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Keywords: Acrodermatitis Enteropathica
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Biochem J (2019) 476 (12): 1791–1803.
Published: 28 June 2019
... is exclusively responsible for zinc uptake from dietary food and dysfunctional mutations of ZIP4 cause a life-threatening genetic disorder, Acrodermatitis Enteropathica (AE). About half of the missense AE-causing mutations occur within the large N-terminal extracellular domain (ECD), and our previous study has...
Includes: Supplementary data