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Keywords: Alix
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Biochem J (2015) 466 (3): 475–487.
Published: 06 March 2015
... for degradation of these receptors in lysosomes. The adaptor protein Alix is critically involved in multiple ESCRT-III-mediated, membrane-remodelling processes in mammalian cells. However, Alix knockdown does not inhibit degradation of the activated epidermal growth factor receptor (EGFR) in mammalian cell lines...
Includes: Supplementary data