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Articles

Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300

Open Access
Dustin C. Becht, Soumi Biswas, Chenxi Xu, Hongwen Xuan, Moustafa Khalil, Ling Cai, Catherine A. Musselman, Xin Liu, El Bachir Affar, Xiaobing Shi, Gang Greg Wang, Tatiana G. Kutateladze
Journal: Biochemical Journal
Biochem J (2025) 482 (13): 955–968.
https://doi.org/10.1042/BCJ20253037
Published: 02 July 2025
View articletitled, Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300
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Includes: Supplementary data
Articles

Cas11 augments Cascade functions in type I-E CRISPR system but is redundant for gene silencing and plasmid interference

Open Access
Neha Pandey, Chitra Seetharam Misra, Devashish Rath
Journal: Biochemical Journal
Biochem J (2025) 482 (12): 793–805.
https://doi.org/10.1042/BCJ20253056
Published: 11 June 2025
View articletitled, Cas11 augments Cascade functions in type I-E CRISPR system but is redundant for gene silencing and plasmid interference
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Includes: Supplementary data
Articles

Molecular basis and therapeutic implications of binary YAP On /YAP Off cancer classes

Open Access
Pinky Sharma, Yale S. Michaels, Joel D. Pearson
Journal: Biochemical Journal
Biochem J (2025) 482 (11): 741–761.
https://doi.org/10.1042/BCJ20253077
Published: 28 May 2025
View articletitled, Molecular basis and therapeutic implications of binary YAP On /YAP Off cancer classes
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Articles

The bacterial transcription terminator, Rho, functions as an RNA:DNA hybrid (RDH) helicase in vivo

Open Access
Ankita Bhosale, Ranjan Sen
Journal: Biochemical Journal
Biochem J (2025) 482 (11): 655–674.
https://doi.org/10.1042/BCJ20253089
Published: 26 May 2025
View articletitled, The bacterial transcription terminator, Rho, functions as an RNA:DNA hybrid (RDH) helicase in vivo
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Includes: Supplementary data
Articles

Unveiling the role of srbA sRNA in biofilm formation by regulating algU , mucA , rhlA , and rsmA in Pseudomonas aeruginosa

Open Access
Piyali Saha, Samir Kumar Mukherjee, Sk Tofajjen Hossain
Journal: Biochemical Journal
Biochem J (2025) 482 (11): 621–637.
https://doi.org/10.1042/BCJ20240650
Published: 23 May 2025
View articletitled, Unveiling the role of srbA sRNA in biofilm formation by regulating algU , mucA , rhlA , and rsmA in Pseudomonas aeruginosa
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Includes: Supplementary data
Articles

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor

Open Access
Qinglin Li, Yunpeng Bai, Sarah M. Cavender, Yiming Miao, Frederick Nguele Meke, Emily L. Lasse-Opsahl, Peipei Zhu, Gina M. Doody, W. Andy Tao, Zhong-Yin Zhang
Journal: Biochemical Journal
Biochem J (2025) 482 (07): 341–356.
https://doi.org/10.1042/BCJ20240626
Published: 10 April 2025
View articletitled, The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor
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Includes: Supplementary data
Articles

Trypanosomatid histones: the building blocks of the epigenetic code of highly divergent eukaryotes

Open Access
Josefina Ocampo, Santiago Carena, María del Rosario López, Valentina Sol Vela, Romina Trinidad Zambrano Siri, Sofia Antonella Balestra, Guillermo Daniel Alonso
Journal: Biochemical Journal
Biochem J (2025) 482 (06): 325–340.
https://doi.org/10.1042/BCJ20240543
Published: 14 March 2025
View articletitled, Trypanosomatid histones: the building blocks of the epigenetic code of highly divergent eukaryotes
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Articles

DNA binding of an RNA helicase bacterial transcription terminator

Open Access
Sriyans Jain, Abhijeet Behera, Ranjan Sen
Journal: Biochemical Journal
Biochem J (2025) 482 (03): 103–117.
https://doi.org/10.1042/BCJ20240452
Published: 31 January 2025
View articletitled, DNA binding of an RNA helicase bacterial transcription terminator
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Includes: Supplementary data
Articles

