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Articles

Structure and function of MDM2 and MDM4 in health and disease

Ivy Yiyi Zhu, Alec Lloyd, William R. Critchley, Queen Saikia, Dhananjay Jade, Aysha Divan, Elton Zeqiraj, Michael A. Harrison, Christopher J. Brown, Sreenivasan Ponnambalam

Biochem J (2025) 482 (04): 241–262.

https://doi.org/10.1042/BCJ20240757

Published: 17 February 2025

View article titled, Structure and function of MDM2 and MDM4 in health and disease

Articles

USP10 deubiquitinates and stabilizes CD44 leading to enhanced breast cancer cell proliferation, stemness and metastasis

Arppita Sethi, Shivkant Mishra, Vishal Upadhyay, Parul Dubey, Shumaila Siddiqui, Anil Kumar Singh, Sangita Chowdhury, Swati Srivastava, Pragya Srivastava, Prasannajit Sahoo, Madan L. B. Bhatt, Anand Mishra, Arun Kumar Trivedi

Biochem J (2024) 481 (24): 1877–1900.

https://doi.org/10.1042/BCJ20240611

Published: 09 December 2024

View article titled, USP10 deubiquitinates and stabilizes CD44 leading to enhanced breast cancer cell proliferation, stemness and metastasis

Includes: Supplementary data

Articles

Macromolecular crowding and bicarbonate enhance the hydrogen peroxide-induced inactivation of glyceraldehyde-3-phosphate dehydrogenase

Rebecca H. J. Bloemen, Rafael Radi, Michael J. Davies, Eduardo Fuentes-Lemus

Biochem J (2024) 481 (23): 1855–1866.

https://doi.org/10.1042/BCJ20240597

Published: 04 December 2024

View article titled, Macromolecular crowding and bicarbonate enhance the hydrogen peroxide-induced inactivation of glyceraldehyde-3-phosphate dehydrogenase

Includes: Supplementary data

Articles

The uncharacterized protein ZNF200 interacts with PRMT3 and aids its stability and nuclear translocation

Somlee Gupta, Mamta Verma, Rajashekar Varma Kadumuri, Namita Chutani, Mohd. Imran K. Khan, Sreenivas Chavali, Arunkumar Dhayalan

Biochem J (2024) 481 (23): 1723–1740.

https://doi.org/10.1042/BCJ20240476

Published: 21 November 2024

View article titled, The uncharacterized protein ZNF200 interacts with PRMT3 and aids its stability and nuclear translocation

Includes: Supplementary data

Articles

Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain

Yizhuo Wang, James E.B. Curson, Divya Ramnath, Kaustav Das Gupta, Robert C. Reid, Denuja Karunakaran, David P. Fairlie, Matthew J. Sweet

Biochem J (2024) 481 (21): 1569–1584.

https://doi.org/10.1042/BCJ20240380

Published: 25 October 2024

View article titled, Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain

Articles

The impact of cell states on heterochromatin dynamics

Abby Trouth, Giovana M. B. Veronezi, Srinivas Ramachandran

Biochem J (2024) 481 (21): 1519–1533.

https://doi.org/10.1042/BCJ20240139

Published: 18 October 2024

View article titled, The impact of cell states on heterochromatin dynamics

Articles

Revamped role for approved drug: integrative computational and biophysical analysis of saquinavir's peptidyl arginine deiminase 4 inhibition for rheumatoid arthritis

Indhumathi Thirugnanasambandham, Srikanth Jupudi, Parikshit Roychowdhury, Veera Venkata Satyanarayana Reddy Karri, Subba Rao V. Madhunapantula, Sachin Kumar Singh, Vetriselvan Subramaniyan, Gowthamarajan Kuppusamy

Biochem J (2024) 481 (20): 1379–1393.

https://doi.org/10.1042/BCJ20240366

Published: 07 October 2024

View article titled, Revamped role for approved drug: integrative computational and biophysical analysis of saquinavir's peptidyl arginine deiminase 4 inhibition for rheumatoid arthritis

Includes: Supplementary data

Articles

The pro-drug C13 activates AMPK by two distinct mechanisms

Jordana B. Freemantle, Dinesh Shah, Dylan M. Lynch, Alessio Ciulli, Harinder S. Hundal, D. Grahame Hardie

Biochem J (2024) 481 (18): 1203–1219.

https://doi.org/10.1042/BCJ20240425

Published: 12 September 2024

View article titled, The pro-drug C13 activates AMPK by two distinct mechanisms

Includes: Supplementary data

Articles

E3 ligases: a ubiquitous link between DNA repair, DNA replication and human disease

