Page 1 | Search Results | Biochemical Journal

1-50 of 78

Sort by

Sort Order Select

Articles

Biochemical basis and therapeutic potential of mitochondrial uncoupling in cardiometabolic syndrome

Bernardo Gindri dos Santos, Niki F. Brisnovali, Leigh Goedeke

Biochem J (2024) 481 (23): 1831–1854.

https://doi.org/10.1042/BCJ20240005

Published: 04 December 2024

View articletitled, Biochemical basis and therapeutic potential of mitochondrial uncoupling in cardiometabolic syndrome

Articles

Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression

Takumi Sato, Ryota Shizu, Ryonosuke Baba, Akira Ooka, Takuomi Hosaka, Yuichiro Kanno, Kouichi Yoshinari

Biochem J (2024) 481 (18): 1173–1186.

https://doi.org/10.1042/BCJ20240172

Published: 06 September 2024

View articletitled, Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression

Includes: Supplementary data

Articles

Integrating bacterial molecular genetics with chemical biology for renewed antibacterial drug discovery

Susannah L. Parkhill, Eachan O. Johnson

Biochem J (2024) 481 (13): 839–864.

https://doi.org/10.1042/BCJ20220062

Published: 03 July 2024

View articletitled, Integrating bacterial molecular genetics with chemical biology for renewed antibacterial drug discovery

Articles

Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway

In Collection

Cell signaling in the 21st century

Laura Weatherdon, Kate Stuart, Megan Cassidy, Alberto Moreno de la Gándara, Hanneke Okkenhaug, Markus Muellener, Grahame Mckenzie, Simon J. Cook, Rebecca Gilley

Biochem J (2024) 481 (6): 405–422.

https://doi.org/10.1042/BCJ20240015

Published: 07 March 2024

View articletitled, Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway

Includes: Supplementary data

Articles

Leukotriene B4 receptor 1 does not mediate disease progression in a mouse model of liver fibrosis

Erin S. Coyne, Yilin Nie, Desiree Abdurrachim, Charlene Zhi Lin Ong, Yongqi Zhou, Asad Abu Bakar Ali, Stacey Meyers, Jeff Grein, Wendy Blumenschein, Brendan Gongol, Yang Liu, Cedric Hugelshofer, Ester Carballo-Jane, Saswata Talukdar

Biochem J (2024) 481 (3): 177–190.

https://doi.org/10.1042/BCJ20230422

Published: 05 February 2024

View articletitled, Leukotriene B4 receptor 1 does not mediate disease progression in a mouse model of liver fibrosis

Includes: Supplementary data

Articles

Understanding interleukin 11 as a disease gene and therapeutic target

Stuart A. Cook

Biochem J (2023) 480 (23): 1987–2008.

https://doi.org/10.1042/BCJ20220160

Published: 06 December 2023

View articletitled, Understanding interleukin 11 as a disease gene and therapeutic target

Articles

Polypharmacological repurposing approach identifies approved drugs as potential inhibitors of Mycobacterium tuberculosis

Jasdeep Singh, Neha Quadir, Shubham Vashishtha, Ankan Chakraborty, Anwar Alam, Bishwajit Kundu, Uzair Ahmad, Durai Sundar, Nasreen Z. Ehtesham, Seyed E. Hasnain

Biochem J (2023) 480 (14): 1079–1096.

https://doi.org/10.1042/BCJ20230143

Published: 17 July 2023

View articletitled, Polypharmacological repurposing approach identifies approved drugs as potential inhibitors of Mycobacterium tuberculosis

Includes: Supplementary data

Articles

ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1

In Collection

Cell signaling in the 21st century

Kathryn Balmanno, Andrew M. Kidger, Dominic P. Byrne, Matthew J. Sale, Nejma Nassman, Patrick A. Eyers, Simon J. Cook

Biochem J (2023) 480 (9): 587–605.

https://doi.org/10.1042/BCJ20220598

Published: 04 May 2023

View articletitled, ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1

Includes: Supplementary data

Articles

Impact of fluoroquinolones and aminoglycosides on P. aeruginosa virulence factor production and cytotoxicity

Daniel M. Foulkes, Keri McLean, Marta Sloniecka, Sophie Rustidge, Dominic P. Byrne, Atikah S. Haneef, Craig Winstanley, Neil Berry, David G. Fernig, Stephen B. Kaye

