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Articles

Signalling by co-operative higher-order assembly formation: linking evidence at molecular and cellular levels

Bostjan Kobe, Jeffrey D. Nanson, Mikayla Hoad, Antje Blumenthal, Yann Gambin, Emma Sierecki, Katryn J. Stacey, Thomas Ve, Randal Halfmann
Journal: Biochemical Journal
Biochem J (2025) 482 (05): 275–294.
https://doi.org/10.1042/BCJ20220094
Published: 05 March 2025
View articletitled, Signalling by co-operative higher-order assembly formation: linking evidence at molecular and cellular levels
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Articles

Inhibition of RIPK1 or RIPK3 kinase activity post ischemia-reperfusion reduces the development of chronic kidney injury

Aspasia Pefanis, Anjan K. Bongoni, Jennifer L. McRae, Evelyn J. Salvaris, Nella Fisicaro, James M. Murphy, Francesco L. Ierino, Peter J. Cowan
Journal: Biochemical Journal
Biochem J (2025) 482 (2): 73–86.
https://doi.org/10.1042/BCJ20240569
Published: 21 January 2025
View articletitled, Inhibition of RIPK1 or RIPK3 kinase activity post ischemia-reperfusion reduces the development of chronic kidney injury
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Includes: Supplementary data
Articles

Pyroptotic executioner pore-forming protein gasdermin D forms oligomeric assembly and exhibits amyloid-like attributes that could contribute for its pore-forming function

Shamaita Chatterjee, Tarang Gupta, Gurvinder Kaur, Kausik Chattopadhyay
Journal: Biochemical Journal
Biochem J (2024) 481 (22): 1679–1705.
https://doi.org/10.1042/BCJ20240416
Published: 14 November 2024
View articletitled, Pyroptotic executioner pore-forming protein gasdermin D forms oligomeric assembly and exhibits amyloid-like attributes that could contribute for its pore-forming function
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Includes: Supplementary data
Articles

Mitigating neuroinflammation in cognitive areas: exploring the impact of HMG-CoA reductase inhibitor

Carlos Henrique Rocha Catalão, Luis Henrique Angenendt da Costa, Jonathas Rodrigo dos Santos, Luciane Carla Alberici, Luiz Luciano Falconi-Sobrinho, Norberto Cysne Coimbra, Diogo Dominguini, Felipe Dal-Pizzol, Tatiana Barichello, Maria José Alves Rocha
Journal: Biochemical Journal
Biochem J (2024) 481 (22): 1585–1602.
https://doi.org/10.1042/BCJ20240217
Published: 07 November 2024
View articletitled, Mitigating neuroinflammation in cognitive areas: exploring the impact of HMG-CoA reductase inhibitor
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Includes: Supplementary data
Articles

Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain

Yizhuo Wang, James E.B. Curson, Divya Ramnath, Kaustav Das Gupta, Robert C. Reid, Denuja Karunakaran, David P. Fairlie, Matthew J. Sweet
Journal: Biochemical Journal
Biochem J (2024) 481 (21): 1569–1584.
https://doi.org/10.1042/BCJ20240380
Published: 25 October 2024
View articletitled, Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain
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Articles

Revamped role for approved drug: integrative computational and biophysical analysis of saquinavir's peptidyl arginine deiminase 4 inhibition for rheumatoid arthritis

Indhumathi Thirugnanasambandham, Srikanth Jupudi, Parikshit Roychowdhury, Veera Venkata Satyanarayana Reddy Karri, Subba Rao V. Madhunapantula, Sachin Kumar Singh, Vetriselvan Subramaniyan, Gowthamarajan Kuppusamy
Journal: Biochemical Journal
Biochem J (2024) 481 (20): 1379–1393.
https://doi.org/10.1042/BCJ20240366
Published: 07 October 2024
View articletitled, Revamped role for approved drug: integrative computational and biophysical analysis of saquinavir's peptidyl arginine deiminase 4 inhibition for rheumatoid arthritis
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Includes: Supplementary data
Articles

CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation

Paul A. O'Sullivan, Aigerim Aidarova, Inna S. Afonina, Joan Manils, Teresa L. M. Thurston, Rachael Instrell, Michael Howell, Stefan Boeing, Sashini Ranawana, Melanie B. Herpels, Riwia Chetian, Matilda Bassa, Helen Flynn, David Frith, Ambrosius P. Snijders, Ashleigh Howes, Rudi Beyaert, Anne M. Bowcock, Steven C. Ley
Journal: Biochemical Journal
Biochem J (2024) 481 (18): 1143–1171.
https://doi.org/10.1042/BCJ20240058
Published: 06 September 2024
View articletitled, CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation
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Includes: Supplementary data
Articles

Inducible gene expression of IκB-kinase ε is dependent on nuclear factor-κB in human pulmonary epithelial cells

Amandah Necker-Brown, Cora Kooi, Andrew J. Thorne, Akanksha Bansal, Mahmoud M. Mostafa, Priyanka Chandramohan, Alex Gao, Keerthana Kalyanaraman, Arya Milani, Sachman Gill, Andrei Georgescu, Sarah K. Sasse, Anthony N. Gerber, Richard Leigh, Robert Newton
Journal: Biochemical Journal
Biochem J (2024) 481 (14): 959–980.
https://doi.org/10.1042/BCJ20230461
Published: 12 July 2024
View articletitled, Inducible gene expression of IκB-kinase ε is dependent on nuclear factor-κB in human pulmonary epithelial cells
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Includes: Supplementary data
Articles

IL-4 activates the futile triacylglyceride cycle for glucose utilization in white adipocytes

Svetlana Michurina, Margarita Agareva, Ekaterina Zubkova, Mikhail Menshikov, Iurii Stafeev, Yelena Parfyonova
Journal: Biochemical Journal
Biochem J (2024) 481 (4): 329–344.
https://doi.org/10.1042/BCJ20230486
Published: 19 February 2024
View articletitled, IL-4 activates the futile triacylglyceride cycle for glucose utilization in white adipocytes
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Includes: Supplementary data
Articles

Identification of a 10-mer peptide from the death domain of MyD88 which attenuates inflammation and insulin resistance and improves glucose metabolism

Mehmood Ali, Tripti Kumari, Arvind Gupta, Sariyah Akhtar, Rahul Dev Verma, Jimut Kanti Ghosh
Journal: Biochemical Journal
Biochem J (2024) 481 (4): 191–218.
https://doi.org/10.1042/BCJ20230369
Published: 13 February 2024
View articletitled, Identification of a 10-mer peptide from the death domain of MyD88 which attenuates inflammation and insulin resistance and improves glucose metabolism
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Includes: Supplementary data
Articles

Understanding interleukin 11 as a disease gene and therapeutic target

Stuart A. Cook
Journal: Biochemical Journal
Biochem J (2023) 480 (23): 1987–2008.
https://doi.org/10.1042/BCJ20220160
Published: 06 December 2023
View articletitled, Understanding interleukin 11 as a disease gene and therapeutic target
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Articles

Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?

Douglas B. Kell, Etheresia Pretorius
Journal: Biochemical Journal
Biochem J (2023) 480 (15): 1217–1240.
https://doi.org/10.1042/BCJ20230241
Published: 16 August 2023
View articletitled, Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?
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Articles

Protein targeting by the itaconate family in immunity and inflammation

Emily A. Day, Luke A.J. O'Neill
Journal: Biochemical Journal
Biochem J (2022) 479 (24): 2499–2510.
https://doi.org/10.1042/BCJ20220364
Published: 22 December 2022
View articletitled, Protein targeting by the itaconate family in immunity and inflammation
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Articles

Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12

Elisha H. McCrory, Vyacheslav Akimov, Philip Cohen, Blagoy Blagoev
Journal: Biochemical Journal
Biochem J (2022) 479 (23): 2419–2431.
https://doi.org/10.1042/BCJ20220510
Published: 07 December 2022
View articletitled, Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12
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Includes: Supplementary data
Articles

Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development

Qian Wei, Kjetil Taskén
Journal: Biochemical Journal
Biochem J (2022) 479 (20): 2219–2260.
https://doi.org/10.1042/BCJ20210233
Published: 28 October 2022
View articletitled, Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development
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Articles

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte, Philip Cohen
Journal: Biochemical Journal
Biochem J (2022) 479 (20): 2195–2216.
https://doi.org/10.1042/BCJ20220401
Published: 21 October 2022
View articletitled, Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC
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Includes: Supplementary data
Articles

Mechanisms of TNF-independent RIPK3-mediated cell death

Bart Tummers, Douglas R. Green
Journal: Biochemical Journal
Biochem J (2022) 479 (19): 2049–2062.
https://doi.org/10.1042/BCJ20210724
Published: 14 October 2022
View articletitled, Mechanisms of TNF-independent RIPK3-mediated cell death
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Articles

TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells

Melissa Rodrigues, Tsvetana Petrova, Brendan Tibbs, J. Simon C. Arthur, Philip Cohen
Journal: Biochemical Journal
Biochem J (2022) 479 (17): 1891–1907.
https://doi.org/10.1042/BCJ20220314
Published: 16 September 2022
View articletitled, TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells
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Includes: Supplementary data
Articles

Cell death in skin function, inflammation, and disease

In Collection
Cell death and survival
Holly Anderton, Suhaib Alqudah
Journal: Biochemical Journal
Biochem J (2022) 479 (15): 1621–1651.
https://doi.org/10.1042/BCJ20210606
Published: 05 August 2022
View articletitled, Cell death in skin function, inflammation, and disease
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Articles

Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4 + T-cell proliferation and glycolytic activity under hypoxia and normoxia

Jonas A. Wik, Azazul Chowdhury, Shrikant Kolan, Nasser E. Bastani, Gaoyang Li, Kazi Alam, Franco Grimolizzi, Bjørn S. Skålhegg
Journal: Biochemical Journal
Biochem J (2022) 479 (11): 1221–1235.
https://doi.org/10.1042/BCJ20220144
Published: 13 June 2022
View articletitled, Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4 + T-cell proliferation and glycolytic activity under hypoxia and normoxia
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Includes: Supplementary data
Articles

No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death

In Collection
Cell death and survival
Ashley Weir, James E. Vince
Journal: Biochemical Journal
Biochem J (2022) 479 (10): 1083–1102.
https://doi.org/10.1042/BCJ20210711
Published: 24 May 2022
View articletitled, No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death
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Articles

Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo

Sandra Wymann, Marcel Mischnik, David Leong, Subhajit Ghosh, Xiahui Tan, Helen Cao, Benjamin Kuehnemuth, Glenn A. Powers, Partho Halder, Mitchell J. de Souza, Hannah S. James, Vesna Tomasetig, Holger Lind, Paolo Rossato, Catherine M. Owczarek, Saw Yen Ow, Steven K. Dower, Adriana Baz Morelli, Tony Rowe, Matthew P. Hardy
Journal: Biochemical Journal
Biochem J (2022) 479 (9): 1007–1030.
https://doi.org/10.1042/BCJ20220054
Published: 13 May 2022
View articletitled, Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo
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Includes: Supplementary data
Articles

RIP1 post-translational modifications

In Collection
Cell death and survival
Eugene Varfolomeev, Domagoj Vucic
Journal: Biochemical Journal
Biochem J (2022) 479 (9): 929–951.
https://doi.org/10.1042/BCJ20210725
Published: 06 May 2022
View articletitled, RIP1 post-translational modifications
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Articles

Activation and manipulation of inflammasomes and pyroptosis during bacterial infections