Anoop S. Chauhan, Satpal S. Jhujh, Grant S. Stewart

Biochem J (2024) 481 (14): 923–944.

https://doi.org/10.1042/BCJ20240124

Published: 10 July 2024

View article titled, E3 ligases: a ubiquitous link between DNA repair, DNA replication and human disease

Articles

Retraction: Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterin

Biochem J (2024) 481 (14): 957.

https://doi.org/10.1042/BJ20040158_RET

Published: 10 July 2024

View article titled, Retraction: Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterin

Articles

Pepper catalase: a broad analysis of its modulation during fruit ripening and by nitric oxide

Salvador González-Gordo, Javier López-Jaramillo, Marta Rodríguez-Ruiz, Jorge Taboada, José M. Palma, Francisco J. Corpas

Biochem J (2024) 481 (13): 883–901.

https://doi.org/10.1042/BCJ20240247

Published: 03 July 2024

View article titled, Pepper catalase: a broad analysis of its modulation during fruit ripening and by nitric oxide

Includes: Supplementary data

Articles

Charting the importance of filamin A posttranslational modifications

Kyle D. Shead, Veneta Salyahetdinova, George S. Baillie

Biochem J (2024) 481 (13): 865–881.

https://doi.org/10.1042/BCJ20240121

Published: 03 July 2024

View article titled, Charting the importance of filamin A posttranslational modifications

Articles

Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia

Anil Kumar Singh, Vishal Upadhyay, Arppita Sethi, Sangita Chowdhury, Shivkant Mishra, Shailendra Prasad Verma, Madan Lal Brahma Bhatt, Arun Kumar Trivedi

Biochem J (2024) 481 (10): 653–666.

https://doi.org/10.1042/BCJ20240027

Published: 10 May 2024

View article titled, Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia

Includes: Supplementary data

Articles

Validation of GCN5L1/BLOC1S1/BLOS1 antibodies using knockout cells and tissue

Paramesha Bugga, Michael W. Stoner, Janet R. Manning, Bellina A.S. Mushala, Nisha Bhattarai, Maryam Sharifi-Sanjani, Bradley R. Webster, Dharendra Thapa, Iain Scott

Biochem J (2024) 481 (10): 643–651.

https://doi.org/10.1042/BCJ20230302

Published: 10 May 2024

View article titled, Validation of GCN5L1/BLOC1S1/BLOS1 antibodies using knockout cells and tissue

Includes: Supplementary data

Articles

AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand

Simon A. Hawley, Fiona M. Russell, D. Grahame Hardie

Biochem J (2024) 481 (8): 587–599.

https://doi.org/10.1042/BCJ20240082

Published: 22 April 2024

View article titled, AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand

Includes: Supplementary data

Articles

DoUBLing up: ubiquitin and ubiquitin-like proteases in genome stability

Benjamin M. Foster, Zijuan Wang, Christine K. Schmidt

Biochem J (2024) 481 (7): 515–545.

https://doi.org/10.1042/BCJ20230284

Published: 04 April 2024

View article titled, DoUBLing up: ubiquitin and ubiquitin-like proteases in genome stability

Articles

The deubiquitinase function of ataxin-3 and its role in the pathogenesis of Machado-Joseph disease and other diseases

Anastasiya Potapenko, Jennilee M. Davidson, Albert Lee, Angela S. Laird

Biochem J (2024) 481 (6): 461–480.

https://doi.org/10.1042/BCJ20240017

Published: 18 March 2024

View article titled, The deubiquitinase function of ataxin-3 and its role in the pathogenesis of Machado-Joseph disease and other diseases

Articles

Mesenteric artery smooth muscle cells from hypertensive rats have increased microtubule acetylation

Anthony M. Mozzicato, Joakim A. Bastrup, Jose L. Sanchez-Alonso, Jennifer van der Horst, Julia Gorelik, Per Hägglund, Thomas A. Jepps

Biochem J (2024) 481 (5): 387–403.

https://doi.org/10.1042/BCJ20230420

Published: 29 February 2024

View article titled, Mesenteric artery smooth muscle cells from hypertensive rats have increased microtubule acetylation

Includes: Supplementary data

Articles

Dynamic interactions between SPX proteins, the ubiquitination machinery, and signalling molecules for stress adaptation at a whole-plant level

Emma Collins, Huixia Shou, Chuanzao Mao, James Whelan, Ricarda Jost

Biochem J (2024) 481 (5): 363–385.

https://doi.org/10.1042/BCJ20230163

Published: 29 February 2024

View article titled, Dynamic interactions between SPX proteins, the ubiquitination machinery, and signalling molecules for stress adaptation at a whole-plant level

