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Cell Homeostasis & Autophagy
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Articles
Insights into the cellular function and mechanism of action of quinone reductase 2 (NQO2)
Open Access
Journal:
Biochemical Journal
Biochem J (2025) 482 (06): 309–324.
Published: 11 March 2025
Articles
Journal:
Biochemical Journal
Biochem J (2024) 481 (8): 587–599.
Published: 22 April 2024
Includes: Supplementary data
Articles
Articles
The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress
Open Access
Journal:
Biochemical Journal
Biochem J (2024) 481 (4): 265–278.
Published: 15 February 2024
Includes: Supplementary data
Articles
Articles
Proteotoxic stresses stimulate dissociation of UBL4A from the tail-anchored protein recognition complex
Open Access
Journal:
Biochemical Journal
Biochem J (2023) 480 (19): 1583–1598.
Published: 11 October 2023
Includes: Supplementary data
Articles
ISGylation-independent protection of cell growth by USP18 following interferon stimulation
Open AccessAnne Clancy, Emma V. Rusilowicz-Jones, Iona Wallace, Kirby N. Swatek, Sylvie Urbé, Michael J. Clague
Journal:
Biochemical Journal
Biochem J (2023) 480 (19): 1571–1581.
Published: 09 October 2023
Articles
Lhs1 dependent ERAD is determined by transmembrane domain context
Available to PurchaseMaria Sukhoplyasova, Abigail M. Keith, Emma M. Perrault, Hannah E. Vorndran, Alexa S. Jordahl, Megan E. Yates, Ashutosh Pastor, Zachary Li, Michael L. Freaney, Riddhi A. Deshpande, David B. Adams, Christopher J. Guerriero, Shujie Shi, Thomas R. Kleyman, Ossama B. Kashlan, Jeffrey L. Brodsky, Teresa M. Buck
Journal:
Biochemical Journal
Biochem J (2023) 480 (18): 1459–1473.
Published: 21 September 2023
Includes: Supplementary data
Articles
In Collection
Awards
Journal:
Biochemical Journal
Biochem J (2022) 479 (18): 1917–1940.
Published: 23 September 2022
Includes: Supplementary data
Articles
The role of eIF2 phosphorylation in cell and organismal physiology: new roles for well-known actors
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2022) 479 (10): 1059–1082.
Published: 23 May 2022
Articles
Articles
The complex interplay between autophagy and cell death pathways
Available to PurchaseIn Collection
Cell death and survival
Journal:
Biochemical Journal
Biochem J (2022) 479 (1): 75–90.
Published: 14 January 2022
Articles
SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain
Available to PurchasePatrick G. Needham, Jennifer L. Goeckeler-Fried, Casey Zhang, Zhihao Sun, Adam R. Wetzel, Carol A. Bertrand, Jeffrey L. Brodsky
Journal:
Biochemical Journal
Biochem J (2021) 478 (24): 4203–4220.
Published: 23 December 2021
Includes: Supplementary data
Articles
Richard Campion, Leanne Bloxam, Kimberley Burrow, Philip J. Brownridge, Daniel R. Pentland, Patricia Thomas, Campbell W. Gourlay, Claire E. Eyers, Jeff W. Barclay, Alan Morgan
Journal:
Biochemical Journal
Biochem J (2021) 478 (24): 4153–4167.
Published: 16 December 2021
Includes: Supplementary data
Articles
Articles
Molecular mechanisms of mammalian autophagy
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (18): 3395–3421.
Published: 23 September 2021
Articles
Decoding the consecutive lysosomal degradation of 3- O -sulfate containing heparan sulfate by Arylsulfatase G (ARSG)
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (17): 3221–3237.
Published: 07 September 2021
Includes: Supplementary data
Articles
Quality control of protein import into mitochondria
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (16): 3125–3143.
Published: 26 August 2021
Articles
Structural and molecular bases to IRE1 activity modulation
Available to PurchaseTimothy Langlais, Diana Pelizzari-Raymundo, Sayyed Jalil Mahdizadeh, Nicolas Gouault, Francois Carreaux, Eric Chevet, Leif A. Eriksson, Xavier Guillory
Journal:
Biochemical Journal
Biochem J (2021) 478 (15): 2953–2975.
