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Articles
Investigating the differential structural organization and gene expression regulatory networks of lamin A Ig fold domain mutants of muscular dystrophy
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2024) 481 (23): 1803–1827.
Published: 28 November 2024
Includes: Supplementary data
Articles
Articles
Articles
Articles
Maria A. Voronkova, Heather L. Hansen, Madison P. Cooper, Jacob Miller, Narayanasami Sukumar, Werner J. Geldenhuys, Aaron R. Robart, Bradley A. Webb
Journal:
Biochemical Journal
Biochem J (2023) 480 (17): 1411–1427.
Published: 04 September 2023
Includes: Supplementary data
Articles
RyR2 C-terminal truncating variants identified in patients with arrhythmic phenotypes exert a dominant negative effect through formation of wildtype-truncation heteromers
Available to PurchaseShanshan Tian, Xiaowei Zhong, Hui Wang, Jinhong Wei, Wenting Guo, Ruiwu Wang, John Paul Estillore, Carlo Napolitano, Henry H. Duff, Erkan Ilhan, Linda M. Knight, Michael S. Lloyd, Jason D. Roberts, Silvia G. Priori, S.R. Wayne Chen
Journal:
Biochemical Journal
Biochem J (2023) 480 (17): 1379–1395.
Published: 01 September 2023
Articles
Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration
Open AccessIn Collection
Cell signaling in the 21st century
Alexander C. Jones, Alexandr P. Kornev, Jui-Hung Weng, Gerard Manning, Susan S. Taylor, Alexandra C. Newton
Journal:
Biochemical Journal
Biochem J (2023) 480 (16): 1299–1316.
Published: 25 August 2023
Includes: Supplementary data
Articles
Inherited disease-linked arginine76/75 mutants in Cx50 and Cx45 showed impaired homotypic and heterotypic gap junction function, but not Cx43
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2023) 480 (14): 1051–1077.
Published: 17 July 2023
Articles
Classification of Cushing's syndrome PKAc mutants based upon their ability to bind PKI
Available to PurchaseIn Collection
Cell signaling in the 21st century
Mitchell H. Omar, Maryanne Kihiu, Dominic P. Byrne, Kyung-Soon Lee, Tyler M. Lakey, Erik Butcher, Patrick A. Eyers, John D. Scott
Journal:
Biochemical Journal
Biochem J (2023) 480 (12): 875–890.
Published: 22 June 2023
Articles
Key allosteric and active site residues of SARS-CoV-2 3CLpro are promising drug targets
Available to PurchaseIn Collection
Tackling SARS-CoV-2 biochemistry
Journal:
Biochemical Journal
Biochem J (2023) 480 (11): 791–813.
Published: 07 June 2023
Includes: Supplementary data
Articles
Mutagenic incorporation of inosine into DNA via T:I mismatch formation by human DNA polymerase eta (polη)
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2023) 480 (9): 649–664.
Published: 10 May 2023
Articles
Genotoxic effects of the major alkylation damage N7-methylguanine and methyl formamidopyrimidine
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2023) 480 (9): 573–585.
Published: 04 May 2023
Articles
Genome damage accumulated in seed ageing leads to plant genome instability and growth inhibition
Open Access
Journal:
Biochemical Journal
Biochem J (2023) 480 (7): 461–470.
Published: 04 April 2023
Articles
The C-terminal region of phytoene synthase is a key element to control carotenoid biosynthesis in the haloarchaeon Haloferax volcanii
Available to PurchaseMicaela Cerletti, Agustín Rabino, Roberto A. Paggi, Celeste Ferrari, Ansgar Poetsch, Harri Savilahti, Saija Kiljunen, Rosana E. De Castro
Journal:
Biochemical Journal
Biochem J (2022) 479 (22): 2365–2377.
Published: 23 November 2022
Includes: Supplementary data
Articles
Structure of the major oxidative damage 7,8-dihydro-8-oxoguanine presented into a catalytically competent DNA glycosylase
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2022) 479 (21): 2297–2309.
Published: 04 November 2022
Articles
Effect of α-helical domain of Gi/o α subunit on GDP/GTP turnover
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2022) 479 (17): 1843–1855.
Published: 12 September 2022
Includes: Supplementary data
Articles
Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes
Open AccessEmily L. Button, Joseph J. Rossi, Daniel P. McDougal, John B. Bruning, Daniel J. Peet, David C. Bersten, Jill A. Rosenfeld, Murray L. Whitelaw
Journal:
Biochemical Journal
Biochem J (2022) 479 (13): 1441–1454.