Expanding the tagging toolbox for visualizing translation live

Open Access
Rhiannon M. Sears, Nathan L. Nowling, Jake Yarbro, Ning Zhao
Journal: Biochemical Journal
Biochem J (2025) 482 (03): 147–165.
https://doi.org/10.1042/BCJ20240183
Published: 31 January 2025
View articletitled, Expanding the tagging toolbox for visualizing translation live
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Articles

Gα12 and Gα13 proteins are required for transforming growth factor-β-induced myofibroblast differentiation

Open Access
Eleanor B. Reed, Albert Sitikov, Kun Woo D. Shin, Robert B. Hamanaka, Rengül Cetin-Atalay, Gökhan M. Mutlu, Alexander A. Mongin, Nickolai O. Dulin
Journal: Biochemical Journal
Biochem J (2024) 481 (24): 1937–1948.
https://doi.org/10.1042/BCJ20240317
Published: 13 December 2024
View articletitled, Gα12 and Gα13 proteins are required for transforming growth factor-β-induced myofibroblast differentiation
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Includes: Supplementary data
Articles

Investigating the differential structural organization and gene expression regulatory networks of lamin A Ig fold domain mutants of muscular dystrophy

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Subarna Dutta, Vikas Kumar, Arnab Barua, Madavan Vasudevan
Journal: Biochemical Journal
Biochem J (2024) 481 (23): 1803–1827.
https://doi.org/10.1042/BCJ20240474
Published: 28 November 2024
View articletitled, Investigating the differential structural organization and gene expression regulatory networks of lamin A Ig fold domain mutants of muscular dystrophy
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Includes: Supplementary data
Articles

Epigenetics and alternative splicing in cancer: old enemies, new perspectives

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Madhura R. Pandkar, Sanjeev Shukla
Journal: Biochemical Journal
Biochem J (2024) 481 (21): 1497–1518.
https://doi.org/10.1042/BCJ20240221
Published: 18 October 2024
View articletitled, Epigenetics and alternative splicing in cancer: old enemies, new perspectives
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Articles

Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression

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Takumi Sato, Ryota Shizu, Ryonosuke Baba, Akira Ooka, Takuomi Hosaka, Yuichiro Kanno, Kouichi Yoshinari
Journal: Biochemical Journal
Biochem J (2024) 481 (18): 1173–1186.
https://doi.org/10.1042/BCJ20240172
Published: 06 September 2024
View articletitled, Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression
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Includes: Supplementary data
Articles

Thermoregulated transcriptomics: the molecular basis and biological significance of temperature-dependent alternative splicing

Open Access
Tom Haltenhof, Marco Preußner, Florian Heyd
Journal: Biochemical Journal
Biochem J (2024) 481 (15): 999–1013.
https://doi.org/10.1042/BCJ20230410
Published: 31 July 2024
View articletitled, Thermoregulated transcriptomics: the molecular basis and biological significance of temperature-dependent alternative splicing
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Articles

Insights into the mechanisms driven by H3K4 KMTs in pancreatic cancer

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In Collection
Epigenetics
Kayla C. LaRue-Nolan, Glancis Luzeena Raja Arul, Ashley N. Sigafoos, Jiaqi Shi, Martin E. Fernandez-Zapico
Journal: Biochemical Journal
Biochem J (2024) 481 (15): 983–997.
https://doi.org/10.1042/BCJ20230374
Published: 30 July 2024
View articletitled, Insights into the mechanisms driven by H3K4 KMTs in pancreatic cancer
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Articles

Inducible gene expression of IκB-kinase ε is dependent on nuclear factor-κB in human pulmonary epithelial cells

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Amandah Necker-Brown, Cora Kooi, Andrew J. Thorne, Akanksha Bansal, Mahmoud M. Mostafa, Priyanka Chandramohan, Alex Gao, Keerthana Kalyanaraman, Arya Milani, Sachman Gill, Andrei Georgescu, Sarah K. Sasse, Anthony N. Gerber, Richard Leigh, Robert Newton
Journal: Biochemical Journal
Biochem J (2024) 481 (14): 959–980.
https://doi.org/10.1042/BCJ20230461
Published: 12 July 2024
View articletitled, Inducible gene expression of IκB-kinase ε is dependent on nuclear factor-κB in human pulmonary epithelial cells
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Includes: Supplementary data
Articles