Biochem J (2022) 479 (24): 2511–2527.

https://doi.org/10.1042/BCJ20220527

Published: 22 December 2022

View articletitled, Impact of fluoroquinolones and aminoglycosides on P. aeruginosa virulence factor production and cytotoxicity

Articles

Combinatorial approaches for mitigating resistance to KRAS-targeted therapies

Hannah R. Warren, Sarah J. Ross, Paul D. Smith, Judy M. Coulson, Ian A. Prior

Biochem J (2022) 479 (18): 1985–1997.

https://doi.org/10.1042/BCJ20220440

Published: 23 September 2022

View articletitled, Combinatorial approaches for mitigating resistance to KRAS-targeted therapies

Includes: Supplementary data

Articles

Vitamin K3 inhibits FtsZ assembly, disrupts the Z-ring in Streptococcus pneumoniae and displays anti-pneumococcal activity

Athira Pushpakaran, Rachana Rao Battaje, Dulal Panda

Biochem J (2022) 479 (14): 1543–1558.

https://doi.org/10.1042/BCJ20220077

Published: 21 July 2022

View articletitled, Vitamin K3 inhibits FtsZ assembly, disrupts the Z-ring in Streptococcus pneumoniae and displays anti-pneumococcal activity

Includes: Supplementary data

Articles

Targeting the alternative oxidase (AOX) for human health and food security, a pharmaceutical and agrochemical target or a rescue mechanism?

Marten Szibor, Christina Schenkl, Mario R. O. Barsottini, Luke Young, Anthony L. Moore

Biochem J (2022) 479 (12): 1337–1359.

https://doi.org/10.1042/BCJ20180192

Published: 24 June 2022

View articletitled, Targeting the alternative oxidase (AOX) for human health and food security, a pharmaceutical and agrochemical target or a rescue mechanism?

Articles

Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo

Biochem J (2022) 479 (9): 1007–1030.

https://doi.org/10.1042/BCJ20220054

Published: 13 May 2022

View articletitled, Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo

Includes: Supplementary data

Articles

Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants

Tristram A. J. Ryan, Roger J. S. Preston, Luke A. J. O'Neill

Biochem J (2022) 479 (6): 731–750.

https://doi.org/10.1042/BCJ20210522

Published: 28 March 2022

View articletitled, Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants

Articles

Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches

Eliona Tsefou, Alison S. Walker, Emily H. Clark, Amy R. Hicks, Christin Luft, Kunitoshi Takeda, Toru Watanabe, Bianca Ramazio, James M. Staddon, Thomas Briston, Robin Ketteler

Biochem J (2021) 478 (23): 4099–4118.

https://doi.org/10.1042/BCJ20210508

Published: 06 December 2021

View articletitled, Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches

Includes: Supplementary data

Articles

Crystallographic approach to fragment-based hit discovery against Schistosoma mansoni purine nucleoside phosphorylase

Muhammad Faheem, Napoleão Fonseca Valadares, José Brandão-Neto, Dom Bellini, Patrick Collins, Nicholas M. Pearce, Louise Bird, Juliana Roberta Torini, Raymond Owens, Humberto DMuniz Pereira, Frank Von Delft, João Alexandre Ribeiro Gonçalves Barbosa

Biochem J (2021) 478 (19): 3655–3670.

https://doi.org/10.1042/BCJ20210041

Published: 14 October 2021

View articletitled, Crystallographic approach to fragment-based hit discovery against Schistosoma mansoni purine nucleoside phosphorylase

Articles

Structural and molecular bases to IRE1 activity modulation

Timothy Langlais, Diana Pelizzari-Raymundo, Sayyed Jalil Mahdizadeh, Nicolas Gouault, Francois Carreaux, Eric Chevet, Leif A. Eriksson, Xavier Guillory

Biochem J (2021) 478 (15): 2953–2975.

https://doi.org/10.1042/BCJ20200919

Published: 10 August 2021

View articletitled, Structural and molecular bases to IRE1 activity modulation

Articles

Manipulating the exposome to enable better ageing

Paul G. Shiels, Johanna Painer, Barbara Natterson-Horowitz, Richard J. Johnson, Jaime J. Miranda, Peter Stenvinkel