Articles

The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress

Katy R. McCarron, Hannah Elcocks, Heather Mortiboys, Sylvie Urbé, Michael J. Clague

Biochem J (2024) 481 (4): 265–278.

https://doi.org/10.1042/BCJ20230492

Published: 15 February 2024

View article titled, The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress

Includes: Supplementary data

Articles

Beyond the tail: the consequence of context in histone post-translational modification and chromatin research

In Collection

Epigenetics

Ellen N. Weinzapfel, Karlie N. Fedder-Semmes, Zu-Wen Sun, Michael-Christopher Keogh

Biochem J (2024) 481 (4): 219–244.

https://doi.org/10.1042/BCJ20230342

Published: 14 February 2024

View article titled, Beyond the tail: the consequence of context in histone post-translational modification and chromatin research

Articles

The role of phosphorylation in calmodulin-mediated gating of human AQP0

Stefan Kreida, Jennifer Virginia Roche, Julie Winkel Missel, Tamim Al-Jubair, Carl Johan Hagströmer, Veronika Wittenbecher, Sara Linse, Pontus Gourdon, Susanna Törnroth-Horsefield

Biochem J (2024) 481 (1): 17–32.

https://doi.org/10.1042/BCJ20230158

Published: 04 January 2024

View article titled, The role of phosphorylation in calmodulin-mediated gating of human AQP0

Includes: Supplementary data

Articles

Non-cross-linking advanced glycation end products affect prohormone processing

Sebastian Brings, Walter Mier, Barbro Beijer, Elisabeth Kliemank, Stephan Herzig, Julia Szendroedi, Peter P. Nawroth, Thomas Fleming

Biochem J (2024) 481 (1): 33–44.

https://doi.org/10.1042/BCJ20230321

Published: 04 January 2024

View article titled, Non-cross-linking advanced glycation end products affect prohormone processing

Includes: Supplementary data

Articles

Into the fold: advances in understanding aPKC membrane dynamics

In Collection

Cell signaling in the 21st century

Mathias Cobbaut, Peter J. Parker, Neil Q. McDonald

Biochem J (2023) 480 (24): 2037–2044.

https://doi.org/10.1042/BCJ20230390

Published: 15 December 2023

View article titled, Into the fold: advances in understanding aPKC membrane dynamics

Articles

Lysine methylation signaling in skeletal muscle biology: from myogenesis to clinical insights

In Collection

Epigenetics

Eric Cordeiro-Spinetti, Scott B. Rothbart

Biochem J (2023) 480 (23): 1969–1986.

https://doi.org/10.1042/BCJ20230223

Published: 06 December 2023

View article titled, Lysine methylation signaling in skeletal muscle biology: from myogenesis to clinical insights

Articles

Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers

Fiona A. Ross, Simon A. Hawley, Fiona M. Russell, Nicola Goodman, D. Grahame Hardie

Biochem J (2023) 480 (23): 1951–1968.

https://doi.org/10.1042/BCJ20230380

Published: 01 December 2023

View article titled, Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers

Articles

Loss of the methylarginine reader function of SND1 confers resistance to hepatocellular carcinoma

In Collection

Epigenetics

Tanner Wright, Yalong Wang, Sabrina A. Stratton, Manu Sebastian, Bin Liu, David G. Johnson, Mark T. Bedford

Biochem J (2023) 480 (22): 1805–1816.

https://doi.org/10.1042/BCJ20230384

Published: 17 November 2023

View article titled, Loss of the methylarginine reader function of SND1 confers resistance to hepatocellular carcinoma

Articles

UBE2A/B is the trans -acting factor mediating mechanotransduction and contact inhibition

Mingwei Feng, Jiale Wang, Kangjing Li, Fumihiko Nakamura

Biochem J (2023) 480 (20): 1659–1674.

https://doi.org/10.1042/BCJ20230208

Published: 19 October 2023

View article titled, UBE2A/B is the trans -acting factor mediating mechanotransduction and contact inhibition

Includes: Supplementary data

Articles

ISGylation-independent protection of cell growth by USP18 following interferon stimulation

Anne Clancy, Emma V. Rusilowicz-Jones, Iona Wallace, Kirby N. Swatek, Sylvie Urbé, Michael J. Clague

Biochem J (2023) 480 (19): 1571–1581.

https://doi.org/10.1042/BCJ20230301

Published: 09 October 2023

View article titled, ISGylation-independent protection of cell growth by USP18 following interferon stimulation

Articles

The choreography of protein kinase PDK1 and its diverse substrate dance partners

In Collection

Cell signaling in the 21st century

Alejandro E. Leroux, Ricardo M. Biondi

Biochem J (2023) 480 (19): 1503–1532.

