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Cardiovascular System & Vascular Biology
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Articles
Cardiac substrate metabolism in type 2 diabetes
Open Access
Journal:
Biochemical Journal
Biochem J (2025) 482 (10): 499–518.
Published: 13 May 2025
Articles
Biochemical basis and therapeutic potential of mitochondrial uncoupling in cardiometabolic syndrome
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2024) 481 (23): 1831–1854.
Published: 04 December 2024
Articles
Felix Hong, Molly Y. Mollica, Kalyan Golla, Enoli De Silva, Nathan J. Sniadecki, José A. López, Hugh Kim
Journal:
Biochemical Journal
Biochem J (2024) 481 (20): 1395–1410.
Published: 07 October 2024
Includes: Supplementary data
Articles
Lipoprotein(a) and cardiovascular disease
Open Access
Journal:
Biochemical Journal
Biochem J (2024) 481 (19): 1277–1296.
Published: 20 September 2024
Articles
Mesenteric artery smooth muscle cells from hypertensive rats have increased microtubule acetylation
Open AccessAnthony M. Mozzicato, Joakim A. Bastrup, Jose L. Sanchez-Alonso, Jennifer van der Horst, Julia Gorelik, Per Hägglund, Thomas A. Jepps
Journal:
Biochemical Journal
Biochem J (2024) 481 (5): 387–403.
Published: 29 February 2024
Includes: Supplementary data
Articles
RyR2 C-terminal truncating variants identified in patients with arrhythmic phenotypes exert a dominant negative effect through formation of wildtype-truncation heteromers
Available to PurchaseShanshan Tian, Xiaowei Zhong, Hui Wang, Jinhong Wei, Wenting Guo, Ruiwu Wang, John Paul Estillore, Carlo Napolitano, Henry H. Duff, Erkan Ilhan, Linda M. Knight, Michael S. Lloyd, Jason D. Roberts, Silvia G. Priori, S.R. Wayne Chen
Journal:
Biochemical Journal
Biochem J (2023) 480 (17): 1379–1395.
Published: 01 September 2023
Articles
RhoGAP6 interacts with COPI to regulate protein transport
Available to PurchaseLorna O'Donoghue, Shane P. Comer, Dishon W. Hiebner, Ingmar Schoen, Alex von Kriegsheim, Albert Smolenski
Journal:
Biochemical Journal
Biochem J (2023) 480 (14): 1109–1127.
Published: 19 July 2023
Articles
Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2022) 479 (22): 2351–2364.
Published: 23 November 2022
Includes: Supplementary data
Articles
Jacqueline J.T. Marshall, Joshua J. Cull, Hajed O. Alharbi, May Zaw Thin, Susanna T.E. Cooper, Christopher Barrington, Hannah Vanyai, Thomas Snoeks, Bernard Siow, Alejandro Suáarez-Bonnet, Eleanor Herbert, Daniel J. Stuckey, Angus J.M. Cameron, Fabrice Prin, Andrew C. Cook, Simon L. Priestnall, Sonia Chotani, Owen J. L. Rackham, Daniel N. Meijles, Tim Mohun, Angela Clerk, Peter J. Parker
Journal:
Biochemical Journal
Biochem J (2022) 479 (13): 1467–1486.
Published: 12 July 2022
Includes: Multimedia, Supplementary data
Articles
Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2022) 479 (6): 731–750.
Published: 28 March 2022
Articles
Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo
Open AccessAngela Clerk, Daniel N. Meijles, Michelle A. Hardyman, Stephen J. Fuller, Sonia P. Chothani, Joshua J. Cull, Susanna T.E. Cooper, Hajed O. Alharbi, Konstantinos Vanezis, Leanne E. Felkin, Thomais Markou, Samuel J. Leonard, Spencer W. Shaw, Owen J.L. Rackham, Stuart A. Cook, Peter E. Glennon, Mary N. Sheppard, John C. Sembrat, Mauricio Rojas, Charles F. McTiernan, Paul J. Barton, Peter H. Sugden
Journal:
Biochemical Journal
Biochem J (2022) 479 (3): 401–424.
Published: 11 February 2022
Includes: Supplementary data
Articles
Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy
Open AccessJinxi Wang, Grace Ciampa, Dong Zheng, Qian Shi, Biyi Chen, E. Dale Abel, Tianqing Peng, Duane D. Hall, Long-Sheng Song
Journal:
Biochemical Journal
Biochem J (2021) 478 (19): 3539–3553.