Biochem J (2021) 478 (14): 2889–2898.

https://doi.org/10.1042/BCJ20200958

Published: 28 July 2021

View articletitled, Manipulating the exposome to enable better ageing

Articles

Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells

Kai-Wen Cheng, Feng Wang, George A. Lopez, Srikanth Singamsetty, Jill Wood, Patricia I. Dickson, Tsui-Fen Chou

Biochem J (2021) 478 (12): 2309–2319.

https://doi.org/10.1042/BCJ20210015

Published: 23 June 2021

View articletitled, Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells

Includes: Supplementary data

Articles

Transforming growth factor-β2-mediated mesenchymal transition in lens epithelial cells is repressed in the absence of RAGE

Mi-Hyun Nam, Mina B. Pantcheva, Johanna Rankenberg, Ram H. Nagaraj

Biochem J (2021) 478 (12): 2285–2296.

https://doi.org/10.1042/BCJ20210069

Published: 18 June 2021

View articletitled, Transforming growth factor-β2-mediated mesenchymal transition in lens epithelial cells is repressed in the absence of RAGE

Includes: Supplementary data

Articles

Integrin αVβ1 regulates procollagen I production through a non-canonical transforming growth factor β signaling pathway in human hepatic stellate cells

Zuoning Han, Yanling Ma, Gary Cao, Zhengping Ma, Ruihua Chen, Mary Ellen Cvijic, Dong Cheng

Biochem J (2021) 478 (9): 1689–1703.

https://doi.org/10.1042/BCJ20200749

Published: 10 May 2021

View articletitled, Integrin αVβ1 regulates procollagen I production through a non-canonical transforming growth factor β signaling pathway in human hepatic stellate cells

Includes: Supplementary data

Articles

α-Methyl-l-tryptophan as a weight-loss agent in multiple models of obesity in mice

Sathish Sivaprakasam, Sabarish Ramachandran, Mohd Omar Faruk Sikder, Yangzom D. Bhutia, Mitchell W. Wachtel, Vadivel Ganapathy

Biochem J (2021) 478 (7): 1347–1358.

https://doi.org/10.1042/BCJ20210100

Published: 06 April 2021

View articletitled, α-Methyl-l-tryptophan as a weight-loss agent in multiple models of obesity in mice

Articles

Organismal roles for the PI3Kα and β isoforms: their specificity, redundancy or cooperation is context-dependent

Silvia Arcucci, Fernanda Ramos-Delgado, Coralie Cayron, Nicole Therville, Marie-Pierre Gratacap, Céline Basset, Benoit Thibault, Julie Guillermet-Guibert

Biochem J (2021) 478 (6): 1199–1225.

https://doi.org/10.1042/BCJ20210004

Published: 19 March 2021

View articletitled, Organismal roles for the PI3Kα and β isoforms: their specificity, redundancy or cooperation is context-dependent

Includes: Supplementary data

Articles

A pipeline to evaluate inhibitors of the Pseudomonas aeruginosa exotoxin U

Daniel M. Foulkes, Keri McLean, Yalin Zheng, Joscelyn Sarsby, Atikah S. Haneef, David G. Fernig, Craig Winstanley, Neil Berry, Stephen B. Kaye

Biochem J (2021) 478 (3): 647–668.

https://doi.org/10.1042/BCJ20200780

Published: 12 February 2021

View articletitled, A pipeline to evaluate inhibitors of the Pseudomonas aeruginosa exotoxin U

Includes: Supplementary data

Articles

Weakening of interaction networks with aging in tip-link protein induces hearing loss

Surbhi Garg, Amin Sagar, Gayathri S. Singaraju, Rahul Dani, Naimat K. Bari, Athi N. Naganathan, Sabyasachi Rakshit

Biochem J (2021) 478 (1): 121–134.

https://doi.org/10.1042/BCJ20200799

Published: 13 January 2021

View articletitled, Weakening of interaction networks with aging in tip-link protein induces hearing loss

Includes: Multimedia, Supplementary data

Articles

Multistep optimization of a cell-penetrating peptide towards its antimicrobial activity

