230051
Published: 06 July 2023
View article titled, A curated list of targeted optimized promiscuous ketoreductases (TOP-K)
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Includes: Supplementary data
Articles

Unlocking the secrets of the microbiome: exploring the dynamic microbial interplay with humans through metabolomics and their manipulation for synthetic biology applications

Open Access
In Collection
Towards systems biochemistry
Howbeer Muhamadali, Catherine L. Winder, Warwick B. Dunn, Royston Goodacre
Journal: Biochemical Journal
Biochem J (2023) 480 (12): 891–908.
https://doi.org/10.1042/BCJ20210534
Published: 28 June 2023
View article titled, Unlocking the secrets of the microbiome: exploring the dynamic microbial interplay with humans through metabolomics and their manipulation for synthetic biology applications
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Articles

The biology and type I/III hybrid nature of type I-D CRISPR–Cas systems

Open Access
Tess M. McBride, Shaharn C. Cameron, Peter C. Fineran, Robert D. Fagerlund
Journal: Biochemical Journal
Biochem J (2023) 480 (7): 471–488.
https://doi.org/10.1042/BCJ20220073
Published: 13 April 2023
View article titled, The biology and type I/III hybrid nature of type I-D CRISPR–Cas systems
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Includes: Supplementary data
Articles

Identification and characterization of the Doublesex gene and its mRNA isoforms in the brine shrimp Artemia franciscana

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Wen-Tao Wu, Lian-Ying Xu, Zhi-Jun Yan, Ning Bi, Cai-Yuan Cheng, Fan Yang, Wei-Jun Yang, Jin-Shu Yang
Journal: Biochemical Journal
Biochem J (2023) 480 (5): 385–401.
https://doi.org/10.1042/BCJ20220495
Published: 15 March 2023
View article titled, Identification and characterization of the Doublesex gene and its mRNA isoforms in the brine shrimp Artemia franciscana
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Includes: Supplementary data
Articles

From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics

Open Access
In Collection
Cell signaling in the 21st century
Donald E. Ingber
Journal: Biochemical Journal
Biochem J (2023) 480 (4): 243–257.
https://doi.org/10.1042/BCJ20220303
Published: 23 February 2023
View article titled, From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics
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Articles

Impact of climate perturbations on seeds and seed quality for global agriculture

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In Collection
Plants and climate change: the role of plants in achieving net zero
Christophe Bailly, Maria Victoria Gomez Roldan
Journal: Biochemical Journal
Biochem J (2023) 480 (3): 177–196.
https://doi.org/10.1042/BCJ20220246
Published: 07 February 2023
View article titled, Impact of climate perturbations on seeds and seed quality for global agriculture
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Articles

Synthesis, biochemical characterization and in silico investigation of 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid derivatives: dual action mode inhibitors of urease and virulent bacterial stains

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Sajid Irshad, Saeed Ahmad, Shafi Ullah Khan, Mohsin Abbas Khan, Syeda Abida Ejaz, Huma Rao, Umair Khurshid, Aftab Ahmed, Nadeem Shahzad, Hamad M. Al-kahtani, Affan Waheed, Tanveer A. Wani, Abdullahi Tunde Aborode
Journal: Biochemical Journal
Biochem J (2022) 479 (19): 2035–2048.
https://doi.org/10.1042/BCJ20220395
Published: 07 October 2022
View article titled, Synthesis, biochemical characterization and in silico investigation of 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid derivatives: dual action mode inhibitors of urease and virulent bacterial stains
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Articles

Proteomic mapping and optogenetic manipulation of membrane contact sites

Open Access
Gang Lin, Wenyi Shi, Ningxia Zhang, Yi-Tsang Lee, Youjun Wang, Ji Jing
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1857–1875.
https://doi.org/10.1042/BCJ20220382
Published: 16 September 2022
View article titled, Proteomic mapping and optogenetic manipulation of membrane contact sites
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Articles

Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia

Open Access
Marianne J. Satur, Paulina A. Urbanowicz, Daniel I. R. Spencer, John Rafferty, Graham P. Stafford
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1785–1806.
https://doi.org/10.1042/BCJ20220244
Published: 06 September 2022
View article titled, Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia
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Includes: Supplementary data
Articles

The mitochondrial translocator protein (TSPO): a key multifunctional molecule in the nervous system