In Collection
Cell death and survival
Elliott M. Bernard, Petr Broz
Journal: Biochemical Journal
Biochem J (2022) 479 (7): 867–882.
https://doi.org/10.1042/BCJ20220051
Published: 19 April 2022
View articletitled, Activation and manipulation of inflammasomes and pyroptosis during bacterial infections
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Articles

Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants

Tristram A. J. Ryan, Roger J. S. Preston, Luke A. J. O'Neill
Journal: Biochemical Journal
Biochem J (2022) 479 (6): 731–750.
https://doi.org/10.1042/BCJ20210522
Published: 28 March 2022
View articletitled, Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants
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Articles

Regulation of the release of damage-associated molecular patterns from necroptotic cells

In Collection
Cell death and survival
Hiroyasu Nakano, Shin Murai, Kenta Moriwaki
Journal: Biochemical Journal
Biochem J (2022) 479 (5): 677–685.
https://doi.org/10.1042/BCJ20210604
Published: 16 March 2022
View articletitled, Regulation of the release of damage-associated molecular patterns from necroptotic cells
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Includes: Supplementary data
Articles

Programmed cell death: the pathways to severe COVID-19?

In Collection
Cell death and survival , Coronavirus
Stefanie M. Bader, James P. Cooney, Marc Pellegrini, Marcel Doerflinger
Journal: Biochemical Journal
Biochem J (2022) 479 (5): 609–628.
https://doi.org/10.1042/BCJ20210602
Published: 04 March 2022
View articletitled, Programmed cell death: the pathways to severe COVID-19?
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Articles

A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications

In Collection
Coronavirus
Douglas B. Kell, Gert Jacobus Laubscher, Etheresia Pretorius
Journal: Biochemical Journal
Biochem J (2022) 479 (4): 537–559.
https://doi.org/10.1042/BCJ20220016
Published: 23 February 2022
View articletitled, A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications
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Articles

Adaptor protein 3BP2 regulates dectin-1-mediated cellular signalling to induce cytokine expression and NF-κB activation

Kazuyasu Chihara, Yuri Chihara, Kenji Takeuchi, Kiyonao Sada
Journal: Biochemical Journal
Biochem J (2022) 479 (4): 503–523.
https://doi.org/10.1042/BCJ20210707
Published: 23 February 2022
View articletitled, Adaptor protein 3BP2 regulates dectin-1-mediated cellular signalling to induce cytokine expression and NF-κB activation
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Includes: Supplementary data
Articles

Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation

Rayner M. L. Queiroz, Siân C. Piper, Johanna S. Rees, Sam Strickson, Emmanuel Briend, Choon Pei Low, G. John Ferguson, Kathryn S. Lilley, Antony P. Jackson, Donna K. Finch
Journal: Biochemical Journal
Biochem J (2022) 479 (3): 225–243.
https://doi.org/10.1042/BCJ20210313
Published: 04 February 2022
View articletitled, Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation
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Includes: Supplementary data
Articles

TAT–RHIM: a more complex issue than expected

In Collection
Cell death and survival
Benedikt Kolbrink, Theresa Riebeling, Nikolas K. Teiwes, Claudia Steinem, Hubert Kalbacher, Ulrich Kunzendorf, Stefan Krautwald
Journal: Biochemical Journal
Biochem J (2022) 479 (3): 259–272.
https://doi.org/10.1042/BCJ20210677
Published: 04 February 2022
View articletitled, TAT–RHIM: a more complex issue than expected
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Articles

IKKα plays a major role in canonical NF-κB signalling in colorectal cells

In Collection
Cell death and survival
Jack A. Prescott, Kathryn Balmanno, Jennifer P. Mitchell, Hanneke Okkenhaug, Simon J. Cook
Journal: Biochemical Journal
Biochem J (2022) 479 (3): 305–325.
https://doi.org/10.1042/BCJ20210783
Published: 04 February 2022
View articletitled, IKKα plays a major role in canonical NF-κB signalling in colorectal cells
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Includes: Supplementary data
Articles