Aflatoxin biosynthesis regulators AflR and AflS: DNA binding affinity, stoichiometry, and kinetics

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Asmaa Abbas, Ranjit K. Prajapati, Emil Aalto-Setälä, Alexander A. Baykov, Anssi M. Malinen
Journal: Biochemical Journal
Biochem J (2024) 481 (12): 805–821.
https://doi.org/10.1042/BCJ20240084
Published: 17 June 2024
View articletitled, Aflatoxin biosynthesis regulators AflR and AflS: DNA binding affinity, stoichiometry, and kinetics
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Includes: Supplementary data
Articles

Mechanisms and pathologies of human mitochondrial DNA replication and deletion formation

Open Access
Tiago M. Bernardino Gomes, Amy E. Vincent, Katja E. Menger, James B. Stewart, Thomas J. Nicholls
Journal: Biochemical Journal
Biochem J (2024) 481 (11): 683–715.
https://doi.org/10.1042/BCJ20230262
Published: 28 May 2024
View articletitled, Mechanisms and pathologies of human mitochondrial DNA replication and deletion formation
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Articles

Epigenetic mechanisms linking early-life adversities and mental health

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In Collection
Epigenetics
Eduardo T. Cánepa, Bruno G. Berardino
Journal: Biochemical Journal
Biochem J (2024) 481 (10): 615–642.
https://doi.org/10.1042/BCJ20230306
Published: 09 May 2024
View articletitled, Epigenetic mechanisms linking early-life adversities and mental health
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Articles

Expression of neuronal NO synthase α- and β-isoforms in skeletal muscle of mice

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Oliver Baum
Journal: Biochemical Journal
Biochem J (2024) 481 (9): 601–613.
https://doi.org/10.1042/BCJ20230458
Published: 25 April 2024
View articletitled, Expression of neuronal NO synthase α- and β-isoforms in skeletal muscle of mice
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Articles

Dynamic interactions between SPX proteins, the ubiquitination machinery, and signalling molecules for stress adaptation at a whole-plant level

Open Access
Emma Collins, Huixia Shou, Chuanzao Mao, James Whelan, Ricarda Jost
Journal: Biochemical Journal
Biochem J (2024) 481 (5): 363–385.
https://doi.org/10.1042/BCJ20230163
Published: 29 February 2024
View articletitled, Dynamic interactions between SPX proteins, the ubiquitination machinery, and signalling molecules for stress adaptation at a whole-plant level
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Articles

AMP-activated protein kinase activation suppresses leptin expression independently of adipogenesis in primary murine adipocytes

Open Access
Sophia Bustraan, Jane Bennett, Chad Whilding, Betheney R. Pennycook, David Smith, Alexis R. Barr, Jon Read, David Carling, Alice Pollard
Journal: Biochemical Journal
Biochem J (2024) 481 (5): 345–362.
https://doi.org/10.1042/BCJ20240003
Published: 23 February 2024
View articletitled, AMP-activated protein kinase activation suppresses leptin expression independently of adipogenesis in primary murine adipocytes
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Includes: Supplementary data
Articles

Beyond the tail: the consequence of context in histone post-translational modification and chromatin research

Open Access
In Collection
Epigenetics
Ellen N. Weinzapfel, Karlie N. Fedder-Semmes, Zu-Wen Sun, Michael-Christopher Keogh
Journal: Biochemical Journal
Biochem J (2024) 481 (4): 219–244.
https://doi.org/10.1042/BCJ20230342
Published: 14 February 2024
View articletitled, Beyond the tail: the consequence of context in histone post-translational modification and chromatin research
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Articles

Pseudouridylation-mediated gene expression modulation

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Jonathan L. Chen, W.-Matthias Leeder, Pedro Morais, Hironori Adachi, Yi-Tao Yu
Journal: Biochemical Journal
Biochem J (2024) 481 (1): 1–16.
https://doi.org/10.1042/BCJ20230096
Published: 04 January 2024
View articletitled, Pseudouridylation-mediated gene expression modulation
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Articles

MicroRNA, miR-501 regulate the V(D)J recombination in B cells

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Rupa Kumari, Urbi Roy, Sagar Desai, Arannya S. Mondal, Rajshree R. Nair, Namrata Nilavar, Bibha Choudhary, Sathees C. Raghavan
Journal: Biochemical Journal
Biochem J (2023) 480 (24): 2061–2077.
https://doi.org/10.1042/BCJ20230250
Published: 20 December 2023
View articletitled, MicroRNA, miR-501 regulate the V(D)J recombination in B cells
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Includes: Supplementary data
Articles