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Léa El Chemali, Yvette Akwa, Liliane Massaad-Massade
Journal: Biochemical Journal
Biochem J (2022) 479 (13): 1455–1466.
https://doi.org/10.1042/BCJ20220050
Published: 12 July 2022
View article titled, The mitochondrial translocator protein (TSPO): a key multifunctional molecule in the nervous system
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Articles

Improved furfural tolerance in Escherichia coli mediated by heterologous NADH-dependent benzyl alcohol dehydrogenases

Open Access
Benjamin James Willson, Reyme Herman, Swen Langer, Gavin Hugh Thomas
Journal: Biochemical Journal
Biochem J (2022) 479 (10): 1045–1058.
https://doi.org/10.1042/BCJ20210811
Published: 23 May 2022
View article titled, Improved furfural tolerance in Escherichia coli mediated by heterologous NADH-dependent benzyl alcohol dehydrogenases
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Includes: Supplementary data
Articles

The structure and function of modular Escherichia coli O157:H7 bacteriophage FTBEc1 endolysin, LysT84: defining a new endolysin catalytic subfamily

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Michael J. Love, David Coombes, Salim Ismail, Craig Billington, Renwick C. J. Dobson
Journal: Biochemical Journal
Biochem J (2022) 479 (2): 207–223.
https://doi.org/10.1042/BCJ20210701
Published: 28 January 2022
View article titled, The structure and function of modular Escherichia coli O157:H7 bacteriophage FTBEc1 endolysin, LysT84: defining a new endolysin catalytic subfamily
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Includes: Supplementary data
Articles

Making protons tag along with electrons

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Matthew J. Guberman-Pfeffer, Nikhil S. Malvankar
Journal: Biochemical Journal
Biochem J (2021) 478 (23): 4093–4097.
https://doi.org/10.1042/BCJ20210592
Published: 06 December 2021
View article titled, Making protons tag along with electrons
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Articles

Intelligent host engineering for metabolic flux optimisation in biotechnology

Open Access
In Collection
Towards systems biochemistry
Lachlan J. Munro, Douglas B. Kell
Journal: Biochemical Journal
Biochem J (2021) 478 (20): 3685–3721.
https://doi.org/10.1042/BCJ20210535
Published: 21 October 2021
View article titled, Intelligent host engineering for metabolic flux optimisation in biotechnology
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Articles

C -type cytochrome-initiated reduction of bacterial lytic polysaccharide monooxygenases

Open Access
Jessie Branch, Badri S. Rajagopal, Alessandro Paradisi, Nick Yates, Peter J. Lindley, Jake Smith, Kristian Hollingsworth, W. Bruce Turnbull, Bernard Henrissat, Alison Parkin, Alan Berry, Glyn R. Hemsworth
Journal: Biochemical Journal
Biochem J (2021) 478 (14): 2927–2944.
https://doi.org/10.1042/BCJ20210376
Published: 28 July 2021
View article titled, C -type cytochrome-initiated reduction of bacterial lytic polysaccharide monooxygenases
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Includes: Supplementary data
Articles

Translational regulation in pathogenic and beneficial plant–microbe interactions

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Soledad Traubenik, Milagros Ferrari, Flavio Antonio Blanco, María Eugenia Zanetti
Journal: Biochemical Journal
Biochem J (2021) 478 (14): 2775–2788.
https://doi.org/10.1042/BCJ20210066
Published: 23 July 2021
View article titled, Translational regulation in pathogenic and beneficial plant–microbe interactions
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Articles

Hetero-oligomerization of Bacillus thuringiensis Cry1A proteins enhance binding to the ABCC2 transporter of Spodoptera exigua

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Daniel Pinos, Noelia Joya, Salvador Herrero, Juan Ferré, Patricia Hernández-Martínez
Journal: Biochemical Journal
Biochem J (2021) 478 (13): 2589–2600.
https://doi.org/10.1042/BCJ20210137
Published: 09 July 2021
View article titled, Hetero-oligomerization of Bacillus thuringiensis Cry1A proteins enhance binding to the ABCC2 transporter of Spodoptera exigua
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Includes: Supplementary data
Articles

Internalization and membrane activity of the antimicrobial peptide CGA-N12

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Ruifang Li, Mengke Tao, Shang Li, Xueqin Wang, Yanhui Yang, Lianfeng Mo, Kaidi Zhang, Ao Wei, Liang Huang
Journal: Biochemical Journal
Biochem J (2021) 478 (10): 1907–1919.
https://doi.org/10.1042/BCJ20201006
Published: 24 May 2021
View article titled, Internalization and membrane activity of the antimicrobial peptide CGA-N12
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Articles

