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Articles

The genetic and molecular basis of a connexin-linked skin disease

Sergiu A. Lucaciu, Dale W. Laird

Biochem J (2024) 481 (22): 1639–1655.

https://doi.org/10.1042/BCJ20240374

Published: 08 November 2024

View article titled, The genetic and molecular basis of a connexin-linked skin disease

Articles

Advances in the cell biology of the trafficking and processing of amyloid precursor protein: impact of familial Alzheimer's disease mutations

Jingqi Wang, Lou Fourriere, Paul A. Gleeson

Biochem J (2024) 481 (19): 1297–1325.

https://doi.org/10.1042/BCJ20240056

Published: 20 September 2024

View article titled, Advances in the cell biology of the trafficking and processing of amyloid precursor protein: impact of familial Alzheimer's disease mutations

Articles

Evolution and maintenance of mtDNA gene content across eukaryotes

Shibani Veeraragavan, Maria Johansen, Iain G. Johnston

Biochem J (2024) 481 (15): 1015–1042.

https://doi.org/10.1042/BCJ20230415

Published: 05 August 2024

View article titled, Evolution and maintenance of mtDNA gene content across eukaryotes

Includes: Supplementary data

Articles

Mechanisms and pathologies of human mitochondrial DNA replication and deletion formation

Tiago M. Bernardino Gomes, Amy E. Vincent, Katja E. Menger, James B. Stewart, Thomas J. Nicholls

Biochem J (2024) 481 (11): 683–715.

https://doi.org/10.1042/BCJ20230262

Published: 28 May 2024

View article titled, Mechanisms and pathologies of human mitochondrial DNA replication and deletion formation

Articles

The role of mitochondrial RNA association for mitochondrial homeostasis in neurons

Inmaculada Segura, Angelika Harbauer

Biochem J (2024) 481 (3): 119–139.

https://doi.org/10.1042/BCJ20230110

Published: 29 January 2024

View article titled, The role of mitochondrial RNA association for mitochondrial homeostasis in neurons

Articles

Fluorescent biosensors illuminate the spatial regulation of cell signaling across scales

In Collection

Cell signaling in the 21st century

Anne C. Lyons, Sohum Mehta, Jin Zhang

Biochem J (2023) 480 (20): 1693–1717.

https://doi.org/10.1042/BCJ20220223

Published: 30 October 2023

View article titled, Fluorescent biosensors illuminate the spatial regulation of cell signaling across scales

Articles

Mitophagy in yeast: known unknowns and unknown unknowns

Hagai Abeliovich

Biochem J (2023) 480 (20): 1639–1657.

https://doi.org/10.1042/BCJ20230279

Published: 18 October 2023

View article titled, Mitophagy in yeast: known unknowns and unknown unknowns

Articles

Seasonal cold induces divergent structural/biochemical adaptations in different skeletal muscles of Columba livia : evidence for nonshivering thermogenesis in adult birds

Punyadhara Pani, Gourabamani Swalsingh, Sunil Pani, Unmod Senapati, Bijayashree Sahu, Benudhara Pati, Subhasmita Rout, Naresh C. Bal

Biochem J (2023) 480 (17): 1397–1409.

https://doi.org/10.1042/BCJ20230245

Published: 04 September 2023

View article titled, Seasonal cold induces divergent structural/biochemical adaptations in different skeletal muscles of Columba livia : evidence for nonshivering thermogenesis in adult birds

Includes: Supplementary data

Articles

The biochemistry and physiology of long-chain dicarboxylic acid metabolism

Pablo Ranea-Robles, Sander M. Houten

Biochem J (2023) 480 (9): 607–627.

https://doi.org/10.1042/BCJ20230041

Published: 04 May 2023

View article titled, The biochemistry and physiology of long-chain dicarboxylic acid metabolism

Articles

Macropinocytosis: mechanisms and regulation

Gilbert Salloum, Anne R. Bresnick, Jonathan M. Backer

Biochem J (2023) 480 (5): 335–362.

https://doi.org/10.1042/BCJ20210584

Published: 15 March 2023

View article titled, Macropinocytosis: mechanisms and regulation

Includes: Multimedia, Supplementary data

Articles

Structural and functional organization of germ plasm condensates

Austin Chiappetta, Jeffrey Liao, Siran Tian, Tatjana Trcek

Biochem J (2022) 479 (24): 2477–2495.

