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Keywords: Arp2/3 complex
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Articles
Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization
Available to PurchaseJean Paul ten Klooster, Eva E. Evers, Lennert Janssen, Laura M. Machesky, Frits Michiels, Peter Hordijk, John G. Collard
Journal:
Biochemical Journal
Biochem J (2006) 397 (1): 39–45.
Published: 14 June 2006
... the actin cytoskeleton through the GTPase, Rac1. Using yeast two-hybrid screening and biochemical assays, we found that Tiam1 interacts with the p21-Arc [Arp (actin-related protein) complex] subunit of the Arp2/3 complex. Association occurred through the N-terminal pleckstrin homology domain...
Articles
Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2004) 380 (1): 1–17.
Published: 15 May 2004
...Thomas H. MILLARD; Stewart J. SHARP; Laura M. MACHESKY The assembly of a branched network of actin filaments provides the mechanical propulsion that drives a range of dynamic cellular processes, including cell motility. The Arp2/3 complex is a crucial component of such filament networks. Arp2/3...
Articles
Actions by actin: reciprocal regulation of cortactin activity by tyrosine kinases and F-actin
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2004) 380 (1): e7–e8.
Published: 15 May 2004
...Susan J. GUNST The polymerization of actin is catalysed by the Arp (actin-related protein) 2/3 complex, which acts downstream of a variety of receptors and signalling cascades. Intermediary molecules such as cortactin bind to the Arp2/3 complex and stimulate its activity, thus promoting actin...