Glycoengineering: scratching the surface

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Meg Critcher, Timothy O'Leary, Mia L. Huang
Journal: Biochemical Journal
Biochem J (2021) 478 (4): 703–719.
https://doi.org/10.1042/BCJ20200612
Published: 18 February 2021
View article titled, Glycoengineering: scratching the surface
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Articles

Loss of cell wall integrity genes cpxA and mrcB causes flocculation in Escherichia coli

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Keita Sugawara, Hayato Toyoda, Mami Kimura, Shunsuke Hayasaka, Hiromi Saito, Hiroshi Kobayashi, Kunio Ihara, Tomoaki Ida, Takaaki Akaike, Eiji Ando, Mamoru Hyodo, Yoshihiro Hayakawa, Shin Hamamoto, Nobuyuki Uozumi
Journal: Biochemical Journal
Biochem J (2021) 478 (1): 41–59.
https://doi.org/10.1042/BCJ20200723
Published: 08 January 2021
View article titled, Loss of cell wall integrity genes cpxA and mrcB causes flocculation in Escherichia coli
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Articles

Amyloid-beta oligomers induce Parkin-mediated mitophagy by reducing Miro1

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Min Kyoung Kam, Dong Gil Lee, Bokyung Kim, Jae-Won Huh, Hong Jun Lee, Young-Ho Park, Dong-Seok Lee
Journal: Biochemical Journal
Biochem J (2020) 477 (23): 4581–4597.
https://doi.org/10.1042/BCJ20200488
Published: 08 December 2020
View article titled, Amyloid-beta oligomers induce Parkin-mediated mitophagy by reducing Miro1
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Includes: Supplementary data
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Crystal structure of Leptospira leucine-rich repeat 20 reveals a novel E-cadherin binding protein to induce NGAL expression in HK2 cells

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Shen-Hsing Hsu, Chen-Hsi Chu, Ya-Chung Tian, Ming-Yang Chang, Li-Feng Chou, Yuh-Ju Sun, Chih-Wei Yang
Journal: Biochemical Journal
Biochem J (2020) 477 (21): 4313–4326.
https://doi.org/10.1042/BCJ20200547
Published: 13 November 2020
View article titled, Crystal structure of Leptospira leucine-rich repeat 20 reveals a novel E-cadherin binding protein to induce NGAL expression in HK2 cells
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Articles

A structure model explaining the binding between a ubiquitous unconventional G-protein (OsYchF1) and a plant-specific C2-domain protein (OsGAP1) from rice

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Ming-Yan Cheung, Jacky Chi-Ki Ngo, Zhongzhou Chen, Qi Jia, Tianjie Li, Yitao Gou, Yi Wang, Hon-Ming Lam
Journal: Biochemical Journal
Biochem J (2020) 477 (20): 3935–3949.
https://doi.org/10.1042/BCJ20200380
Published: 23 October 2020
View article titled, A structure model explaining the binding between a ubiquitous unconventional G-protein (OsYchF1) and a plant-specific C2-domain protein (OsGAP1) from rice
Open the PDF for A structure model explaining the binding between a ubiquitous unconventional G-protein (OsYchF1) and a plant-specific C2-domain protein (OsGAP1) from rice in another window
Includes: Supplementary data
Articles

Effect of NH 2 -terminal acetylation on the oxygenation properties of vertebrate haemoglobin

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Chandrasekhar Natarajan, Anthony V. Signore, Vikas Kumar, Roy E. Weber, Angela Fago, Jay F. Storz
Journal: Biochemical Journal
Biochem J (2020) 477 (19): 3839–3850.
https://doi.org/10.1042/BCJ20200623
Published: 12 October 2020
View article titled, Effect of NH 2 -terminal acetylation on the oxygenation properties of vertebrate haemoglobin
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Includes: Supplementary data
Articles

Genetic activity during early plant embryogenesis

Open Access
Ran Tian, Priyanka Paul, Sanjay Joshi, Sharyn E. Perry
Journal: Biochemical Journal
Biochem J (2020) 477 (19): 3743–3767.
https://doi.org/10.1042/BCJ20190161
Published: 12 October 2020
View article titled, Genetic activity during early plant embryogenesis
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Includes: Supplementary data
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The ever-expanding limits of enzyme catalysis and biodegradation: polyaromatic, polychlorinated, polyfluorinated, and polymeric compounds