Engineering of CYP82Y1, a cytochrome P450 monooxygenase: a key enzyme in noscapine biosynthesis in opium poppy

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Zahra Aghaali, Mohammad Reza Naghavi
Journal: Biochemical Journal
Biochem J (2023) 480 (23): 2009–2022.
https://doi.org/10.1042/BCJ20230243
Published: 08 December 2023
View articletitled, Engineering of CYP82Y1, a cytochrome P450 monooxygenase: a key enzyme in noscapine biosynthesis in opium poppy
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Articles

Lysine methylation signaling in skeletal muscle biology: from myogenesis to clinical insights

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In Collection
Epigenetics
Eric Cordeiro-Spinetti, Scott B. Rothbart
Journal: Biochemical Journal
Biochem J (2023) 480 (23): 1969–1986.
https://doi.org/10.1042/BCJ20230223
Published: 06 December 2023
View articletitled, Lysine methylation signaling in skeletal muscle biology: from myogenesis to clinical insights
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Articles

PHF1 compartmentalizes PRC2 via phase separation

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Genzhe Lu, Pilong Li
Journal: Biochemical Journal
Biochem J (2023) 480 (22): 1833–1844.
https://doi.org/10.1042/BCJ20230040
Published: 21 November 2023
View articletitled, PHF1 compartmentalizes PRC2 via phase separation
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Includes: Supplementary data
Articles

Microrchidia 2/histone deacetylase 1 complex regulates E-cadherin gene expression and function

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Liz Thomas, Namita Chutani, Krishna R, Asha S. Nair, Nanda Kumar Yellapu, Prashanthi Karyala, Suresh B. Pakala
Journal: Biochemical Journal
Biochem J (2023) 480 (20): 1675–1691.
https://doi.org/10.1042/BCJ20230304
Published: 19 October 2023
View articletitled, Microrchidia 2/histone deacetylase 1 complex regulates E-cadherin gene expression and function
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Includes: Supplementary data
Articles

Seasonal cold induces divergent structural/biochemical adaptations in different skeletal muscles of Columba livia : evidence for nonshivering thermogenesis in adult birds

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Punyadhara Pani, Gourabamani Swalsingh, Sunil Pani, Unmod Senapati, Bijayashree Sahu, Benudhara Pati, Subhasmita Rout, Naresh C. Bal
Journal: Biochemical Journal
Biochem J (2023) 480 (17): 1397–1409.
https://doi.org/10.1042/BCJ20230245
Published: 04 September 2023
View articletitled, Seasonal cold induces divergent structural/biochemical adaptations in different skeletal muscles of Columba livia : evidence for nonshivering thermogenesis in adult birds
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Includes: Supplementary data
Articles

Development of an OTUD1 ubiquitin variant inhibitor

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Qi Liu, Evan Mallette, Hui Zheng, Wei Zhang
Journal: Biochemical Journal
Biochem J (2023) 480 (16): 1317–1330.
https://doi.org/10.1042/BCJ20230119
Published: 25 August 2023
View articletitled, Development of an OTUD1 ubiquitin variant inhibitor
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Includes: Supplementary data
Articles

SUFU promotes GLI activity in a Hedgehog-independent manner in pancreatic cancer

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Brooke D. Paradise, Vladimir G. Gainullin, Luciana L. Almada, Ashley N. Sigafoos, Sandhya Sen, Renzo E. Vera, Glancis Luzeena Raja Arul, Murat Toruner, David R. Pease, Alina L. Gonzalez, Fatima M. Mentucci, Daniel H. Grasso, Martin E. Fernandez-Zapico
Journal: Biochemical Journal
Biochem J (2023) 480 (15): 1199–1216.
https://doi.org/10.1042/BCJ20220439
Published: 02 August 2023
View articletitled, SUFU promotes GLI activity in a Hedgehog-independent manner in pancreatic cancer
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Articles

Calcium signalling components underlying NPK homeostasis: potential avenues for exploration