https://doi.org/10.1042/BCJ20220396

Published: 04 October 2023

View article titled, The choreography of protein kinase PDK1 and its diverse substrate dance partners

Articles

Lhs1 dependent ERAD is determined by transmembrane domain context

Maria Sukhoplyasova, Abigail M. Keith, Emma M. Perrault, Hannah E. Vorndran, Alexa S. Jordahl, Megan E. Yates, Ashutosh Pastor, Zachary Li, Michael L. Freaney, Riddhi A. Deshpande, David B. Adams, Christopher J. Guerriero, Shujie Shi, Thomas R. Kleyman, Ossama B. Kashlan, Jeffrey L. Brodsky, Teresa M. Buck

Biochem J (2023) 480 (18): 1459–1473.

https://doi.org/10.1042/BCJ20230075

Published: 21 September 2023

View article titled, Lhs1 dependent ERAD is determined by transmembrane domain context

Includes: Supplementary data

Articles

Development of an OTUD1 ubiquitin variant inhibitor

Qi Liu, Evan Mallette, Hui Zheng, Wei Zhang

Biochem J (2023) 480 (16): 1317–1330.

https://doi.org/10.1042/BCJ20230119

Published: 25 August 2023

View article titled, Development of an OTUD1 ubiquitin variant inhibitor

Includes: Supplementary data

Articles

A global view of the human post-translational modification landscape

In Collection

Cell signaling in the 21st century

Naoya Kitamura, James J. Galligan

Biochem J (2023) 480 (16): 1241–1265.

https://doi.org/10.1042/BCJ20220251

Published: 23 August 2023

View article titled, A global view of the human post-translational modification landscape

Articles

Emerging functions of pseudoenzymes

In Collection

Cell signaling in the 21st century

Timea Goldberg, Anju Sreelatha

Biochem J (2023) 480 (10): 715–728.

https://doi.org/10.1042/BCJ20220373

Published: 19 May 2023

View article titled, Emerging functions of pseudoenzymes

Articles

Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia

W. Bruce Sneddon, Peter A. Friedman, Tatyana Mamonova

Biochem J (2023) 480 (9): 685–699.

https://doi.org/10.1042/BCJ20230020

Published: 17 May 2023

View article titled, Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia

Articles

Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module

Ishita Bardhan, Soumen Barman, Anirban Roy, Babu Sudhamalla

Biochem J (2023) 480 (9): 629–647.

https://doi.org/10.1042/BCJ20230011

Published: 10 May 2023

View article titled, Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module

Includes: Supplementary data

Articles

ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1

In Collection

Cell signaling in the 21st century

Kathryn Balmanno, Andrew M. Kidger, Dominic P. Byrne, Matthew J. Sale, Nejma Nassman, Patrick A. Eyers, Simon J. Cook

Biochem J (2023) 480 (9): 587–605.

https://doi.org/10.1042/BCJ20220598

Published: 04 May 2023

View article titled, ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1

Includes: Supplementary data

Articles

Overexpression of ARM repeat/U-box containing E3 ligase, PUB2 positively regulates growth and oxidative stress response in Arabidopsis

In Collection

Plants and climate change: the role of plants in achieving net zero

Lokesh K. Saini, Manisha Sharma, Barkha Ravi, Soma Ghosh, Sonam Pahuja, Nidhi Singh, Girdhar K. Pandey

Biochem J (2023) 480 (9): 555–571.

https://doi.org/10.1042/BCJ20230026

Published: 28 April 2023

View article titled, Overexpression of ARM repeat/U-box containing E3 ligase, PUB2 positively regulates growth and oxidative stress response in Arabidopsis

Articles

Protein kinase C showcases allosteric control: activation of LRRK1

Hannah Tovell, Alexandra C. Newton

Biochem J (2023) 480 (3): 219–223.

https://doi.org/10.1042/BCJ20220507

Published: 10 February 2023

View article titled, Protein kinase C showcases allosteric control: activation of LRRK1

Articles

Characterizing crosstalk in epigenetic signaling to understand disease physiology

In Collection

Cell signaling in the 21st century

Joanna K. Lempiäinen, Benjamin A. Garcia

Biochem J (2023) 480 (1): 57–85.

https://doi.org/10.1042/BCJ20220550

Published: 11 January 2023

View article titled, Characterizing crosstalk in epigenetic signaling to understand disease physiology

Articles

Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12

Elisha H. McCrory, Vyacheslav Akimov, Philip Cohen, Blagoy Blagoev

Biochem J (2022) 479 (23): 2419–2431.