Published: 13 July 2022
Includes: Supplementary data
Articles
Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system
Available to PurchaseJohanna Maarit Koivisto, Nina Rødtness Poulsen, Benedikte Stoklund Larsen, M.G.M. Weibull, Amelie Stein, Fabio Doro, Jakob Rahr Winther, Kresten Lindorff-Larsen, Martin Willemoës
Journal:
Biochemical Journal
Biochem J (2022) 479 (4): 479–501.
Published: 17 February 2022
Includes: Supplementary data
Articles
Conserved L464 in p97 D1–D2 linker is critical for p97 cofactor regulated ATPase activity
Available to PurchaseXiaoyi Zhang, Lin Gui, Shan Li, Purbasha Nandi, Rod Carlo Columbres, Daniel E. Wong, Derek R. Moen, Henry J. Lin, Po-Lin Chiu, Tsui-Fen Chou
Journal:
Biochemical Journal
Biochem J (2021) 478 (17): 3185–3204.
Published: 07 September 2021
Includes: Supplementary data
Articles
Articles
Articles
Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (9): 1769–1781.
Published: 10 May 2021
Articles
Unusual ring D fixation by three crucial residues promotes phycoviolobilin formation in the DXCF-type cyanobacteriochrome without the second Cys
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2021) 478 (5): 1043–1059.
Published: 04 March 2021
Includes: Supplementary data
Articles
A conserved, buried cysteine near the P-site is accessible to cysteine modifications and increases ROS stability in the P-type plasma membrane H + -ATPase
Available to PurchaseMarcel Welle, Jesper T. Pedersen, Tina Ravnsborg, Maki Hayashi, Sandra Maaß, Dörte Becher, Ole N. Jensen, Christine Stöhr, Michael Palmgren
Journal:
Biochemical Journal
Biochem J (2021) 478 (3): 619–632.
Published: 12 February 2021
Includes: Supplementary data
Articles
Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity
Available to PurchaseMatthias Fellner, Rinky Parakra, Kirstin O. McDonald, Itamar Kass, Guy N.L. Jameson, Sigurd M. Wilbanks, Elizabeth C. Ledgerwood
Journal:
Biochemical Journal
Biochem J (2021) 478 (3): 669–684.
Published: 12 February 2021
Includes: Supplementary data
Articles
Loss of cell wall integrity genes cpxA and mrcB causes flocculation in Escherichia coli
Available to PurchaseKeita Sugawara, Hayato Toyoda, Mami Kimura, Shunsuke Hayasaka, Hiromi Saito, Hiroshi Kobayashi, Kunio Ihara, Tomoaki Ida, Takaaki Akaike, Eiji Ando, Mamoru Hyodo, Yoshihiro Hayakawa, Shin Hamamoto, Nobuyuki Uozumi
Journal:
Biochemical Journal
Biochem J (2021) 478 (1): 41–59.
Published: 08 January 2021
Articles
Structural insights into the bypass of the major deaminated purines by translesion synthesis DNA polymerase
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (24): 4797–4810.
Published: 24 December 2020
Articles
Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate
Available to PurchaseBibek Parajuli, Kriti Acharya, Aakansha Nangarlia, Shiyu Zhang, Bijay Parajuli, Alexej Dick, Brendon Ngo, Cameron F. Abrams, Irwin Chaiken
Journal:
Biochemical Journal
Biochem J (2020) 477 (21): 4263–4280.
Published: 13 November 2020
Includes: Supplementary data
Articles
Transporter tandems: precise tools for normalizing active transporter in the plasma membrane
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (21): 4191–4206.
Published: 09 November 2020
Includes: Supplementary data
Articles
Znc2 module of RAG1 contributes towards structure-specific nuclease activity of RAGs
Available to PurchaseNamrata M. Nilavar, Mayilaadumveettil Nishana, Amita M. Paranjape, Raghunandan Mahadeva, Rupa Kumari, Bibha Choudhary, Sathees C. Raghavan
Journal:
Biochemical Journal
Biochem J (2020) 477 (18): 3567–3582.
Published: 24 September 2020
Articles
An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity
Available to PurchaseLucas A. Luna, Zachary Lesecq, Katharine A. White, An Hoang, David A. Scott, Olga Zagnitko, Andrey A. Bobkov, Diane L. Barber, Jamie M. Schiffer, Daniel G. Isom, Christal D. Sohl
Journal:
Biochemical Journal
Biochem J (2020) 477 (16): 2999–3018.
Published: 21 August 2020
Includes: Supplementary data
Articles
Establishment and characterization of Neu1-knockout zebrafish and its abnormal clinical phenotypes
Available to PurchaseKeiji Okada, Ryo Takase, Yurie Hamaoka, Akinobu Honda, Asami Ikeda, Yoichiro Hokazono, Yutaro Maeda, Oki Hayasaka, Tomonari Kotani, Masaharu Komatsu, Kazuhiro Shiozaki
Journal:
Biochemical Journal
Biochem J (2020) 477 (15): 2841–2857.