Marco Drexelius, Andre Reinhardt, Joshua Grabeck, Tom Cronenberg, Frank Nitsche, Pitter F. Huesgen, Berenike Maier, Ines Neundorf

Biochem J (2021) 478 (1): 63–78.

https://doi.org/10.1042/BCJ20200698

Published: 08 January 2021

View articletitled, Multistep optimization of a cell-penetrating peptide towards its antimicrobial activity

Includes: Supplementary data

Articles

Translesion synthesis of the major nitrogen mustard-induced DNA lesion by human DNA polymerase η

Hunmin Jung, Naveen Kumar Rayala, Seongmin Lee

Biochem J (2020) 477 (23): 4543–4558.

https://doi.org/10.1042/BCJ20200767

Published: 03 December 2020

View articletitled, Translesion synthesis of the major nitrogen mustard-induced DNA lesion by human DNA polymerase η

Articles

Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics

Agnès Ribes, Antoine Oprescu, Julien Viaud, Karim Hnia, Gaëtan Chicanne, Jean-Marie Xuereb, Sonia Severin, Marie-Pierre Gratacap, Bernard Payrastre

Biochem J (2020) 477 (22): 4327–4342.

https://doi.org/10.1042/BCJ20190402

Published: 26 November 2020

View articletitled, Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics

Articles

Structure-based drug repurposing to inhibit the DNA gyrase of Mycobacterium tuberculosis

Balasubramani GL, Rinky Rajput, Manish Gupta, Pradeep Dahiya, Jitendra K. Thakur, Rakesh Bhatnagar, Abhinav Grover

Biochem J (2020) 477 (21): 4167–4190.

https://doi.org/10.1042/BCJ20200462

Published: 09 November 2020

View articletitled, Structure-based drug repurposing to inhibit the DNA gyrase of Mycobacterium tuberculosis

Includes: Supplementary data

Articles

Exploiting S- nitrosylation for cancer therapy: facts and perspectives

Salvatore Rizza, Giuseppe Filomeni

Biochem J (2020) 477 (19): 3649–3672.

https://doi.org/10.1042/BCJ20200064

Published: 05 October 2020

View articletitled, Exploiting S- nitrosylation for cancer therapy: facts and perspectives

Articles

New insights on the interaction mechanism of rhTNFα with its antagonists Adalimumab and Etanercept

María Angélica Contreras, Luis Macaya, Pedro Neira, Frank Camacho, Alaín González, Jannel Acosta, Raquel Montesino, Jorge Roberto Toledo, Oliberto Sánchez

Biochem J (2020) 477 (17): 3299–3311.

https://doi.org/10.1042/BCJ20200568

Published: 10 September 2020

View articletitled, New insights on the interaction mechanism of rhTNFα with its antagonists Adalimumab and Etanercept

Articles

RAS Function in cancer cells: translating membrane biology and biochemistry into new therapeutics

Walaa E. Kattan, John F. Hancock

Biochem J (2020) 477 (15): 2893–2919.

https://doi.org/10.1042/BCJ20190839

Published: 14 August 2020

View articletitled, RAS Function in cancer cells: translating membrane biology and biochemistry into new therapeutics

Articles

Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases

Nikola Maraković, Anamarija Knežević, Igor Rončević, Xavier Brazzolotto, Zrinka Kovarik, Goran Šinko

Biochem J (2020) 477 (15): 2771–2790.

https://doi.org/10.1042/BCJ20200192

Published: 07 August 2020

View articletitled, Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases

Includes: Supplementary data

Articles

Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics

Dominic P. Byrne, Christopher J. Clarke, Philip J. Brownridge, Anton Kalyuzhnyy, Simon Perkins, Amy Campbell, David Mason, Andrew R. Jones, Patrick A. Eyers, Claire E. Eyers

Biochem J (2020) 477 (13): 2451–2475.

https://doi.org/10.1042/BCJ20200309

Published: 02 July 2020

View articletitled, Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics

Includes: Supplementary data

Articles

Synergism between SLC6A14 blockade and gemcitabine in pancreactic cancer: a 1 H-NMR-based metabolomic study in pancreatic cancer cells

Aimin Cai, Hailun Zheng, Zhiwei Chen, Xinlu Lin, Chen Li, Qing yao, Yangzom D. Bhutia, Vadivel Ganapathy, Ruijie Chen, Longfa Kou