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In Collection
Plants and climate change: the role of plants in achieving net zero
Sonam Pahuja, Malathi Bheri, Diksha Bisht, Girdhar K. Pandey
Journal: Biochemical Journal
Biochem J (2023) 480 (13): 1015–1034.
https://doi.org/10.1042/BCJ20230156
Published: 07 July 2023
View articletitled, Calcium signalling components underlying NPK homeostasis: potential avenues for exploration
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Articles

Respiratory epithelial cell types, states and fates in the era of single-cell RNA-sequencing

Open Access
Oleksandr Dudchenko, Jose Ordovas-Montanes, Colin D. Bingle
Journal: Biochemical Journal
Biochem J (2023) 480 (13): 921–939.
https://doi.org/10.1042/BCJ20220572
Published: 06 July 2023
View articletitled, Respiratory epithelial cell types, states and fates in the era of single-cell RNA-sequencing
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Articles

Root system growth and development responses to elevated CO 2 : underlying signalling mechanisms and role in improving plant CO 2 capture and soil C storage

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In Collection
Plants and climate change: the role of plants in achieving net zero
Liên Bach, Alain Gojon
Journal: Biochemical Journal
Biochem J (2023) 480 (11): 753–771.
https://doi.org/10.1042/BCJ20220245
Published: 02 June 2023
View articletitled, Root system growth and development responses to elevated CO 2 : underlying signalling mechanisms and role in improving plant CO 2 capture and soil C storage
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Articles

Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module

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Ishita Bardhan, Soumen Barman, Anirban Roy, Babu Sudhamalla
Journal: Biochemical Journal
Biochem J (2023) 480 (9): 629–647.
https://doi.org/10.1042/BCJ20230011
Published: 10 May 2023
View articletitled, Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module
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Includes: Supplementary data
Articles

Identification and characterization of the Doublesex gene and its mRNA isoforms in the brine shrimp Artemia franciscana

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Wen-Tao Wu, Lian-Ying Xu, Zhi-Jun Yan, Ning Bi, Cai-Yuan Cheng, Fan Yang, Wei-Jun Yang, Jin-Shu Yang
Journal: Biochemical Journal
Biochem J (2023) 480 (5): 385–401.
https://doi.org/10.1042/BCJ20220495
Published: 15 March 2023
View articletitled, Identification and characterization of the Doublesex gene and its mRNA isoforms in the brine shrimp Artemia franciscana
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Includes: Supplementary data
Articles

The NFkB activation domain is 14-amino-acid-long variant of the 9aaTAD

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Josef Houser, Kristina Jendruchova, Andrea Knight, Martin Piskacek
Journal: Biochemical Journal
Biochem J (2023) 480 (5): 297–306.
https://doi.org/10.1042/BCJ20220605
Published: 09 March 2023
View articletitled, The NFkB activation domain is 14-amino-acid-long variant of the 9aaTAD
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Includes: Supplementary data
Articles

GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration

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Renzo E. Vera, María J. Lamberti, Luciana L. Almada, Ezequiel J. Tolosa, Anne M. Vrabel, Ashley N. Sigafoos, Merih D. Toruner, Luis F. Flores, Viviana A. Rivarola, Natalia B. Rumie Vittar, Martín E. Fernández-Zapico
Journal: Biochemical Journal
Biochem J (2023) 480 (3): 225–241.
https://doi.org/10.1042/BCJ20220521
Published: 14 February 2023
View articletitled, GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration
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Includes: Supplementary data
Articles

Characterizing crosstalk in epigenetic signaling to understand disease physiology

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In Collection
Cell signaling in the 21st century
Joanna K. Lempiäinen, Benjamin A. Garcia
Journal: Biochemical Journal
Biochem J (2023) 480 (1): 57–85.
https://doi.org/10.1042/BCJ20220550
Published: 11 January 2023
View articletitled, Characterizing crosstalk in epigenetic signaling to understand disease physiology
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Articles

Structural and functional organization of germ plasm condensates

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Austin Chiappetta, Jeffrey Liao, Siran Tian, Tatjana Trcek
Journal: Biochemical Journal
Biochem J (2022) 479 (24): 2477–2495.
https://doi.org/10.1042/BCJ20210815
Published: 19 December 2022
View articletitled, Structural and functional organization of germ plasm condensates
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Articles

