... <0.05. Akt substrate of 160 kDa (AS160) glucose transport insulin resistance liver muscle Insulin-regulated disposal of glucose from the bloodstream into skeletal muscle and fat tissues is mediated by the glucose transporter GLUT4, which undergoes translocation from intracellular...

... muscle. 1 To whom correspondence should be addressed (email [email protected] ). 8 5 2012 3 7 2012 13 7 2012 13 7 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 Akti Akt substrate of 160 kDa (AS160) glucose uptake glycogen...

... together, our data suggest that TBC1D1 may be involved in controlling GLUT1 glucose transporter expression through the mTOR-p70 S6 kinase pathway. Akt substrate of 160 kDa (AS160) GLUT1 GTPase-activating protein (GAP) insulin signalling mammalian target of rapamycin (mTOR) protein kinase B (PKB...

... substrate of 160 kDa (AS160) AMP-activated protein kinase (AMPK) metformin obesity protein kinase B (PKB) TBC1D1 Rabs are GTP-activated proteins that regulate the flow of vesicle traffic between organelles by interacting with effectors of vesicle formation, motility, docking and fusion [ 1...

... propionate)] was from Perbio. Protein G–Sepharose and other chromatographic matrices were from GE Healthcare. All other chemicals were from BDH Chemicals or Sigma–Aldrich. 14-3-3 Akt/protein kinase B (PKB) Akt substrate of 160 kDa (AS160) GTPase-activating protein (GAP) p90 ribosomal S6 kinase (RSK...

... 23 6 2005 23 6 2005 The Biochemical Society, London 2005 Akt Akt substrate of 160 kDa (AS160) GTPase-activating protein (GAP) GLUT4 Rab Insulin treatment of fat and muscle cells causes a rapid increase in glucose transport. This increase is due to a rise in glucose...