Open Access
Lawrence P. Wackett, Serina L. Robinson
Journal: Biochemical Journal
Biochem J (2020) 477 (15): 2875–2891.
https://doi.org/10.1042/BCJ20190720
Published: 14 August 2020
View article titled, The ever-expanding limits of enzyme catalysis and biodegradation: polyaromatic, polychlorinated, polyfluorinated, and polymeric compounds
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Articles

Structure-based enzyme engineering improves donor-substrate recognition of Arabidopsis thaliana glycosyltransferases

Open Access
Aishat Akere, Serena H. Chen, Xiaohan Liu, Yanger Chen, Sarath Chandra Dantu, Alessandro Pandini, Debsindhu Bhowmik, Shozeb Haider
Journal: Biochemical Journal
Biochem J (2020) 477 (15): 2791–2805.
https://doi.org/10.1042/BCJ20200477
Published: 07 August 2020
View article titled, Structure-based enzyme engineering improves donor-substrate recognition of Arabidopsis thaliana glycosyltransferases
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Includes: Supplementary data
Articles

Insights into the unique carboxylation reactions in the metabolism of propylene and acetone

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Florence Mus, Hsin-Hua Wu, Alexander B. Alleman, Krista A. Shisler, Oleg A. Zadvornyy, Brian Bothner, Jennifer L. Dubois, John W. Peters
Journal: Biochemical Journal
Biochem J (2020) 477 (11): 2027–2038.
https://doi.org/10.1042/BCJ20200174
Published: 04 June 2020
View article titled, Insights into the unique carboxylation reactions in the metabolism of propylene and acetone
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Articles

Silencing of lncRNA 6030408B16RIK prevents ultrafiltration failure in peritoneal dialysis via microRNA-326-3p-mediated WISP2 down-regulation

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Zhikui Wang, Zhongqi Zhou, Wenjie Ji, Lina Sun, Yulin Man, Jifeng Wang, Hongjuan Zhang
Journal: Biochemical Journal
Biochem J (2020) 477 (10): 1907–1921.
https://doi.org/10.1042/BCJ20190877
Published: 29 May 2020
View article titled, Silencing of lncRNA 6030408B16RIK prevents ultrafiltration failure in peritoneal dialysis via microRNA-326-3p-mediated WISP2 down-regulation
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Articles

A steady-state approach for inhibition of heterogeneous enzyme reactions

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Jeppe Kari, Corinna Schiano-di-Cola, Stine Fredslund Hansen, Silke Flindt Badino, Trine Holst Sørensen, Ana Mafalda Cavaleiro, Kim Borch, Peter Westh
Journal: Biochemical Journal
Biochem J (2020) 477 (10): 1971–1982.
https://doi.org/10.1042/BCJ20200083
Published: 29 May 2020
View article titled, A steady-state approach for inhibition of heterogeneous enzyme reactions
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Includes: Supplementary data
Articles

Development of novel anti-malarial from structurally diverse library of molecules, targeting plant-like CDPK1, a multistage growth regulator of P. falciparum

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Ravi Jain, Sakshi Gupta, Manoj Munde, Soumya Pati, Shailja Singh
Journal: Biochemical Journal
Biochem J (2020) 477 (10): 1951–1970.
https://doi.org/10.1042/BCJ20200045
Published: 29 May 2020
View article titled, Development of novel anti-malarial from structurally diverse library of molecules, targeting plant-like CDPK1, a multistage growth regulator of P. falciparum
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Includes: Supplementary data
Articles

Effects of CGA-N12 on the membrane structure of Candida tropicalis cells

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Ruifang Li, Weini Shi, Ruiling Zhang, Liang Huang, Yanjie Yi, Aihua Li, Hongjuan Jing, Mengke Tao, Meng Zhang, Nanqi Pei
Journal: Biochemical Journal
Biochem J (2020) 477 (10): 1813–1825.
https://doi.org/10.1042/BCJ20190939
Published: 21 May 2020
View article titled, Effects of CGA-N12 on the membrane structure of Candida tropicalis cells
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Articles

Kringles of substrate plasminogen provide a ‘catalytic switch' in plasminogen to plasmin turnover by Streptokinase

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Vandna Sharma, Shekhar Kumar, Girish Sahni
Journal: Biochemical Journal
Biochem J (2020) 477 (5): 953–970.
https://doi.org/10.1042/BCJ20190909
Published: 06 March 2020
View article titled, Kringles of substrate plasminogen provide a ‘catalytic switch' in plasminogen to plasmin turnover by Streptokinase
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