Regulation of B cell receptor signalling by Epstein–Barr virus nuclear antigens

Open Access
Sarika Khasnis, Hildegonda Veenstra, Michael J. McClellan, Opeoluwa Ojeniyi, C. David Wood, Michelle J. West
Journal: Biochemical Journal
Biochem J (2022) 479 (23): 2395–2417.
https://doi.org/10.1042/BCJ20220417
Published: 07 December 2022
View articletitled, Regulation of B cell receptor signalling by Epstein–Barr virus nuclear antigens
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Includes: Supplementary data
Articles

Poly-ADP ribosylation of p21 by tankyrases promotes p21 degradation and regulates cell cycle progression

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Misun Jung, Wonyoung Kim, Jin Won Cho, Won Ho Yang, In Kwon Chung
Journal: Biochemical Journal
Biochem J (2022) 479 (22): 2379–2394.
https://doi.org/10.1042/BCJ20220391
Published: 30 November 2022
View articletitled, Poly-ADP ribosylation of p21 by tankyrases promotes p21 degradation and regulates cell cycle progression
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Includes: Supplementary data
Articles

The C-terminal region of phytoene synthase is a key element to control carotenoid biosynthesis in the haloarchaeon Haloferax volcanii

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Micaela Cerletti, Agustín Rabino, Roberto A. Paggi, Celeste Ferrari, Ansgar Poetsch, Harri Savilahti, Saija Kiljunen, Rosana E. De Castro
Journal: Biochemical Journal
Biochem J (2022) 479 (22): 2365–2377.
https://doi.org/10.1042/BCJ20220403
Published: 23 November 2022
View articletitled, The C-terminal region of phytoene synthase is a key element to control carotenoid biosynthesis in the haloarchaeon Haloferax volcanii
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Includes: Supplementary data
Articles

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells

Open Access
Jill E. Hunter, Amy E. Campbell, Scott Kerridge, Callum Fraser, Nicola L. Hannaway, Saimir Luli, Iglika Ivanova, Philip J. Brownridge, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S. R. Hasoon, Claire E. Eyers, Neil D. Perkins
Journal: Biochemical Journal
Biochem J (2022) 479 (19): 2131–2151.
https://doi.org/10.1042/BCJ20220103
Published: 14 October 2022
View articletitled, Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells
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Includes: Supplementary data
Articles

Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth

Open Access
Ksenija Korac, Devaraja Rajasekaran, Tyler Sniegowski, Bradley K. Schniers, Andrew F. Ibrahim, Yangzom D. Bhutia
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1807–1824.
https://doi.org/10.1042/BCJ20210851
Published: 06 September 2022
View articletitled, Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth
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Includes: Supplementary data
Articles

Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes

Open Access
Emily L. Button, Joseph J. Rossi, Daniel P. McDougal, John B. Bruning, Daniel J. Peet, David C. Bersten, Jill A. Rosenfeld, Murray L. Whitelaw
Journal: Biochemical Journal
Biochem J (2022) 479 (13): 1441–1454.
https://doi.org/10.1042/BCJ20220209
Published: 13 July 2022
View articletitled, Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes
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Includes: Supplementary data
Articles

Alphabetti kinase Spaghetti: the complex roles of IKKα and β in the canonical NF-κB pathway

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In Collection
Cell death and survival
Neil D. Perkins
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1121–1126.
https://doi.org/10.1042/BCJ20220023
Published: 01 June 2022
View articletitled, Alphabetti kinase Spaghetti: the complex roles of IKKα and β in the canonical NF-κB pathway
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Articles

The role of eIF2 phosphorylation in cell and organismal physiology: new roles for well-known actors

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Xuemin Wang, Christopher G. Proud
Journal: Biochemical Journal
Biochem J (2022) 479 (10): 1059–1082.
https://doi.org/10.1042/BCJ20220068
Published: 23 May 2022
View articletitled, The role of eIF2 phosphorylation in cell and organismal physiology: new roles for well-known actors
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Articles

No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors

Open Access
Justine Mailliot, Mirella Vivoli-Vega, Christiane Schaffitzel
Journal: Biochemical Journal
Biochem J (2022) 479 (9): 973–993.
https://doi.org/10.1042/BCJ20210556
Published: 12 May 2022
View articletitled, No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors
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