Published: 10 August 2021
Articles
Articles
Characterization of the structural determinants of the ubiquitin-dependent proteasomal degradation of human hepatic tryptophan 2,3-dioxygenase
Available to PurchaseYi Liu, Sung-Mi Kim, YongQiang Wang, Shay Karkashon, Ariel Lewis-Ballester, Syun-Ru Yeh, Maria Almira Correia
Journal:
Biochemical Journal
Biochem J (2021) 478 (10): 1999–2017.
Published: 28 May 2021
Includes: Supplementary data
Articles
Understanding amphisomes
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (10): 1959–1976.
Published: 28 May 2021
Articles
Casting iron into the cell fate mold
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (10): 1879–1883.
Published: 24 May 2021
Articles
Plasmodium falciparum Atg18 localizes to the food vacuole via interaction with the multi-drug resistance protein 1 and phosphatidylinositol 3-phosphate
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (9): 1705–1732.
Published: 10 May 2021
Includes: Supplementary data
Articles
Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis
Available to PurchaseMaria E. Solesio, Lihan Xie, Brendan McIntyre, Mathew Ellenberger, Erna Mitaishvili, Siddharth Bhadra-Lobo, Lisa F. Bettcher, Jason N. Bazil, Daniel Raftery, Ursula Jakob, Evgeny V. Pavlov
Journal:
Biochemical Journal
Biochem J (2021) 478 (8): 1631–1646.
Published: 30 April 2021
Includes: Supplementary data
Articles
Role of macrophage autophagy in atherosclerosis: modulation by bioactive compounds
Available to PurchaseMD Khurshidul Zahid, Hazera Binte Sufian, Mahua Choudhury, Masao Yamasaki, Ahmed Al-Harrasi, Naima Moustaid-Moussa, Shaikh Mizanoor Rahman
Journal:
Biochemical Journal
Biochem J (2021) 478 (7): 1359–1375.
Published: 16 April 2021
Articles
Bulk autophagy induction and life extension is achieved when iron is the only limited nutrient in Saccharomyces cerevisiae
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (4): 811–837.
Published: 24 February 2021
Articles
Amyloid-beta oligomers induce Parkin-mediated mitophagy by reducing Miro1
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (23): 4581–4597.
Published: 08 December 2020
Includes: Supplementary data
Articles
PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability
Available to PurchaseSandra M. Martín-Guerrero, Pedro Casado, Maruan Hijazi, Vinothini Rajeeve, Julio Plaza-Díaz, Francisco Abadía-Molina, Julio Navascués, Miguel A. Cuadros, Pedro R. Cutillas, David Martín-Oliva
Journal:
Biochemical Journal
Biochem J (2020) 477 (23): 4491–4513.
Published: 03 December 2020
Includes: Supplementary data
Articles
Insights into the regulation of the matriptase-prostasin proteolytic system
Available to PurchaseLasse Holt-Danborg, Signe Skovbjerg, Kristian W. Goderum, Annika W. Nonboe, Evelina Stankevic, Ásdis K. Frost, Lars Vitved, Jan K. Jensen, Lotte K. Vogel
Journal:
Biochemical Journal
Biochem J (2020) 477 (22): 4349–4365.
Published: 26 November 2020
Includes: Supplementary data
Articles
Amino acid starvation inhibits autophagy in lipid droplet-deficient cells through mitochondrial dysfunction
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (18): 3613–3623.
Published: 28 September 2020
Includes: Supplementary data
Articles
Structural–functional diversity of malaria parasite's PfHSP70-1 and PfHSP40 chaperone pair gives an edge over human orthologs in chaperone-assisted protein folding
Available to PurchaseIn Collection
Protein structure and function
Mohammad Anas, Ankita Shukla, Aradhya Tripathi, Varsha Kumari, Chetan Prakash, Priyabrata Nag, L. Sathish Kumar, Sandeep K. Sharma, Ravishankar Ramachandran, Niti Kumar
Journal:
Biochemical Journal
Biochem J (2020) 477 (18): 3625–3643.
Published: 28 September 2020
Includes: Supplementary data
Articles
Structure, dynamics and functions of UBQLNs: at the crossroads of protein quality control machinery
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (18): 3471–3497.
Published: 23 September 2020
Articles
Mitochondrial control of cellular protein homeostasis
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (16): 3033–3054.
Published: 26 August 2020
Articles
Cr(VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (14): 2607–2619.