https://doi.org/10.1042/BCJ20210815

Published: 19 December 2022

View article titled, Structural and functional organization of germ plasm condensates

Articles

PI(4,5)P 2 : signaling the plasma membrane

Rachel C. Wills, Gerald R. V. Hammond

Biochem J (2022) 479 (21): 2311–2325.

https://doi.org/10.1042/BCJ20220445

Published: 11 November 2022

View article titled, PI(4,5)P 2 : signaling the plasma membrane

Articles

Proteomic mapping and optogenetic manipulation of membrane contact sites

Gang Lin, Wenyi Shi, Ningxia Zhang, Yi-Tsang Lee, Youjun Wang, Ji Jing

Biochem J (2022) 479 (17): 1857–1875.

https://doi.org/10.1042/BCJ20220382

Published: 16 September 2022

View article titled, Proteomic mapping and optogenetic manipulation of membrane contact sites

Articles

FoxO transcription factors in mitochondrial homeostasis

Zhiyong Cheng

Biochem J (2022) 479 (4): 525–536.

https://doi.org/10.1042/BCJ20210777

Published: 23 February 2022

View article titled, FoxO transcription factors in mitochondrial homeostasis

Articles

SNARE proteins: zip codes in vesicle targeting?

Seiichi Koike, Reinhard Jahn

Biochem J (2022) 479 (3): 273–288.

https://doi.org/10.1042/BCJ20210719

Published: 04 February 2022

View article titled, SNARE proteins: zip codes in vesicle targeting?

Articles

The complex interplay between autophagy and cell death pathways

In Collection

Cell death and survival

Christina Ploumi, Margarita-Elena Papandreou, Nektarios Tavernarakis

Biochem J (2022) 479 (1): 75–90.

https://doi.org/10.1042/BCJ20210450

Published: 14 January 2022

View article titled, The complex interplay between autophagy and cell death pathways

Articles

SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain

Patrick G. Needham, Jennifer L. Goeckeler-Fried, Casey Zhang, Zhihao Sun, Adam R. Wetzel, Carol A. Bertrand, Jeffrey L. Brodsky

Biochem J (2021) 478 (24): 4203–4220.

https://doi.org/10.1042/BCJ20210644

Published: 23 December 2021

View article titled, SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain

Includes: Supplementary data

Articles

Molecular mechanisms of mammalian autophagy

Charles B. Trelford, Gianni M. Di Guglielmo

Biochem J (2021) 478 (18): 3395–3421.

https://doi.org/10.1042/BCJ20210314

Published: 23 September 2021

View article titled, Molecular mechanisms of mammalian autophagy

Articles

Evolutionary rate covariation identifies SLC30A9 (ZnT9) as a mitochondrial zinc transporter

Amanda Kowalczyk, Omotola Gbadamosi, Kathryn Kolor, Jahree Sosa, Livia Andrzejczuk, Gregory Gibson, Claudette St Croix, Maria Chikina, Elias Aizenman, Nathan Clark, Kirill Kiselyov

Biochem J (2021) 478 (17): 3205–3220.

https://doi.org/10.1042/BCJ20210342

Published: 07 September 2021

View article titled, Evolutionary rate covariation identifies SLC30A9 (ZnT9) as a mitochondrial zinc transporter

Includes: Supplementary data

Articles

Quality control of protein import into mitochondria

Fabian den Brave, Jeannine Engelke, Thomas Becker

Biochem J (2021) 478 (16): 3125–3143.

https://doi.org/10.1042/BCJ20190584

Published: 26 August 2021

View article titled, Quality control of protein import into mitochondria

Articles

PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies

Susan S. Taylor, Maximilian Wallbott, Erik M. F. Machal, Kristoffer Søberg, Faihaa Ahmed, Jessica Bruystens, Lily Vu, Blaine Baker, Jian Wu, Francesco Raimondi, Elimelda M. Ongeri, Friedrich W. Herberg, Bjørn S. Skålhegg

Biochem J (2021) 478 (11): 2101–2119.

https://doi.org/10.1042/BCJ20200867

Published: 11 June 2021

View article titled, PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies

Includes: Multimedia, Supplementary data

Articles

Plasmodium falciparum Atg18 localizes to the food vacuole via interaction with the multi-drug resistance protein 1 and phosphatidylinositol 3-phosphate

Renu Sudhakar, Divya Das, Subramanian Thanumalayan, Somesh Gorde, Puran Singh Sijwali