https://doi.org/10.1042/BCJ20220510

Published: 07 December 2022

View article titled, Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12

Includes: Supplementary data

Articles

Poly-ADP ribosylation of p21 by tankyrases promotes p21 degradation and regulates cell cycle progression

Misun Jung, Wonyoung Kim, Jin Won Cho, Won Ho Yang, In Kwon Chung

Biochem J (2022) 479 (22): 2379–2394.

https://doi.org/10.1042/BCJ20220391

Published: 30 November 2022

View article titled, Poly-ADP ribosylation of p21 by tankyrases promotes p21 degradation and regulates cell cycle progression

Includes: Supplementary data

Articles

The C-terminal region of phytoene synthase is a key element to control carotenoid biosynthesis in the haloarchaeon Haloferax volcanii

Micaela Cerletti, Agustín Rabino, Roberto A. Paggi, Celeste Ferrari, Ansgar Poetsch, Harri Savilahti, Saija Kiljunen, Rosana E. De Castro

Biochem J (2022) 479 (22): 2365–2377.

https://doi.org/10.1042/BCJ20220403

Published: 23 November 2022

View article titled, The C-terminal region of phytoene synthase is a key element to control carotenoid biosynthesis in the haloarchaeon Haloferax volcanii

Includes: Supplementary data

Articles

AMP-activated protein kinase — a journey from 1 to 100 downstream targets

In Collection

Awards

D. Grahame Hardie

Biochem J (2022) 479 (22): 2327–2343.

https://doi.org/10.1042/BCJ20220255

Published: 16 November 2022

View article titled, AMP-activated protein kinase — a journey from 1 to 100 downstream targets

Articles

Methylglyoxal induces multiple serine phosphorylation in insulin receptor substrate 1 via the TAK1–p38–mTORC1 signaling axis in adipocytes

Su-Ping Ng, Wataru Nomura, Haruya Takahashi, Kazuo Inoue, Teruo Kawada, Tsuyoshi Goto, Yoshiharu Inoue

Biochem J (2022) 479 (21): 2279–2296.

https://doi.org/10.1042/BCJ20220271

Published: 04 November 2022

View article titled, Methylglyoxal induces multiple serine phosphorylation in insulin receptor substrate 1 via the TAK1–p38–mTORC1 signaling axis in adipocytes

Includes: Supplementary data

Articles

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells

Jill E. Hunter, Amy E. Campbell, Scott Kerridge, Callum Fraser, Nicola L. Hannaway, Saimir Luli, Iglika Ivanova, Philip J. Brownridge, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S. R. Hasoon, Claire E. Eyers, Neil D. Perkins

Biochem J (2022) 479 (19): 2131–2151.

https://doi.org/10.1042/BCJ20220103

Published: 14 October 2022

View article titled, Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells

Includes: Supplementary data

Articles

PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the COR B GTPase domain

Asad U. Malik, Athanasios Karapetsas, Raja S. Nirujogi, Deep Chatterjee, Toan K. Phung, Melanie Wightman, Robert Gourlay, Nick Morrice, Sebastian Mathea, Stefan Knapp, Dario R. Alessi

Biochem J (2022) 479 (18): 1941–1965.

https://doi.org/10.1042/BCJ20220308

Published: 23 September 2022

View article titled, PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the COR B GTPase domain

Articles

Divergent kinase WNG1 is regulated by phosphorylation of an atypical activation sub-domain

Pravin S. Dewangan, Tsebaot G. Beraki, E. Ariana Paiz, Delia Appiah Mensah, Zhe Chen, Michael L. Reese

Biochem J (2022) 479 (17): 1877–1889.

https://doi.org/10.1042/BCJ20220076

Published: 16 September 2022

View article titled, Divergent kinase WNG1 is regulated by phosphorylation of an atypical activation sub-domain

Includes: Supplementary data

Articles

Common and unique features of glycosylation and glycosyltransferases in African trypanosomes

Samuel M. Duncan, Michael A.J. Ferguson

Biochem J (2022) 479 (17): 1743–1758.

https://doi.org/10.1042/BCJ20210778

Published: 06 September 2022

View article titled, Common and unique features of glycosylation and glycosyltransferases in African trypanosomes

Articles

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding

Alexia F. Kalogeropulou, Elena Purlyte, Francesca Tonelli, Sven M. Lange, Melanie Wightman, Alan R. Prescott, Shalini Padmanabhan, Esther Sammler, Dario R. Alessi

Biochem J (2022) 479 (17): 1759–1783.

https://doi.org/10.1042/BCJ20220161

Published: 06 September 2022

View article titled, Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding

Includes: Supplementary data

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