Published: 24 July 2020
Articles
Inhibition of an active zymogen protease: the zymogen form of matriptase is regulated by HAI-1 and HAI-2
Available to PurchaseSigne Skovbjerg, Lasse Holt-Danborg, Annika W. Nonboe, Zebin Hong, Ásdís K. Frost, Christine R. Schar, Cecilia C. Thomas, Lars Vitved, Jan K. Jensen, Lotte K. Vogel
Journal:
Biochemical Journal
Biochem J (2020) 477 (9): 1779–1794.
Published: 15 May 2020
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2020) 477 (8): 1499–1513.
Published: 29 April 2020
Includes: Supplementary data
Articles
A nonpeptidyl molecule modulates apoptosis-like cell death by inhibiting P. falciparum metacaspase-2
Available to PurchaseVandana, Sudha Shankar, Kona Madhavinadha Prasad, Mohammad Kashif, Inderjeet Kalia, Rajkishor Rai, Agam P. Singh, Kailash C. Pandey
Journal:
Biochemical Journal
Biochem J (2020) 477 (7): 1323–1344.
Published: 17 April 2020
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2020) 477 (5): 925–935.
Published: 06 March 2020
Includes: Supplementary data
Articles
The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets
Open AccessMaria Zachari, Julie M. Rainard, George C. Pandarakalam, Lindsay Robinson, Jonathan Gillespie, Muralikrishnan Rajamanickam, Veronique Hamon, Angus Morrison, Ian G. Ganley, Stuart P. McElroy
Journal:
Biochemical Journal
Biochem J (2020) 477 (4): 801–814.
Published: 27 February 2020
Includes: Supplementary data
Articles
MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy
Available to PurchaseFernanda M. Cerqueira, Noga Kozer, Anton Petcherski, Boris M. Baranovski, Dane Wolf, Essam A. Assali, Yaelle Roth, Roi Gazit, Haim Barr, Eli C. Lewis, Guy Las, Orian S. Shirihai
Journal:
Biochemical Journal
Biochem J (2020) 477 (2): 461–475.
Published: 31 January 2020
Includes: Supplementary data
Articles
PAQR9 Modulates BAG6-mediated protein quality control of mislocalized membrane proteins
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (2): 477–489.
Published: 31 January 2020
Includes: Supplementary data
Articles
Nicola A. Scott, Laura J. Sharpe, Isabelle M. Capell-Hattam, Samuel J. Gullo, Winnie Luu, Andrew J. Brown
Journal:
Biochemical Journal
Biochem J (2020) 477 (2): 541–555.
Published: 31 January 2020
Includes: Supplementary data
Articles
A lysosome independent role for TFEB in activating DNA repair and inhibiting apoptosis in breast cancer cells
Available to PurchaseLogan Slade, Dipsikha Biswas, Francis Ihionu, Yassine El Hiani, Petra C. Kienesberger, Thomas Pulinilkunnil
Journal:
Biochemical Journal
Biochem J (2020) 477 (1): 137–160.
Published: 10 January 2020
Includes: Supplementary data
Articles
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
Available to PurchaseIn Collection
Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019
Apirat Chaikuad, Sebastian E. Koschade, Alexandra Stolz, Katarina Zivkovic, Christian Pohl, Shabnam Shaid, Huiyu Ren, Lester J. Lambert, Nicholas D.P. Cosford, Christian H. Brandts, Stefan Knapp
Journal:
Biochemical Journal
Biochem J (2019) 476 (5): 875–887.
Published: 12 March 2019
Includes: Supplementary data
Articles
Phosphatase of regenerating liver maintains cellular magnesium homeostasis
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (6): 1129–1139.
Published: 26 March 2018
Includes: Supplementary data
Articles
Emerging roles of endoplasmic reticulum-resident selenoproteins in the regulation of cellular stress responses and the implications for metabolic disease
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (6): 1037–1057.
Published: 20 March 2018
Articles
Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARγ/RXR and RAR/RXR: down-regulation of CYP27A1–LXRα signaling
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (3): 621–642.
Published: 09 February 2018
Includes: Supplementary data
Articles
Lipid-based DNA/siRNA transfection agents disrupt neuronal bioenergetics and mitophagy
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2017) 474 (23): 3887–3902.
Published: 10 November 2017
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2017) 474 (21): 3615–3626.
Published: 23 October 2017
Includes: Supplementary data
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