Biochem J (2021) 478 (9): 1705–1732.

https://doi.org/10.1042/BCJ20210001

Published: 10 May 2021

View article titled, Plasmodium falciparum Atg18 localizes to the food vacuole via interaction with the multi-drug resistance protein 1 and phosphatidylinositol 3-phosphate

Includes: Supplementary data

Articles

FoxA2 and RNA Pol II mediate human islet amyloid polypeptide turnover in ER-stressed pancreatic β-cells

Diti Chatterjee Bhowmick, Lydia Burnett, Zhanar Kudaibergenova, Aleksandar M. Jeremic

Biochem J (2021) 478 (6): 1261–1282.

https://doi.org/10.1042/BCJ20200984

Published: 19 March 2021

View article titled, FoxA2 and RNA Pol II mediate human islet amyloid polypeptide turnover in ER-stressed pancreatic β-cells

Includes: Multimedia, Supplementary data

Articles

Phase transition of fibrillarin LC domain regulates localization and protein interaction of fibrillarin

Eunji Kim, Ilmin Kwon

Biochem J (2021) 478 (4): 799–810.

https://doi.org/10.1042/BCJ20200847

Published: 24 February 2021

View article titled, Phase transition of fibrillarin LC domain regulates localization and protein interaction of fibrillarin

Includes: Supplementary data

Articles

Nutrient transceptors physically interact with the yeast S6/protein kinase B homolog, Sch9, a TOR kinase target

Zhiqiang Zhang, Ines Cottignie, Griet Van Zeebroeck, Johan M. Thevelein

Biochem J (2021) 478 (2): 357–375.

https://doi.org/10.1042/BCJ20200722

Published: 27 January 2021

View article titled, Nutrient transceptors physically interact with the yeast S6/protein kinase B homolog, Sch9, a TOR kinase target

Includes: Supplementary data

Articles

Abnormal sterol-induced cell wall glucan deficiency in yeast is due to impaired glucan synthase transport to the plasma membrane

L. Roxana Gutierrez-Armijos, Rodrigo A. C. Sussmann, Ariel M. Silber, Mauro Cortez, Agustín Hernández

Biochem J (2020) 477 (24): 4729–4744.

https://doi.org/10.1042/BCJ20200663

Published: 18 December 2020

View article titled, Abnormal sterol-induced cell wall glucan deficiency in yeast is due to impaired glucan synthase transport to the plasma membrane

Includes: Supplementary data

Articles

Amino acid starvation inhibits autophagy in lipid droplet-deficient cells through mitochondrial dysfunction

Pierre Voisin, Marianne Bernard, Thierry Bergès, Matthieu Régnacq

Biochem J (2020) 477 (18): 3613–3623.

https://doi.org/10.1042/BCJ20200551

Published: 28 September 2020

View article titled, Amino acid starvation inhibits autophagy in lipid droplet-deficient cells through mitochondrial dysfunction

Includes: Supplementary data

Articles

Phosphoinositide lipids in primary cilia biology

Sarah E. Conduit, Bart Vanhaesebroeck

Biochem J (2020) 477 (18): 3541–3565.

https://doi.org/10.1042/BCJ20200277

Published: 24 September 2020

View article titled, Phosphoinositide lipids in primary cilia biology

Articles

Mitochondrial control of cellular protein homeostasis

Karthik Mohanraj, Urszula Nowicka, Agnieszka Chacinska

Biochem J (2020) 477 (16): 3033–3054.

https://doi.org/10.1042/BCJ20190654

Published: 26 August 2020

View article titled, Mitochondrial control of cellular protein homeostasis

Articles

Cytoskeleton regulators CAPZA2 and INF2 associate with CFTR to control its plasma membrane levels under EPAC1 activation

João D. Santos, Francisco R. Pinto, João F. Ferreira, Margarida D. Amaral, Manuela Zaccolo, Carlos M. Farinha

Biochem J (2020) 477 (13): 2561–2580.

https://doi.org/10.1042/BCJ20200287

Published: 10 July 2020

View article titled, Cytoskeleton regulators CAPZA2 and INF2 associate with CFTR to control its plasma membrane levels under EPAC1 activation

Includes: Supplementary data

Articles

Cell-penetrating peptides: two faces of the same coin

Giovanna Maria Pierantoni, Simona Paladino

Biochem J (2020) 477 (8): 1363–1366.