Biochem J (2020) 477 (10): 1923–1937.

https://doi.org/10.1042/BCJ20200275

Published: 29 May 2020

View articletitled, Synergism between SLC6A14 blockade and gemcitabine in pancreactic cancer: a 1 H-NMR-based metabolomic study in pancreatic cancer cells

Includes: Supplementary data

Articles

SLC6A14, a Na + /Cl − -coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling

Mohd O. F. Sikder, Sathish Sivaprakasam, Timothy P. Brown, Muthusamy Thangaraju, Yangzom D. Bhutia, Vadivel Ganapathy

Biochem J (2020) 477 (8): 1409–1425.

https://doi.org/10.1042/BCJ20200099

Published: 23 April 2020

View articletitled, SLC6A14, a Na + /Cl − -coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling

Includes: Supplementary data

Articles

Cell-penetrating peptides: two faces of the same coin

Giovanna Maria Pierantoni, Simona Paladino

Biochem J (2020) 477 (8): 1363–1366.

https://doi.org/10.1042/BCJ20200006

Published: 23 April 2020

View articletitled, Cell-penetrating peptides: two faces of the same coin

Articles

The antifungal peptide CGA-N12 inhibits cell wall synthesis of Candida tropicalis by interacting with KRE9

Ruifang Li, Zhengwei Liu, Weibing Dong, Lan Zhang, Beibei Zhang, Dandan Li, Caiwei Fu

Biochem J (2020) 477 (3): 747–762.

https://doi.org/10.1042/BCJ20190678

Published: 14 February 2020

View articletitled, The antifungal peptide CGA-N12 inhibits cell wall synthesis of Candida tropicalis by interacting with KRE9

Includes: Supplementary data

Articles

Lysosomal protein thermal stability does not correlate with cellular half-life: global observations and a case study of tripeptidyl-peptidase 1

Aaron M. Collier, Yuliya Nemtsova, Narendra Kuber, Whitney Banach-Petrosky, Anurag Modak, David E. Sleat, Vikas Nanda, Peter Lobel

Biochem J (2020) 477 (3): 727–745.

https://doi.org/10.1042/BCJ20190874

Published: 14 February 2020

View articletitled, Lysosomal protein thermal stability does not correlate with cellular half-life: global observations and a case study of tripeptidyl-peptidase 1

Includes: Supplementary data

Articles

Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease

Susanne Seemann, Mathias Ernst, Chiara Cimmaruta, Stephan Struckmann, Claudia Cozma, Dirk Koczan, Anne-Marie Knospe, Linda Rebecca Haake, Valentina Citro, Anja U. Bräuer, Giuseppina Andreotti, Maria Vittoria Cubellis, Georg Fuellen, Andreas Hermann, Anne-Katrin Giese, Arndt Rolfs, Jan Lukas

Biochem J (2020) 477 (2): 359–380.

https://doi.org/10.1042/BCJ20190513

Published: 30 January 2020

View articletitled, Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease

Includes: Supplementary data

Articles

EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

N.G. Eissa, E.J. Sayers, D. Birch, S.G. Patel, Y.-H. Tsai, H. Mørck Nielsen, A.T. Jones

Biochem J (2020) 477 (1): 45–60.

https://doi.org/10.1042/BCJ20190452

Published: 08 January 2020

View articletitled, EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

Includes: Multimedia, Supplementary data

Articles

Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Mirco Dindo, Silvia Grottelli, Giannamaria Annunziato, Giorgio Giardina, Marco Pieroni, Gioena Pampalone, Andrea Faccini, Francesca Cutruzzolà, Paola Laurino, Gabriele Costantino, Barbara Cellini

Biochem J (2019) 476 (24): 3751–3768.

https://doi.org/10.1042/BCJ20190507

Published: 20 December 2019

View articletitled, Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Includes: Supplementary data

Articles

Structural insights into Escherichia coli phosphopantothenoylcysteine synthetase by native ion mobility–mass spectrometry

Daniel Shiu-Hin Chan, Jeannine Hess, Elen Shaw, Christina Spry, Robert Starley, Claudio Dagostin, Marcio V. B. Dias, Ramesh Kale, Vitor Mendes, Tom L. Blundell, Anthony G. Coyne, Chris Abell