Published: 12 August 2020
Includes: Supplementary data
Articles
Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (15): 2859–2871.
Published: 12 August 2020
Articles
DNA-damage tolerance through PCNA ubiquitination and sumoylation
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (14): 2655–2677.
Published: 29 July 2020
Articles
Characterization of a naturally occurring mutation V368M in the human glucagon receptor and its association with metabolic disorders
Available to PurchaseGuangyao Lin, Qiaofeng Liu, Antao Dai, Xiaoqing Cai, Qingtong Zhou, Xi Wang, Yan Chen, Chenyu Ye, Jie Li, Dehua Yang, Ming-Wei Wang
Journal:
Biochemical Journal
Biochem J (2020) 477 (13): 2581–2594.
Published: 17 July 2020
Includes: Supplementary data
Articles
Yannan Wang, Laurie A. Graham, Zhifu Han, Robert Eves, Audrey K. Gruneberg, Robert L. Campbell, Heqiao Zhang, Peter L. Davies
Journal:
Biochemical Journal
Biochem J (2020) 477 (12): 2179–2192.
Published: 22 June 2020
Includes: Multimedia, Supplementary data
Articles
Quantitative mapping of binding specificity landscapes for homologous targets by using a high-throughput method
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (9): 1701–1719.
Published: 11 May 2020
Includes: Supplementary data
Articles
Phosphatase-defective DevS sensor kinase mutants permit constitutive expression of DevR-regulated dormancy genes in Mycobacterium tuberculosis
Available to PurchasePriyanka Kumari, Sudhir Kumar, Kohinoor Kaur, Umesh Datta Gupta, Sameer Suresh Bhagyawant, Jaya Sivaswami Tyagi
Journal:
Biochemical Journal
Biochem J (2020) 477 (9): 1669–1682.
Published: 11 May 2020
Includes: Supplementary data
Articles
Molecular origins of folding rate differences in the thioredoxin family
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (6): 1083–1087.
Published: 18 March 2020
Articles
Plant organellar DNA polymerases bypass thymine glycol using two conserved lysine residues
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (5): 1049–1059.
Published: 13 March 2020
Includes: Supplementary data
Articles
Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (5): 937–951.
Published: 06 March 2020
Articles
Metal-induced change in catalytic loop positioning in Helicobacter pylori arginase alters catalytic function
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2019) 476 (23): 3595–3614.
Published: 10 December 2019
Includes: Supplementary data
Articles
An acetylation mimicking mutation, K274Q, in tau imparts neurotoxicity by enhancing tau aggregation and inhibiting tubulin polymerization
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2019) 476 (10): 1401–1417.
Published: 21 May 2019
Includes: Supplementary data
Articles
Discovery of natural product ovalicin sensitive type 1 methionine aminopeptidases: molecular and structural basis
Available to PurchaseVijaykumar Pillalamarri, Tarun Arya, Neshatul Haque, Sandeep Chowdary Bala, Anil Kumar Marapaka, Anthony Addlagatta
Journal:
Biochemical Journal
Biochem J (2019) 476 (6): 991–1003.
Published: 22 March 2019
Includes: Multimedia, Supplementary data
Articles
Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction
Available to PurchaseSahar I. Da'as, Khalid Fakhro, Angelos Thanassoulas, Navaneethakrishnan Krishnamoorthy, Alaaeldin Saleh, Brian L. Calver, Bared Safieh-Garabedian, Egon Toft, George Nounesis, F. Anthony Lai, Michail Nomikos
Journal:
Biochemical Journal
Biochem J (2018) 475 (24): 3933–3948.
Published: 14 December 2018
Includes: Supplementary data
Articles
Structural insights into the interaction of helicase and primase in Mycobacterium tuberculosis
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (21): 3493–3509.
Published: 15 November 2018
Includes: Supplementary data
Articles
Role of cysteine 416 in N -ethylmaleimide sensitivity of human equilibrative nucleoside transporter 1 (hENT1)
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (20): 3293–3309.
Published: 31 October 2018
Articles
Mutation of G51 in SepF impairs FtsZ assembly promoting ability of SepF and retards the division of Mycobacterium smegmatis cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (15): 2473–2489.
Published: 14 August 2018
Includes: Supplementary data
Articles
Crystal structure and pH-dependent allosteric regulation of human β-ureidopropionase, an enzyme involved in anticancer drug metabolism
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (14): 2395–2416.
Published: 31 July 2018
Includes: Supplementary data
Articles
Structural insights into lethal contractural syndrome type 3 (LCCS3) caused by a missense mutation of PIP5Kγ
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2018) 475 (14): 2257–2269.
Published: 25 July 2018
Includes: Supplementary data
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