Systems approaches to investigate the role of NF-κB signaling in aging

In Collection
Towards systems biochemistry
Masatoshi Haga, Mariko Okada
Journal: Biochemical Journal
Biochem J (2022) 479 (2): 161–183.
https://doi.org/10.1042/BCJ20210547
Published: 28 January 2022
View articletitled, Systems approaches to investigate the role of NF-κB signaling in aging
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Articles

Mechanistic diversity in MHC class I antigen recognition

Camila R. R. Barbosa, Justin Barton, Adrian J. Shepherd, Michele Mishto
Journal: Biochemical Journal
Biochem J (2021) 478 (24): 4187–4202.
https://doi.org/10.1042/BCJ20200910
Published: 23 December 2021
View articletitled, Mechanistic diversity in MHC class I antigen recognition
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Articles

NAD + -consuming enzymes in immune defense against viral infection

Jialin Shang, Michael R. Smith, Ananya Anmangandla, Hening Lin
Journal: Biochemical Journal
Biochem J (2021) 478 (23): 4071–4092.
https://doi.org/10.1042/BCJ20210181
Published: 06 December 2021
View articletitled, NAD + -consuming enzymes in immune defense against viral infection
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Articles

Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: involvement of IFNγ-JAK2-STAT1 pathway

Dipanjan Chattopadhyay, Snehasis Das, Suktara Guria, Soumyadeep Basu, Sutapa Mukherjee
Journal: Biochemical Journal
Biochem J (2021) 478 (22): 4027–4043.
https://doi.org/10.1042/BCJ20210442
Published: 26 November 2021
View articletitled, Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: involvement of IFNγ-JAK2-STAT1 pathway
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Includes: Supplementary data
Articles

Regulation of Tim-3 function by binding to phosphatidylserine

Lawrence P. Kane
Journal: Biochemical Journal
Biochem J (2021) 478 (22): 3999–4004.
https://doi.org/10.1042/BCJ20210652
Published: 23 November 2021
View articletitled, Regulation of Tim-3 function by binding to phosphatidylserine
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Articles

Phosphatidylserine binding directly regulates TIM-3 function

Courtney M. Smith, Alice Li, Nithya Krishnamurthy, Mark A. Lemmon
Journal: Biochemical Journal
Biochem J (2021) 478 (17): 3331–3349.
https://doi.org/10.1042/BCJ20210425
Published: 14 September 2021
View articletitled, Phosphatidylserine binding directly regulates TIM-3 function
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Includes: Supplementary data
Articles

Lactate cross-talk in host–pathogen interactions

Alba Llibre, Frances S. Grudzinska, Matthew K. O'Shea, Darragh Duffy, David R. Thickett, Claudio Mauro, Aaron Scott
Journal: Biochemical Journal
Biochem J (2021) 478 (17): 3157–3178.
https://doi.org/10.1042/BCJ20210263
Published: 07 September 2021
View articletitled, Lactate cross-talk in host–pathogen interactions
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Articles

TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells

Biserka Relic, Celine Deroyer, Olivier Malaise, Zelda Plener, Philippe Gillet, Dominique de Seny, Michel G. Malaise
Journal: Biochemical Journal
Biochem J (2021) 478 (16): 3145–3155.
https://doi.org/10.1042/BCJ20210174
Published: 27 August 2021
View articletitled, TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells
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Articles

Manipulating the exposome to enable better ageing

Paul G. Shiels, Johanna Painer, Barbara Natterson-Horowitz, Richard J. Johnson, Jaime J. Miranda, Peter Stenvinkel
Journal: Biochemical Journal
Biochem J (2021) 478 (14): 2889–2898.
https://doi.org/10.1042/BCJ20200958
Published: 28 July 2021
View articletitled, Manipulating the exposome to enable better ageing
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Articles