Published: 06 October 2021
Articles
Stephen J. Fuller, Nick S. Edmunds, Liam J. McGuffin, Michelle A. Hardyman, Joshua J. Cull, Hajed O. Alharbi, Daniel N. Meijles, Peter H. Sugden, Angela Clerk
Journal:
Biochemical Journal
Biochem J (2021) 478 (11): 2121–2143.
Published: 11 June 2021
Includes: Supplementary data
Articles
Daniel N. Meijles, Stephen J. Fuller, Joshua J. Cull, Hajed O. Alharbi, Susanna T.E. Cooper, Peter H. Sugden, Angela Clerk
Journal:
Biochemical Journal
Biochem J (2021) 478 (11): 2059–2079.
Published: 08 June 2021
Includes: Supplementary data
Articles
Characterization of tolloid-mediated cleavage of the GDF8 procomplex
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (9): 1733–1747.
Published: 10 May 2021
Includes: Supplementary data
Articles
Role of macrophage autophagy in atherosclerosis: modulation by bioactive compounds
Available to PurchaseMD Khurshidul Zahid, Hazera Binte Sufian, Mahua Choudhury, Masao Yamasaki, Ahmed Al-Harrasi, Naima Moustaid-Moussa, Shaikh Mizanoor Rahman
Journal:
Biochemical Journal
Biochem J (2021) 478 (7): 1359–1375.
Published: 16 April 2021
Articles
Stability of Smyd1 in endothelial cells is controlled by PML-dependent SUMOylation upon cytokine stimulation
Available to PurchaseSamuel Becker, Gustav Steinemann, Weronika Karle, Kerrin Roos, Celine Huajia Liem, Shalini Muralikumar, Andrea Volkamer, Barbara Munz, Andreas Zakrzewicz, Janine Berkholz
Journal:
Biochemical Journal
Biochem J (2021) 478 (1): 217–234.
Published: 15 January 2021
Includes: Supplementary data
Articles
Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics
Available to PurchaseAgnès Ribes, Antoine Oprescu, Julien Viaud, Karim Hnia, Gaëtan Chicanne, Jean-Marie Xuereb, Sonia Severin, Marie-Pierre Gratacap, Bernard Payrastre
Journal:
Biochemical Journal
Biochem J (2020) 477 (22): 4327–4342.
Published: 26 November 2020
Articles
Maurocalcin and its analog MCa E12A facilitate Ca 2+ mobilization in cardiomyocytes
Available to PurchaseStephan De Waard, Jérome Montnach, Charly Cortinovis, Olfa Chkir, Morteza Erfanian, Philippe Hulin, Nathalie Gaborit, Patricia Lemarchand, Pietro Mesirca, Isabelle Bidaud, Matteo E. Mangoni, Michel De Waard, Michel Ronjat
Journal:
Biochemical Journal
Biochem J (2020) 477 (20): 3985–3999.
Published: 29 October 2020
Includes: Supplementary data
Articles
Role of sialidase Neu3 and ganglioside GM3 in cardiac fibroblasts activation
Available to PurchaseAndrea Ghiroldi, Marco Piccoli, Pasquale Creo, Federica Cirillo, Paola Rota, Sara D'Imperio, Giuseppe Ciconte, Michelle M. Monasky, Emanuele Micaglio, Andrea Garatti, Massimo Aureli, Emma Veronica Carsana, Lorenzo Menicanti, Carlo Pappone, Luigi Anastasia
Journal:
Biochemical Journal
Biochem J (2020) 477 (17): 3401–3415.
Published: 17 September 2020
Includes: Supplementary data
Articles
Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495
Available to PurchaseKatrin Spengler, Darya Zibrova, Angela Woods, Christopher G. Langendorf, John W. Scott, David Carling, Regine Heller
Journal:
Biochemical Journal
Biochem J (2020) 477 (17): 3453–3469.
Published: 17 September 2020
Includes: Supplementary data
Articles
Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (17): 3313–3327.
Published: 10 September 2020
Includes: Supplementary data
Articles
Heart failure and the glutathione cycle: an integrated view
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (17): 3123–3130.
Published: 04 September 2020
Articles
The SGLT2 inhibitor canagliflozin suppresses lipid synthesis and interleukin-1 beta in ApoE deficient mice
Available to PurchaseIn Collection
Celebrating 100 years of insulin research
Emily A. Day, Rebecca J. Ford, Jessie H. Lu, Rachel Lu, Lucie Lundenberg, Eric M. Desjardins, Alex E. Green, James S.V. Lally, Jonathan D. Schertzer, Gregory R. Steinberg
Journal:
Biochemical Journal
Biochem J (2020) 477 (12): 2347–2361.
