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Keywords: 3T3-L1 cell
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Articles
Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus
Available to PurchaseWulin Yang, Shermaine Thein, Xiangxiang Guo, Feng Xu, Byrappa Venkatesh, Shigeki Sugii, George K. Radda, Weiping Han
Journal:
Biochemical Journal
Biochem J (2013) 452 (1): 37–44.
Published: 25 April 2013
... in nonadipocytes, which was mediated by the core sequence. In contrast, seipin overexpression did not inhibit LD accumulation during adipocyte differentiation or the adipogenic process in 3T3-L1 cells. However, adipogenesis and LD accumulation were impaired in 3T3-L1 cells expressing a seipin mutant lacking the C...
Includes: Supplementary data
Articles
Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process
Available to PurchaseLise MADSEN, Rasmus K. PETERSEN, Morten B. SØRENSEN, Claus JØRGENSEN, Philip HALLENBORG, Lone PRIDAL, Jan FLECKNER, Ez-Zoubir AMRI, Peter KRIEG, Gerhard FURSTENBERGER, Rolf K. BERGE, Karsten KRISTIANSEN
Journal:
Biochemical Journal
Biochem J (2003) 375 (3): 539–549.
Published: 01 November 2003
... of LOXs (lipoxygenases) during adipocyte differentiation of 3T3-L1 cells. We show that adipocyte differentiation of 3T3-L1 preadipocytes is inhibited by the general LOX inhibitor NDGA (nordihydroguaiaretic acid) and the 12/15-LOX selective inhibitor baicalein. Baicalein-mediated inhibition of adipocyte...
Articles
Only the large soluble form of preadipocyte factor-1 (Pref-1), but not the small soluble and membrane forms, inhibits adipocyte differentiation: role of alternative splicing
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2002) 364 (1): 137–144.
Published: 08 May 2002
...Baisong MEI; Ling ZHAO; Li CHEN; Hei Sook SUL We originally identified preadipocyte factor-1 (Pref-1) as an inhibitor of adipogenesis by the fact that constitutive expression of full-length Pref-1A inhibits differentiation of 3T3-L1 cells into adipocytes. Subsequently, we found that the membrane...