Biochem J (2019) 476 (21): 3125–3139.

https://doi.org/10.1042/BCJ20190318

Published: 05 November 2019

View articletitled, Structural insights into Escherichia coli phosphopantothenoylcysteine synthetase by native ion mobility–mass spectrometry

Includes: Supplementary data

Articles

Molecular, chemical, and structural characterization of prostaglandin A 2 as a novel agonist for Nur77

Sowmya P. Lakshmi, Aravind T. Reddy, Asoka Banno, Raju C. Reddy

Biochem J (2019) 476 (19): 2757–2767.

https://doi.org/10.1042/BCJ20190253

Published: 11 October 2019

View articletitled, Molecular, chemical, and structural characterization of prostaglandin A 2 as a novel agonist for Nur77

Includes: Multimedia, Supplementary data

Articles

A novel small molecule A 2A adenosine receptor agonist, indirubin-3′-monoxime, alleviates lipid-induced inflammation and insulin resistance in 3T3-L1 adipocytes

Saynaz A. Choudhary, Nikita Bora, Dipanjan Banerjee, Leena Arora, Anindhya Sundar Das, Rakesh Yadav, Karl-Norbert Klotz, Durba Pal, Anupam Nath Jha, Suman Dasgupta

Biochem J (2019) 476 (16): 2371–2391.

https://doi.org/10.1042/BCJ20190251

Published: 30 August 2019

View articletitled, A novel small molecule A 2A adenosine receptor agonist, indirubin-3′-monoxime, alleviates lipid-induced inflammation and insulin resistance in 3T3-L1 adipocytes

Includes: Supplementary data

Articles

Toxins for decoding interface selectivity in nicotinic acetylcholine receptors

R. Manjunatha Kini

Biochem J (2019) 476 (10): 1515–1520.

https://doi.org/10.1042/BCJ20190255

Published: 28 May 2019

View articletitled, Toxins for decoding interface selectivity in nicotinic acetylcholine receptors

Articles

A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells

In Collection

Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019

Mam Y. Mboge, Zhijuan Chen, Daniel Khokhar, Alyssa Wolff, Lingbao Ai, Coy D. Heldermon, Murat Bozdag, Fabrizio Carta, Claudiu T. Supuran, Kevin D. Brown, Robert McKenna, Christopher J. Frost, Susan C. Frost

Biochem J (2019) 476 (10): 1497–1513.

https://doi.org/10.1042/BCJ20190177

Published: 28 May 2019

View articletitled, A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells

Includes: Supplementary data

Articles

Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity

Alvin Gomez, Christian Bindesbøll, Somisetty V. Satheesh, Giulia Grimaldi, David Hutin, Laura MacPherson, Shaimaa Ahmed, Laura Tamblyn, Tiffany Cho, Hilde Irene Nebb, Anders Moen, Jan Haug Anonsen, Denis M. Grant, Jason Matthews

Biochem J (2018) 475 (23): 3827–3846.

https://doi.org/10.1042/BCJ20180347

Published: 10 December 2018

View articletitled, Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity

Includes: Supplementary data

Articles

GPCR structure and function relationship: identification of a biased apelin receptor mutant

Ting Ban, Xun Li, Xiaochuan Ma, Hui Yang, Yunpeng Song, Yaping Sun, Michelle Shen, Na Li, Mei-Yun Zhang, Yingli Ma, Wenge Zhong, Mingqiang Zhang, Liaoyuan A. Hu

Biochem J (2018) 475 (23): 3813–3826.

https://doi.org/10.1042/BCJ20180740

Published: 06 December 2018

View articletitled, GPCR structure and function relationship: identification of a biased apelin receptor mutant

Includes: Supplementary data

Articles

Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant

Jo Ann Janovick, Timothy P. Spicer, Thomas D. Bannister, Emery Smith, Vadivel Ganapathy, Louis Scampavia

Biochem J (2018) 475 (18): 2941–2953.

https://doi.org/10.1042/BCJ20180065

Published: 25 September 2018

View articletitled, Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant

Update search

Email alerts

CONNECT

EXPLORE

This Feature Is Available To Subscribers Only