Published: 26 June 2020
Includes: Supplementary data
Articles
Ubiquitination-activating enzymes UBE1 and UBA6 regulate ubiquitination and expression of cardiac sodium channel Na v 1.5
Available to PurchaseYushuang Hu, Xuemei Bai, Chi Zhang, Susmita Chakrabarti, Bo Tang, Hongbo Xiong, Zhijie Wang, Gang Yu, Chengqi Xu, Qiuyun Chen, Qing Kenneth Wang
Journal:
Biochemical Journal
Biochem J (2020) 477 (9): 1683–1700.
Published: 11 May 2020
Articles
Journal:
Biochemical Journal
Biochem J (2020) 477 (5): 925–935.
Published: 06 March 2020
Includes: Supplementary data
Articles
Sean Brennan, Hussein N. Rubaiy, Saba Imanzadeh, Ruth Reid, David Lodwick, Robert I. Norman, Richard D. Rainbow
Journal:
Biochemical Journal
Biochem J (2020) 477 (3): 671–689.
Published: 11 February 2020
Articles
Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice
Available to PurchaseAlessandro G. Salerno, Thiago Rentz, Gabriel G. Dorighello, Ana Carolina Marques, Estela Lorza-Gil, Amarylis C. B. A. Wanschel, Audrey de Moraes, Anibal E. Vercesi, Helena C. F. Oliveira
Journal:
Biochemical Journal
Biochem J (2019) 476 (24): 3769–3789.
Published: 20 December 2019
Includes: Supplementary data
Articles
Regulation of plasma glycero-lysophospholipid levels by lipoprotein metabolism
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2019) 476 (23): 3565–3581.
Published: 03 December 2019
Includes: Supplementary data
Articles
Calcium-induced dissociation of CIB1 from ASK1 regulates agonist-induced activation of the p38 MAPK pathway in platelets
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2019) 476 (19): 2835–2850.
Published: 11 October 2019
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2019) 476 (19): 2909–2926.
Published: 11 October 2019
Includes: Supplementary data
Articles
Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2019) 476 (19): 2769–2795.
Published: 11 October 2019
Includes: Supplementary data
Articles
Proline residues in scavenger receptor-BI's C-terminal region support efficient cholesterol transport
Open Access
Journal:
Biochemical Journal
Biochem J (2019) 476 (6): 951–963.
Published: 22 March 2019
Articles
Articles
Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction
Available to PurchaseSahar I. Da'as, Khalid Fakhro, Angelos Thanassoulas, Navaneethakrishnan Krishnamoorthy, Alaaeldin Saleh, Brian L. Calver, Bared Safieh-Garabedian, Egon Toft, George Nounesis, F. Anthony Lai, Michail Nomikos
Journal:
Biochemical Journal
Biochem J (2018) 475 (24): 3933–3948.
Published: 14 December 2018
Includes: Supplementary data
Articles
Articles
Cytosolic carnitine acetyltransferase as a source of cytosolic acetyl-CoA: a possible mechanism for regulation of cardiac energy metabolism
Available to PurchaseTariq R. Altamimi, Panakkezhum D. Thomas, Ahmed M. Darwesh, Natasha Fillmore, Mohammad U. Mahmoud, Liyan Zhang, Abhishek Gupta, Rami Al Batran, John M. Seubert, Gary D. Lopaschuk
Journal:
Biochemical Journal
Biochem J (2018) 475 (5): 959–976.
Published: 09 March 2018
Includes: Supplementary data
Articles
In Collection
Editors' pick of review article highlights published in the Biochemical Journal in 2018 & 2019
Journal:
Biochemical Journal
Biochem J (2018) 475 (5): 839–852.
Published: 06 March 2018
Articles
Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARγ/RXR and RAR/RXR: down-regulation of CYP27A1–LXRα signaling
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (3): 621–642.
Published: 09 February 2018
Includes: Supplementary data
Articles
Reduced expression of cardiac ryanodine receptor protects against stress-induced ventricular tachyarrhythmia, but increases the susceptibility to cardiac alternans
Available to PurchaseXiaowei Zhong, Alexander Vallmitjana, Bo Sun, Zhichao Xiao, Wenting Guo, Jinhong Wei, Mingke Ni, Yongxiang Chen, Edward R. O'Brien, Anne M. Gillis, Masahiko Hoshijima, Hiroshi Takeshima, Leif Hove-Madsen, Raul Benitez, Darrell Belke, S.R. Wayne Chen
Journal:
Biochemical Journal
Biochem J (2018) 475 (1): 169–183.