https://doi.org/10.1042/BCJ20200006

Published: 23 April 2020

View article titled, Cell-penetrating peptides: two faces of the same coin

Articles

EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

N.G. Eissa, E.J. Sayers, D. Birch, S.G. Patel, Y.-H. Tsai, H. Mørck Nielsen, A.T. Jones

Biochem J (2020) 477 (1): 45–60.

https://doi.org/10.1042/BCJ20190452

Published: 08 January 2020

View article titled, EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

Includes: Multimedia, Supplementary data

Articles

Into the basket and beyond: the journey of mRNA through the nuclear pore complex

Asaf Ashkenazy-Titelman, Yaron Shav-Tal, Ralph H. Kehlenbach

Biochem J (2020) 477 (1): 23–44.

https://doi.org/10.1042/BCJ20190132

Published: 08 January 2020

View article titled, Into the basket and beyond: the journey of mRNA through the nuclear pore complex

Articles

TMCC3 localizes at the three-way junctions for the proper tubular network of the endoplasmic reticulum

Sindhu Wisesa, Yasunori Yamamoto, Toshiaki Sakisaka

Biochem J (2019) 476 (21): 3241–3260.

https://doi.org/10.1042/BCJ20190359

Published: 11 November 2019

View article titled, TMCC3 localizes at the three-way junctions for the proper tubular network of the endoplasmic reticulum

Includes: Supplementary data

Articles

The Great Escape: how phosphatidylinositol 4-kinases and PI4P promote vesicle exit from the Golgi (and drive cancer)

Mark G. Waugh

Biochem J (2019) 476 (16): 2321–2346.

https://doi.org/10.1042/BCJ20180622

Published: 28 August 2019

View article titled, The Great Escape: how phosphatidylinositol 4-kinases and PI4P promote vesicle exit from the Golgi (and drive cancer)

Articles

Chloroplast thioredoxin systems dynamically regulate photosynthesis in plants

In Collection

Photosynthesis

Lauri Nikkanen, Eevi Rintamäki

Biochem J (2019) 476 (7): 1159–1172.

https://doi.org/10.1042/BCJ20180707

Published: 15 April 2019

View article titled, Chloroplast thioredoxin systems dynamically regulate photosynthesis in plants

Articles

New insights into niclosamide action: autophagy activation in colorectal cancer

Phillip T. Newton

Biochem J (2019) 476 (5): 779–781.

https://doi.org/10.1042/BCJ20190020

Published: 06 March 2019

View article titled, New insights into niclosamide action: autophagy activation in colorectal cancer

Articles

Solution structure of TbCentrin4 from Trypanosoma brucei and its interactions with Ca 2+ and other centrins

Fangzhen Shan, Kaiqin Ye, Jiahai Zhang, Shanhui Liao, Xuecheng Zhang, Chao Xu, Xiaoming Tu

Biochem J (2018) 475 (23): 3763–3778.

https://doi.org/10.1042/BCJ20180752

Published: 06 December 2018

View article titled, Solution structure of TbCentrin4 from Trypanosoma brucei and its interactions with Ca 2+ and other centrins

Includes: Supplementary data

Articles

Substrate-inactivated cyclooxygenase-2 is disposed of by exosomes through the ER–Golgi pathway

Esraa Saadi, Sharon Tal, Liza Barki-Harrington

Biochem J (2018) 475 (19): 3141–3151.

https://doi.org/10.1042/BCJ20180530

Published: 12 October 2018

View article titled, Substrate-inactivated cyclooxygenase-2 is disposed of by exosomes through the ER–Golgi pathway

Includes: Supplementary data

Articles

Cilium structure, assembly, and disassembly regulated by the cytoskeleton

In Collection

Editors' pick of review article highlights published in the Biochemical Journal in 2018 & 2019

Mary Mirvis, Tim Stearns, W. James Nelson

Biochem J (2018) 475 (14): 2329–2353.

https://doi.org/10.1042/BCJ20170453

Published: 31 July 2018

View article titled, Cilium structure, assembly, and disassembly regulated by the cytoskeleton

Articles

Plant mitochondrial protein import: the ins and outs

Abi S. Ghifari, Mabel Gill-Hille, Monika W. Murcha

Biochem J (2018) 475 (13): 2191–2208.