Importance of tyrosine phosphorylation for transmembrane signaling in plants

Henning Mühlenbeck, Kyle W. Bender, Cyril Zipfel
Journal: Biochemical Journal
Biochem J (2021) 478 (14): 2759–2774.
https://doi.org/10.1042/BCJ20210202
Published: 23 July 2021
View articletitled, Importance of tyrosine phosphorylation for transmembrane signaling in plants
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Articles

Inhibitory feedback control of NF-κB signalling in health and disease

Jack A. Prescott, Jennifer P. Mitchell, Simon J. Cook
Journal: Biochemical Journal
Biochem J (2021) 478 (13): 2619–2664.
https://doi.org/10.1042/BCJ20210139
Published: 16 July 2021
View articletitled, Inhibitory feedback control of NF-κB signalling in health and disease
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Articles

FATP4 inactivation in cultured macrophages attenuates M1- and ER stress-induced cytokine release via a metabolic shift towards triacylglycerides

Yuling Zhang, Ning Wu, Hongying Gan-Schreier, Feng Xu, Sabine Tuma-Kellner, Simone Staffer, Jessica Seeßle, Uta Merle, Walee Chamulitrat
Journal: Biochemical Journal
Biochem J (2021) 478 (10): 1861–1877.
https://doi.org/10.1042/BCJ20210155
Published: 18 May 2021
View articletitled, FATP4 inactivation in cultured macrophages attenuates M1- and ER stress-induced cytokine release via a metabolic shift towards triacylglycerides
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Includes: Supplementary data
Articles

Opposing forces fight over the same ground to regulate interferon signaling

William L. Blalock
Journal: Biochemical Journal
Biochem J (2021) 478 (10): 1853–1859.
https://doi.org/10.1042/BCJ20210110
Published: 18 May 2021
View articletitled, Opposing forces fight over the same ground to regulate interferon signaling
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Articles

Tick–human interactions: from allergic klendusity to the α-Gal syndrome

Alejandro Cabezas-Cruz, Adnan Hodžić, Lourdes Mateos-Hernández, Marinela Contreras, José de la Fuente
Journal: Biochemical Journal
Biochem J (2021) 478 (9): 1783–1794.
https://doi.org/10.1042/BCJ20200915
Published: 14 May 2021
View articletitled, Tick–human interactions: from allergic klendusity to the α-Gal syndrome
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Articles

Anti-glycan antibodies: roles in human disease

J. Sebastian Temme, Dorothy L. Butler, Jeffrey C. Gildersleeve
Journal: Biochemical Journal
Biochem J (2021) 478 (8): 1485–1509.
https://doi.org/10.1042/BCJ20200610
Published: 21 April 2021
View articletitled, Anti-glycan antibodies: roles in human disease
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Articles

T cells: a dedicated effector kinase pathways for every trait?

Kriti Bahl, Jeroen P. Roose
Journal: Biochemical Journal
Biochem J (2021) 478 (6): 1303–1307.
https://doi.org/10.1042/BCJ20210006
Published: 23 March 2021
View articletitled, T cells: a dedicated effector kinase pathways for every trait?
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Articles

Reprogramming the tumor metastasis cascade by targeting galectin-driven networks

Ramiro M. Perrotta, Camila A. Bach, Mariana Salatino, Gabriel A. Rabinovich
Journal: Biochemical Journal
Biochem J (2021) 478 (3): 597–617.
https://doi.org/10.1042/BCJ20200167
Published: 12 February 2021
View articletitled, Reprogramming the tumor metastasis cascade by targeting galectin-driven networks
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Articles

Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling

Lauren S. Vaughn, Evelyn Chukwurah, Rekha C. Patel
Journal: Biochemical Journal
Biochem J (2021) 478 (3): 493–510.
https://doi.org/10.1042/BCJ20200987
Published: 05 February 2021
View articletitled, Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling
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