Published: 05 January 2018
Articles
Suppression of store-operated Ca 2+ entry by activation of GPER: contribution to a clamping effect on endothelial Ca 2+ signaling
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2017) 474 (21): 3627–3642.
Published: 23 October 2017
Articles
Reduced threshold for store overload-induced Ca 2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease
Available to PurchaseWenqian Chen, Andrea Koop, Yingjie Liu, Wenting Guo, Jinhong Wei, Ruiwu Wang, David H. MacLennan, Robert T. Dirksen, Sui Rong Wayne Chen
Journal:
Biochemical Journal
Biochem J (2017) 474 (16): 2749–2761.
Published: 07 August 2017
Articles
Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes
Open AccessAndrew A. Gibb, Pawel K. Lorkiewicz, Yu-Ting Zheng, Xiang Zhang, Aruni Bhatnagar, Steven P. Jones, Bradford G. Hill
Journal:
Biochemical Journal
Biochem J (2017) 474 (16): 2785–2801.
Published: 07 August 2017
Articles
CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading
Available to PurchaseKoichi Miura, Takashi Nojiri, Yoshiharu Akitake, Koji Ando, Shigetomo Fukuhara, Masahiro Zenitani, Toru Kimura, Jun Hino, Mikiya Miyazato, Hiroshi Hosoda, Kenji Kangawa
Journal:
Biochemical Journal
Biochem J (2017) 474 (11): 1897–1918.
Published: 19 May 2017
Includes: Multimedia, Supplementary data
Articles
The sweet side of AMPK signaling: regulation of GFAT1
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2017) 474 (7): 1289–1292.
Published: 23 March 2017
Articles
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis
Available to PurchaseDarya Zibrova, Franck Vandermoere, Olga Göransson, Mark Peggie, Karina V. Mariño, Anne Knierim, Katrin Spengler, Cora Weigert, Benoit Viollet, Nicholas A. Morrice, Kei Sakamoto, Regine Heller
Journal:
Biochemical Journal
Biochem J (2017) 474 (6): 983–1001.
Published: 07 March 2017
Includes: Supplementary data
Articles
NOD1 activation in cardiac fibroblasts induces myocardial fibrosis in a murine model of type 2 diabetes
Available to PurchaseAlmudena Val-Blasco, Patricia Prieto, Silvia Gonzalez-Ramos, Gemma Benito, María Teresa Vallejo-Cremades, Ivette Pacheco, Pilar González-Peramato, Noelia Agra, Verónica Terrón, Carmen Delgado, Paloma Martín-Sanz, Lisardo Boscá, María Fernández-Velasco
Journal:
Biochemical Journal
Biochem J (2017) 474 (3): 399–410.
Published: 20 January 2017
Includes: Supplementary data
Articles
Molecular mapping of α-thrombin (αT)/β2-glycoprotein I (β2GpI) interaction reveals how β2GpI affects αT functions
Available to PurchaseLaura Acquasaliente, Daniele Peterle, Simone Tescari, Nicola Pozzi, Vittorio Pengo, Vincenzo De Filippis
Journal:
Biochemical Journal
Biochem J (2016) 473 (24): 4629–4650.
Published: 09 December 2016
Includes: Supplementary data
Articles
Nebivolol suppresses cardiac ryanodine receptor-mediated spontaneous Ca 2+ release and catecholaminergic polymorphic ventricular tachycardia
Available to PurchaseZhen Tan, Zhichao Xiao, Jinhong Wei, Jingqun Zhang, Qiang Zhou, Chris D. Smith, Alma Nani, Guogen Wu, Long-Sheng Song, Thomas G. Back, Michael Fill, S. R. Wayne Chen
Journal:
Biochemical Journal
Biochem J (2016) 473 (22): 4159–4172.
Published: 10 November 2016
Articles
Histone H2AK119 and H2BK120 mono-ubiquitination modulate SET7/9 and SUV39H1 in type 1 diabetes-induced renal fibrosis
Available to PurchaseSantosh Kumar Goru, Almesh Kadakol, Anuradha Pandey, Vajir Malek, Nisha Sharma, Anil Bhanudas Gaikwad
Journal:
Biochemical Journal
Biochem J (2016) 473 (21): 3937–3949.
Published: 27 October 2016
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