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Keywords: ADP-ribosylation
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Biochem J (2022) 479 (4): 463–477.
Published: 17 February 2022
...Marion Schuller; Ivan Ahel ADP-ribosylation has primarily been known as post-translational modification of proteins. As signalling strategy conserved in all domains of life, it modulates substrate activity, localisation, stability or interactions, thereby regulating a variety of cellular processes...
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Biochem J (2007) 402 (2): 205–218.
Published: 12 February 2007
... forms, NAD + and NADP + , have been identified as important elements of regulatory pathways. In particular, NAD + serves as a substrate for ADP-ribosylation reactions and for the Sir2 family of NAD + -dependent protein deacetylases as well as a precursor of the calcium mobilizing molecule cADPr (cyclic...
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Biochem J (2002) 362 (3): 717–723.
Published: 08 March 2002
... , characteristic of a cysteine-linked ADP-ribosylation. 1 To whom correspondence should be addressed (e-mail [email protected] ) 13 6 2001 26 11 2001 17 1 2002 The Biochemical Society, London ©2002 2002 ADP-ribosylation cell activation target amino acid...
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Biochem J (2000) 349 (3): 697–701.
Published: 25 July 2000
...). In the present study we identify the interaction site on ExoS for 14-3-3, and show that ExoS and 14-3-3 do indeed interact in vivo . In addition, we show that this interaction is critical for the ADP-ribosylation of Ras by ExoS, both in vitro and in vivo . Loss of the 14-3-3 binding site on ExoS results...