https://doi.org/10.1042/BCJ20170521

Published: 16 July 2018

View article titled, Plant mitochondrial protein import: the ins and outs

Articles

Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells

Virginia Actis Dato, Rubén A. Grosso, María C. Sánchez, Claudio M. Fader, Gustavo A. Chiabrando

Biochem J (2018) 475 (9): 1669–1685.

https://doi.org/10.1042/BCJ20170891

Published: 15 May 2018

View article titled, Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells

Includes: Supplementary data

Articles

Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase

Zhenbo Cao, Lorna Mitchell, Oliver Hsia, Miriam Scarpa, Stuart T. Caldwell, Arina D. Alfred, Alexandra Gennaris, Jean-François Collet, Richard C. Hartley, Neil J. Bulleid

Biochem J (2018) 475 (4): 827–838.

https://doi.org/10.1042/BCJ20170929

Published: 28 February 2018

View article titled, Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase

Articles

The hydrophobic region of the Leishmania peroxin 14: requirements for association with a glycosome mimetic membrane

Normand Cyr, Terry K. Smith, Élodie Boisselier, Louis-Philippe Leroux, Anwar Hasil Kottarampatel, Amanda Davidsen, Christian Salesse, Armando Jardim

Biochem J (2018) 475 (2): 511–529.

https://doi.org/10.1042/BCJ20170746

Published: 31 January 2018

View article titled, The hydrophobic region of the Leishmania peroxin 14: requirements for association with a glycosome mimetic membrane

Includes: Supplementary data

Articles

Chloroplast division protein ARC3 acts on FtsZ2 by preventing filament bundling and enhancing GTPase activity

Rahamthulla S. Shaik, Min Woo Sung, Stanislav Vitha, Andreas Holzenburg

Biochem J (2018) 475 (1): 99–115.

https://doi.org/10.1042/BCJ20170697

Published: 02 January 2018

View article titled, Chloroplast division protein ARC3 acts on FtsZ2 by preventing filament bundling and enhancing GTPase activity

Includes: Supplementary data

Articles

GPI-anchored proteins are confined in subdiffraction clusters at the apical surface of polarized epithelial cells

Simona Paladino, Stéphanie Lebreton, Mickaël Lelek, Patrizia Riccio, Sergio De Nicola, Christophe Zimmer, Chiara Zurzolo

Biochem J (2017) 474 (24): 4075–4090.

https://doi.org/10.1042/BCJ20170582

Published: 01 December 2017

View article titled, GPI-anchored proteins are confined in subdiffraction clusters at the apical surface of polarized epithelial cells

Includes: Supplementary data

Articles

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ

Zahra Erami, Bassem D. Khalil, Gilbert Salloum, Yanhua Yao, Jaclyn LoPiccolo, Aliaksei Shymanets, Bernd Nürnberg, Anne R. Bresnick, Jonathan M. Backer

Biochem J (2017) 474 (23): 3903–3914.

https://doi.org/10.1042/BCJ20170279

Published: 16 November 2017

View article titled, Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ

Articles

IgG light chain-independent secretion of heavy chain dimers: consequence for therapeutic antibody production and design

Chloe L. Stoyle, Paul E. Stephens, David P. Humphreys, Sam Heywood, Katharine Cain, Neil J. Bulleid

Biochem J (2017) 474 (18): 3179–3188.

https://doi.org/10.1042/BCJ20170342

Published: 08 September 2017

View article titled, IgG light chain-independent secretion of heavy chain dimers: consequence for therapeutic antibody production and design

Articles

The functions of Reelin in membrane trafficking and cytoskeletal dynamics: implications for neuronal migration, polarization and differentiation

Jessica Santana, María-Paz Marzolo

Biochem J (2017) 474 (18): 3137–3165.

https://doi.org/10.1042/BCJ20160628

Published: 08 September 2017

View article titled, The functions of Reelin in membrane trafficking and cytoskeletal dynamics: implications for neuronal migration, polarization and differentiation

Articles

Ganglioside glycosyltransferases are S-acylated at conserved cysteine residues involved in homodimerisation

Sabrina Chumpen Ramirez, Fernando M. Ruggiero, Jose Luis Daniotti, Javier Valdez Taubas

Biochem J (2017) 474 (16): 2803–2816.

https://doi.org/10.1042/BCJ20170124

Published: 07 August 2017

View article titled, Ganglioside glycosyltransferases are S-acylated at conserved cysteine residues involved in homodimerisation

Includes: Supplementary data

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